Results 91 to 100 of about 7,764 (216)

Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors

open access: yes
2-Acetamido-1,2-dideoxyiminosugars are selective and potent inhibitors of hexosaminidases and therefore show high therapeutic potential for the treatment of various diseases, including several lysosomal storage disorders. A stereoselective synthesis of 2-
Fuente Cebrián, Àlex de la   +6 more
core  

SEPARATION DES ISOENZYMES DE L'HEXOSAMINIDASE DANS LES LEUCOCYTES ET LES CULTURES DE FIBROBLASTES ET CELLULES AMNIOTIQUES NORMALES :MISE EN EVIDENCE DE TROIS FRACTIONS

open access: yes, 1973
By using the electrophoresis of hexosaminidases in very concentrated extracts containing leucocytes, fibroblastic cultures and normal amniotic cells, the 3 fractions are constantly separated.
Mandelbaum, Israel   +2 more
core  

Mucin-driven ecological interactions in an in vitro synthetic community of human gut microbes. [PDF]

open access: yesGlycobiology
Berkhout MD   +5 more
europepmc   +1 more source

Human hexosaminidases : databases and modelling analysis

open access: yes, 2000
The GM2 gangliosidoses are a group of recessive disorders, which lead to the accumulation of GM2 ganglioside in neuronal cells. The genes responsible for these disorders are HEXA (Tay-Sachs disease and variants), HEXB (Sandhoff disease and variants) and ...
Cordeiro, Paulo.
core  

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