Results 121 to 130 of about 81,851 (305)

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

The influence of rare KLF1 gene mutations on fetal hemoglobin levels and their association with thalassemia

Guangxi Yike Daxue xuebao
Objective To study the influence of KLF1 gene mutations on fetal hemoglobin (Hb F) levels and their effects on thalassemia. Methods Cases undergoing thalassemia screening at the First Affiliated Hospital of Guangxi Medical University from March 2023 to ...
Zixuan CHAI, Hengying ZHU, Xuan XIAO, Ping CHEN   +3 more
doaj   +1 more source

Genomic architecture and breeding trade‐offs of coconut drought tolerance

PLANTS, PEOPLE, PLANET, EarlyView.
The coconut palm is an extremely popular and economically important crop, with around 65 million tonnes produced in 2023. Although Africa's coconut sector is growing rapidly, it—and the livelihoods that depend on it—is threatened by climate change, particularly increased drought.
Theodore S. Brook, Tom Versluys, Bi Tra Serges Doubi, Sam Acors, Jahcub Trew, Kyle Macleod, Louis Bell‐Roberts, Katarina Piponi, Jean Louis Konan, Konan Engueran Djaha, Hala N'klo, Benjamin J. Roberts, Catherine M. Collins, Matteo Fumagalli, Julien Godwin, Vincent Savolainen   +15 more
wiley   +1 more source

Heterozygote deficits in cyst plant-parasitic nematodes: possible causes and consequences

, 2015
International audienceDeviations of genotypic frequencies from Hardy-Weinberg equilibrium (HWE) expectations could reveal important aspects of the biology of populations. Deviations from HWE due to heterozygote deficits have been recorded for three plant-
Pierre-Loup, Jan, Jan, Pierre-Loup, Fournet, Sylvain, Overall, Andrew, Overall, Andrew D. J., Gracianne, Cécile, Montarry, Josselin, Overall, Andrew D.J., Olivier, Eric, Petit, Eric J., Bardou-Valette, Sylvie, Grenier, Eric, Petit, Eric   +12 more
core   +1 more source

The first report of M918L (super‐kdr) and L932F voltage‐gated sodium channel mutations in the English grain aphid (Sitobion avenae)

Pest Management Science, EarlyView.
The study has identified mutations in the voltage gated sodium channel of the English grain aphid (Sitobion avenae) at M918 and L932, which have not been previously reported in this species. Abstract BACKGROUND The grain aphid, Sitobion avenae Fabricius (Hemiptera: Aphididae), is a vector of yellow dwarf viruses and an important pest of cereals.
Virgile Ballandras, Louise McNamara, James C Carolan, Tom Ruttink, Stephen Byrne   +4 more
wiley   +1 more source

Comparison of homozygote (gt/gt) testes with heterozygote (+/gt) testes.

, 2016
A) Heterozygote (+/gt) and homozygote (gt/gt) testes removed from 4-month-old littermate mice were compared. B) Histological sections of +/gt (Jmjd1C +/gt) heterozygote (a, b) and gt/gt (Jmjd1C gt/gt) homozygote (d, e) testes from 4-month-old littermate ...
Ryusuke Nakajima (3129279), Toshiaki Noce (242615), Hideyuki Okano (47690)   +2 more
core   +1 more source

Congenital polycythemia with homozygous and heterozygous mutations of von Hippel-Lindau gene: five new Caucasian patients

Haematologica, 2005
We report on five Caucasian patients with congenital polycythemia and mutations of the von Hipple-Lindau (VHL) gene: a compound heterozygote for the novel exon 1 (VHL 235C->T) and previously reported VHL 562C->G mutations; three homozygotes for Chuvash ...
MC Bento, KT Chang, Y Guan, E Liu, G Caldas, RA Gatti, JT Prchal   +6 more
doaj  

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source

Reduced fitness cost accounts for the stability of a malathion‐resistant heterogeneous duplication haplotype in Ceratitis capitata field populations

Pest Management Science, EarlyView.
Malathion resistance in Spanish field populations of Ceratitis capitata is associated with a point mutation (R allele) and a heterogeneous duplication (RS haplotype) of the Ccace2 gene. The R allele imposes a higher fitness cost than the RS haplotype under laboratory and field conditions. An evolutionary model supports the stability of the RS haplotype
Rabeh Arouri, Francisco Couso‐Ferrer, Elena López‐Errasquín, Beatriz Beroiz, Lucas Sánchez, Pedro Hernández‐Crespo, Félix Ortego   +6 more
wiley   +1 more source

Conflict between heterozygote advantage and hybrid incompatibility in haplodiploids (and sex chromosomes)

, 2017
In many diploid species the sex chromosomes play a special role in mediating reproductive isolation. In haplodiploids, where females are diploid and males haploid, the whole genome behaves similarly to the X/Z chromosomes of diploids.
Alexandre Blanckaert, Roger K. Butlin, Ana-Hermina Ghenu, Jonna Kulmuni, Claudia Bank   +4 more
core   +1 more source