Results 161 to 170 of about 78,400 (304)

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Rhesus macaques with an <i>OPA1</i> mutation demonstrate features of autosomal dominant optic atrophy. [PDF]

Proc Natl Acad Sci U S A
Jaggers TN, Ripolles-Garcia A, Moshiri A, Story BD, Wang J, Chen R, Moore LG, Teixeira LBC, Shim J, Raposo AC, Casanova MI, Le SM, Park S, Young LJ, Kim S, Roszak KP, Ureno V, Karpinen PM, Echeverria N, Ardon M, Leonard BC, Knipe M, Bliss-Moreau E, Fortune B, Stout JT, Rogers J, Marsh-Armstrong N, Thomasy SM.   +27 more
europepmc   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

LRRK2 and GBA1 in Lewy body diseases: neuropathological subtypes at opposite ends of a spectrum? [PDF]

Mol Neurodegener
Jha V, Kalia LV.
europepmc   +1 more source

heterozygote advantage

Citation: 'heterozygote advantage' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14743 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

The rs10781468 Genetic Polymorphism of the Gαq (GNAQ) Gene Is Associated With Responsiveness to Opioid Analgesics in Patients With Postoperative and Cancer Pain: An Exploratory Study

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
In our exploratory hypothesis‐generating study using patients with postoperative pain and cancer pain, for rs10781468 in the GNAQ gene, the minor allele was associated with reduced opioid consumption and an increased pain threshold. ABSTRACT Background G protein–coupled receptors, the largest class of cell surface receptors, are ubiquitously expressed ...
Hiroaki Owada, Daisuke Nishizawa, Tsutomu Mieda, Miki Tsujita, Hideyuki Nakagawa, Shigeki Yamaguchi, Rikuhei Tsuchida, Yaeko Yokoshima, Akira Kitamura, Masakazu Hayashida, Ken‐ichi Fukuda, Tatsuya Ichinohe, Kazutaka Ikeda, Makoto Kurano, Masahiko Sumitani, Kanji Uchida   +15 more
wiley   +1 more source

Genetic Insights on Hypertriglyceridaemia-Induced Acute Pancreatitis in Pregnancy: A Case Series and Literature Review. [PDF]

Case Rep Endocrinol
Nguyen CS, Adams N, Gianatti E, Lee IL, Kevat D.   +4 more
europepmc   +1 more source

Resolving Taxonomic Boundaries in the New Zealand Senecio matatini Complex (Senecioneae, Asteraceae): Evidence from Genotyping by Sequencing of Limestone‐Associated Forms

New Zealand Journal of Botany, Volume 64, Issue 3, September 2026.
The Senecio matatini complex in New Zealand has a convoluted taxonomic and nomenclatural history that has not been fully resolved. This is largely due to the incomplete sampling of morphologically diverse but highly threatened limestone populations in the eastern South Island in previous genetic studies.
Samiksha Patel, Robb W. Eastman‐Densem, Peter B. Heenan, Pieter B. Pelser   +3 more
wiley   +1 more source

Sex‐Linked Dilution Colour in the European Domestic Goose Indicated To Be a 1‐Bp Deletion in the Melan‐A Gene

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Plumage colour in domestic geese is an important economic trait and a selection target since the early days of domestication. In European domestic geese of greylag goose (Anser anser) origin, white plumage is known to be determined by two independent loci, one causing white spotting and another sex‐linked dilution, together producing white ...
Suvi Olli, Vikke Ahola, Marja E. Heikkinen, Johanna Honka   +3 more
wiley   +1 more source

Lecanemab and amyloid-related imaging abnormalities: Real-world data from a single center experience. [PDF]

Alzheimers Dement (Amst)
Wallace A, Zhou O, Hoang MN, Porter G, Padilla C, Marshall C.   +5 more
europepmc   +1 more source