Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source
<i>Equisetum hyemale</i> L. Extracts: Phytochemistry, Biological Performance, ADMET Profiling, and Toxicity Predictions. [PDF]
Minutti-Calva Y +12 more
europepmc +1 more source
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng +5 more
wiley +1 more source
Neuroprotective Effect of Fresh Gac Fruit Parts Against β-Amyloid-Induced Toxicity and Its Influence on Synaptic Gene Expression in HT-22 Cell Model. [PDF]
Ali A, Lin CL, Wang CK.
europepmc +1 more source
ABSTRACT Background and Objectives Wild rice (WR), a nutritious cereal rich in phytochemicals, remains underutilized despite its health benefits. This study explored deep purple (DP), purple sun hybrid (PSH), purple haze (PH), cosmic purple (CP), and vistaric sky blue (VSB) carrot powders as fortificants in WR noodles at 10%, 20%, and 30% levels in ...
Beverly Cheruto Too +3 more
wiley +1 more source
Mechanisms of Antiproliferative Effects of Nobiletin, Scoparone, and Tangeretin Isolated from <i>Citrus reticulata</i> Peel Dichloromethane Extract in Acute Myeloid Leukemia Cells. [PDF]
Russo C +4 more
europepmc +1 more source
Establishing Indium in Frustrated Lewis Pair Chemistry: From Synthesis to Catalytic Applications
Not that hard: The effects of chemical hardness of the soft FLP tBu2InCH2PtBu2 and its pyridine‐adduct tBu2In(py)CH2PtBu2 were examined in adduct formation reactions toward H2, CO2, and CS2. The frustrated Lewis pair shows catalytic activity in the reduction of CO2 with pinacolborane.
Daniel N. Heuer +6 more
wiley +1 more source
Effect of Organic Compounds and Alkalinity on the Stability of Bulk Nanobubbles: A Molecular Dynamics Study. [PDF]
Kaumbekova S +5 more
europepmc +1 more source
A new way of obtaining mixed 13/14/15 hydride containing compounds stabilized only by a Lewis base is presented. The functionalization of IDipp·BH2PH2 (IDipp = 1,3‐Bis‐(2,6‐diisopropylphenyl)‐imidazolin‐2‐ylidene) by main group electrophiles leads to the formation of the compounds [IDipp·BH2PH2E]+ [E = H, CH3 SiEt3, Ge(SiMe3)3, SnMe3) which represent a
Robert Szlosek +7 more
wiley +1 more source

