Results 181 to 190 of about 114,605 (302)

Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol‐related behaviour and affective state in mice

British Journal of Pharmacology, Volume 183, Issue 11, Page 3111-3128, June 2026.
Abstract Background and Purpose Alcohol abuse and affective disorders are severe comorbid psychiatric diseases characterized by impaired brain synaptic transmission. The role of presynaptic scaffolding proteins coordinating presynaptic plasticity and neurotransmitter release, such as Bassoon (Bsn), in the pathogenesis of these disorders remains elusive.
Liubov S. Kalinichenko, Mona Krenbauer, Janosh Isert, Marlon Kamlah, Thorben Tanzer, Hannes Rödel, Tobias Müller, Anil Annamneedi, Enes Yağız Akdaş, Volker Eulenburg, Bernd Lenz, Eckart D. Gundelfinger, Johannes Kornhuber, Anna Fejtova, Christian P. Müller   +14 more
wiley   +1 more source

Different larval habitats and insecticide resistance frequency of Anopheles sinensis in Ganghwagun, Incheon, South Korea. [PDF]

Sci Rep
Eom TH, Lee HY, Hong H, Lee E, Lee J, Eun JH, Seo S, Goh Y, Lee E, Yeo SJ.   +9 more
europepmc   +1 more source

Biallelic MYH3 Variants Cause Distal Arthrogryposis in Compound Heterozygosity and a Subclinical Phenotype in Simple Heterozygosity. Codominance or Recessive Inheritance?

Clinical Genetics, Volume 109, Issue 6, Page 1059-1063, June 2026.
A nuclear family affected by distal arthrogryposis with novel biallelic MYH3 variants, which at the heterozygous state yield a subclinical phenotype, highlighting the complexity of MYH3‐related disorders and their inheritance modes. ABSTRACT Distal arthrogryposis constitutes a highly heterogeneous group of disorders with a critical need for clear ...
Omar Zgheib, Thomas Rio‐Frio, Michel Guipponi, Thierry Nouspikel, Siv Fokstuen, Marc Abramowicz, Philippe Khau Van Kien   +6 more
wiley   +1 more source

A feasibility study of whole genome germline testing as an adjunct screening tool in a UK general private practice. [PDF]

Sci Rep
Jones AB, Pichert G, Side L, Homfray T, McVeigh T, Hicks S, Williams C, Pellerin D, Cirigliano V, Leon M, Palao B, Izquierdo L, Ordonez E, Gongora E, Davies C, Healy J, Thomas R, Narayanan P, Al Shakarchi G, Amin Z, Dadaev T, Bancroft E, Kote-Jarai Z, Eeles R, Sandberg M.   +24 more
europepmc   +1 more source

Silene, a versatile model system: from sex and genome evolution to ecology and speciation

New Phytologist, Volume 250, Issue 6, Page 3613-3630, June 2026.
Summary Fundamental and applied research in evolutionary biology benefits from the use of model systems in which approaches from disparate disciplines can be integrated. Here, we review recent progress in evolutionary research on the long‐standing model system Silene, a large genus with a well‐resolved phylogeny and newly available, expanded genomic ...
Sophie Karrenberg, Václav Bačovský, Andrea E. Berardi, Isabelle De Cauwer, Tatiana Giraud, Fanny E. Hartmann, Roman Hobza, Vojtěch Hudzieczek, Gabriel A.B. Marais, Jenna R. Miladin, Bengt Oxelman, Alexander S.T. Papadopulos, Daniel B. Sloan, Janet C. Steven, Helena Štorchová, Pascal Touzet, Fabienne Van Rossum   +16 more
wiley   +1 more source

Emerging from the shadows of congenital TTP. [PDF]

Blood Adv
Scully M, Cox C.
europepmc   +1 more source

OPA1 in MC4R Neurons Regulates Dietary Fat Intake and Body Weight in Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Soybean oil intake induces OPA1 expression in hypothalamic MC4R neurons, contributing to adaptive regulation of appetite. MC4R neuron‐specific OPA1 deficiency increases soybean oil consumption and leads to obesity, with a more pronounced effect in females.
Shigenobu Matsumura, Mizuki Fujiwara, Soyoka Horie, Miona Marutani, Eri Nousou, Nanase Iki, Yuka Yamato, Yui Otonashi, Tsutomu Sasaki, Mina Fujitani, Teppei Fujikawa   +10 more
wiley   +1 more source

Prevalence of double heterozygotes of HbE and α-thal 1 (SEA) type in pregnancies and their partners that received antenatal care at Chiangrai Prachanukroh Hospital and reevaluated the cut-offs for differentiation. [PDF]

PLoS One
Leckngam P, Wamontree P, Chuaykarn T.
europepmc   +1 more source

Macrophage‐Fibroblast Crosstalk Shapes Wound Repair Signaling In Vitro

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Intercellular communication between macrophages and fibroblasts is critical for wound healing. Macrophages promoted fibroblast scratch closure through contact‐dependent mechanisms independent of connexins. In contrast, fibroblasts regulated macrophage cytokine secretion via connexin‐43–mediated contact signaling that increased IL10 and paracrine ...
Daniela Enriquez‐Ochoa, Raji R. Nagalla, Yingzi Liu, Christian F. Guerrero‐Juarez, Hamza Atcha, Gordon Chang, Nancy A. Morales, Hannah J. Hooper, Arian D. Cano, Huy Eng Lim, Michael D. Cahalan, Maksim V. Plikus, Wendy F. Liu   +12 more
wiley   +1 more source

Phenotypic dominance emerges from activity fitness functions and molecular interactions. [PDF]

Genetics
Pal T, Dibyachintan S, Cisneros AF, Landry CR.   +3 more
europepmc   +1 more source