Results 271 to 280 of about 344,625 (347)

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

open access: yesBMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu   +12 more
wiley   +1 more source

<i>Equisetum hyemale</i> L. Extracts: Phytochemistry, Biological Performance, ADMET Profiling, and Toxicity Predictions. [PDF]

open access: yesPharmaceuticals (Basel)
Minutti-Calva Y   +12 more
europepmc   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

open access: yesBMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng   +5 more
wiley   +1 more source

Improving Antioxidants and Physicochemical Properties of Wild Rice Noodles by Fortification With Carrot Powder

open access: yesCereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Wild rice (WR), a nutritious cereal rich in phytochemicals, remains underutilized despite its health benefits. This study explored deep purple (DP), purple sun hybrid (PSH), purple haze (PH), cosmic purple (CP), and vistaric sky blue (VSB) carrot powders as fortificants in WR noodles at 10%, 20%, and 30% levels in ...
Beverly Cheruto Too   +3 more
wiley   +1 more source

Establishing Indium in Frustrated Lewis Pair Chemistry: From Synthesis to Catalytic Applications

open access: yesChemistryEurope, EarlyView.
Not that hard: The effects of chemical hardness of the soft FLP tBu2InCH2PtBu2 and its pyridine‐adduct tBu2In(py)CH2PtBu2 were examined in adduct formation reactions toward H2, CO2, and CS2. The frustrated Lewis pair shows catalytic activity in the reduction of CO2 with pinacolborane.
Daniel N. Heuer   +6 more
wiley   +1 more source

Electrophilic Functionalization of Donor‐Stabilized Phosphanylboranes: A New Pathway toward Heavy 13/14/15 Parent Hydride‐Containing Compounds

open access: yesChemistryEurope, EarlyView.
A new way of obtaining mixed 13/14/15 hydride containing compounds stabilized only by a Lewis base is presented. The functionalization of IDipp·BH2PH2 (IDipp = 1,3‐Bis‐(2,6‐diisopropylphenyl)‐imidazolin‐2‐ylidene) by main group electrophiles leads to the formation of the compounds [IDipp·BH2PH2E]+ [E = H, CH3 SiEt3, Ge(SiMe3)3, SnMe3) which represent a
Robert Szlosek   +7 more
wiley   +1 more source

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