Results 181 to 190 of about 78,400 (304)

Relative Exchangeable Copper Confirms Wilson Disease and Supports Reclassification of the ATP7B p.Met665Ile Variant With Conflicting Pathogenicity Evidence

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1691-1695, July 2026.
ABSTRACT Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by ATP7B mutations. Diagnosis is usually straightforward in symptomatic patients, but can be challenging in children and adolescents with mild liver disease, borderline urinary copper excretion, or inconclusive genetic findings.
Emanuele Nicastro, Caterina Zuccoli, Roberto Marozzi, Antonino Barletta, Lisa Licini, Paola Tebaldi, Valeria Casotti, Mariangela Stinco, Lidia Pezzani, Maria Iascone, Lorenzo D'Antiga   +10 more
wiley   +1 more source

Microsatellite-based assessment of genetic diversity and inbreeding in the Ukrainian water buffalo (<i>Bubalus bubalis</i>) population. [PDF]

Vet World
Mokhnachova N, Skrepets K, Zhukorskyi O, Starodub L, Ladyka V, Tymchenko O.   +5 more
europepmc   +1 more source

Genetic Polymorphism – A Result of LocalAdaptation or Heterozygote Advantage?

Stable coexistence of different self-reproducing entities requires negative frequency dependence, such that each type has an advantage when rare. In community ecology, the entities of interest are species or morphs, and negative frequency dependence ...
Siljestam, Mattias,, Rüffler, Claus,
core  

Associations of self‐reported obstructive sleep apnea with cognition and dementia risk in cognitively unimpaired middle‐aged adults

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Obstructive sleep apnea (OSA) is a potential risk factor for cognitive impairment and dementia; however, its contribution in midlife and interactions with APOE ε4 remain unclear. METHODS Participants were 2795 cognitively unimpaired, middle‐aged adults enrolled in the Healthy Brain Project. OSA status was determined by self‐report.
Gabriel T. Abdelmessih, Lisa Bransby, Hannah Cummins, Melinda L. Jackson, Yen Ying Lim   +4 more
wiley   +1 more source

A New Method for Screening Thalassemia Patients Using Mid-Infrared Spectroscopy. [PDF]

Diagnostics (Basel)
Thumanu K, Khamgasem T, Sukpong S, Phatthanakun R, Puangplruk R, Tanthanuch W, Kuaprasert B, Tastub S, Rujanakraikarn R, Tun S, Saovana T, Munkongdee T, Wongthong S.   +12 more
europepmc   +1 more source

Evidence of APOE4‐related brain vulnerabilities in verbal memory systems in midlife women

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Women carrying the apolipoprotein E4 (APOE4) allele have a greater risk of Alzheimer's disease (AD) from ages 65‐75 years compared to men, yet the effects of APOE4 on cognitive and neuroimaging outcomes among midlife women remain poorly understood.
Katrina A. Wugalter, Rebecca C. Thurston, Minjie Wu, Howard J. Aizenstein, M. Ilyas Kamboh, Thomas K. Karikari, Pauline M. Maki   +6 more
wiley   +1 more source

Impact of genetic profiles on periventricular anastomosis following bypass surgery in moyamoya disease. [PDF]

Neurosurg Rev
Torazawa S, Miyawaki S, Imai H, Hongo H, Shimizu M, Ono H, Ogawa S, Sakai Y, Kiyofuji S, Koizumi S, Komura D, Katoh H, Ishikawa S, Saito N.   +13 more
europepmc   +1 more source

Lecanemab treatment improves B cell subpopulation immune homeostasis in patients with Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Lecanemab, the first disease‐modifying therapy for Alzheimer's disease (AD), mitigates pathology primarily by clearing amyloid plaques, but its impact on peripheral immunity remains unclear. METHODS To assess Lecanemab's immunological effects, we performed antibody array analysis of serum and single‐cell RNA sequencing of ...
Yutong Cai, Yuxuan Wang, Wenjing Huang, Ying Su, Ming Lei, Ruonan Jia, Chenyue Wu, Tianming Zhang, Lanlan Sun, Bihao Peng, Jun Cheng, Jintai Yu, Xiaochun Chen, Qinyong Ye, Jian Yu, Jiawei Xin   +15 more
wiley   +1 more source

Population Structure and Genetic Diversity Among Lipizzan Mare Families in Hungary Based on Microsatellite Genotyping. [PDF]

Animals (Basel)
Kovács M, Hegedűs B, Mihók S, Knop R, Szabó C, Posta J.   +5 more
europepmc   +1 more source

First Insight Into Multiple Paternity in the Potato Cyst Nematode Globodera pallida Facing Masculinizing Plant Resistance

Ecology and Evolution, Volume 16, Issue 7, July 2026.
This study demonstrated multiple paternity in the potato cyst nematode Globodera pallida: all females were polyandrous. Moreover, the female mating rate with different males appeared to remain stable, i.e., an average of seven fathering males, throughout the adaptation process to a masculinizing potato resistance.
Magali Esquibet, Océane Lechevalier, Nathan Garcia, Sylvain Fournet, Eric Grenier, Josselin Montarry   +5 more
wiley   +1 more source