Results 31 to 40 of about 299,280 (207)

The panorama of familial hypercholesterolemia in Latin America: a systematic review[S]

Journal of Lipid Research, 2016
The burden caused by familial hypercholesterolemia (FH) varies among countries and ethnic groups. The prevalence and characteristics of FH in Latin American (LA) countries is largely unknown. We present a systematic review (following the PRISMA statement)
Roopa Mehta, Rafael Zubirán, Alexandro J. Martagón, Alejandra Vazquez-Cárdenas, Yayoi Segura-Kato, María Teresa Tusié-Luna, Carlos A. Aguilar-Salinas   +6 more
doaj   +1 more source

Burden of cardiovascular disease in a large contemporary cohort of patients with heterozygous familial hypercholesterolemia. [PDF]

Atheroscler Plus, 2022
BACKGROUND AND AIMS: Heterozygous familial hypercholesterolemia (HeFH) is increasingly better diagnosed and treatments can improve the cardiovascular prognosis.
Ferrières J, Farnier M, Bruckert E, Vimont A, Durlach V, Ferrari E, Gallo A, Boccara F, Ferrières D, Béliard S, French FH Registry group: French REgistry of Familial hypERCHOLesterolemia (REFERCHOL).   +10 more
europepmc   +2 more sources

Anti-PCSK9 antibodies for the treatment of heterozygous familial hypercholesterolemia: patient selection and perspectives [PDF]

, 2017
Alberico Luigi Catapano,1,2 Angela Pirillo,1,2 Giuseppe Danilo Norata1,3,4 1Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 2IRCCS Multimedica Hospital, Sesto San Giovanni, 3Center for the Study of ...
Pirillo A, Norata GD, Catapano AL
core   +3 more sources

Clinical case of myocardial infarction with unspecified familial hypercholesterolemia

Атеросклероз, 2022
Familial hypercholesterolemia is a hereditary autosomal dominant disease characterized by a violation of cholesterol metabolism. This nosology was first described in the late 1930s by the Norwegian clinician Karl Moeller, he proposed the idea that ...
Natalya G. Lozhkina, Aleksandr N. Spiridonov   +1 more
doaj   +1 more source

Triple Assessments of Atherosclerosis in Patients With Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Asia
Data on the appropriate timing and impact of atherosclerosis assessment in patients with heterozygous familial hypercholesterolemia (HeFH) are limited.The authors aimed to determine when atherosclerotic changes occur and the utility of triple assessments of carotid plaque, coronary plaque, and coronary artery calcium (CAC) in patients with HeFH.Data ...
Tada H, Kojima N, Yamagami K, Nomura A, Nohara A, Usui S, Sakata K, Kawashiri MA, Takamura M.   +8 more
europepmc   +4 more sources

Familial hypercholesterolemia: A review

Annals of Pediatric Cardiology, 2014
Familial hypercholesterolemia (FH) is a genetic disorder of lipoprotein metabolism resulting in elevated serum low-density lipoprotein (LDL) cholesterol levels leading to increased risk for premature cardiovascular diseases (CVDs).
Mithun J Varghese
doaj   +1 more source

Distinguishing Lysosomal Acid Lipase Deficiency From Familial Hypercholesterolemia

JACC: Case Reports, 2023
Lysosomal acid lipase deficiency (LAL-D) is underrecognized because it manifests clinically with lipid and lipoprotein values similar to those observed in heterozygous familial hypercholesterolemia (FH).
Sohum Sheth, BS, Peter P. Toth, MD, PhD, Seth J. Baum, MD, Monica Aggarwal, MD   +3 more
doaj   +1 more source

Use of targeted exome sequencing in genetic diagnosis of Chinese familial hypercholesterolemia. [PDF]

PLoS ONE, 2014
Familial hypercholesterolemia is an autosomal dominant inherited disease characterized by elevated plasma low-density lipoprotein cholesterol (LDL-C). It is mainly caused by mutations of the low-density lipoprotein receptor (LDLR) gene.
Wen-Feng Wu, Li-Yuan Sun, Xiao-Dong Pan, Shi-Wei Yang, Lv-Ya Wang   +4 more
doaj   +1 more source

Genetic and Clinical Characteristics of Patients With Homozygous and Compound Heterozygous Familial Hypercholesterolemia From Three Different Populations: Case Series

Frontiers in Genetics, 2020
Homozygous familial hypercholesterolemia (HoFH) and compound heterozygous familial hypercholesterolemia (cHeFH) are rare disorders generated by disease-causing variants in both alleles of the LDLR or other familial hypercholesterolemia (FH)-related genes.
Tatiana Marusic, Ursa Sustar, Fouzia Sadiq, Vjosa Kotori, Matej Mlinaric, Jernej Kovac, Saeed Shafi, Iqbal Khan, Iqbal Khan, Matija Cevc, Katarina Trebusak Podkrajsek, Katarina Trebusak Podkrajsek, Tadej Battelino, Tadej Battelino, Urh Groselj, Urh Groselj   +15 more
doaj   +1 more source

Assessments of Atherosclerosis and Treatment Strategies for Heterozygous Familial Hypercholesterolemia. [PDF]

J Atheroscler Thromb
Patients with familial hypercholesterolemia (FH) carry an extremely elevated cardiovascular risk because of lifelong exposure to elevated low-density lipoprotein cholesterol (LDL-C). The Japan Atherosclerosis Society (JAS) complies with the clinical guidelines of FH stipulating diagnostic criteria as well as the treatment targets based on their ...
Tada H, Harada-Shiba M.
europepmc   +4 more sources