Isolation and Relationship of Human Hexosaminidases
Journal of Biological Chemistry, 1974 A method for the preparation of highly purified β-hexosaminidase isozymes A and B from human placenta is presented. The purified enzymes possess identical molecular weight and exhibit similar kinetic parameters with artificial fluorogenic substrates.
J F, Tallman +4 more
openaire +2 more sources
Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion [PDF]
, 2018 © 2018 Elsevier Ltd Small-molecule inhibitors of glycosylation can be applied in basic science studies, and clinical investigations as anti-inflammatory, anti-metastatic, and anti-viral therapies. This article demonstrates that thioglycosides represent a
Antonopoulos, Aristotelis +14 more
core +2 more sources
Legends of Allergy—Lawrence B. Schwartz
Allergy, Volume 81, Issue 4, Page 1315-1317, April 2026.
Gunnar P. Nilsson
wiley +1 more source
International Journal of Biological Sciences, 2012 Insect β-N-acetyl-D-hexosaminidases with broad substrate-spectrum (IBS-Hex) are the homologues of human β-N-acetyl-D-hexosaminidase A/B (HsHex A/ B). These enzymes are distributed in most insect species and vary in physiological roles.
Fengyi Liu, Tian Liu, Mingbo Qu, Qing Yang
doaj
Automated Assay of Hexosaminidases in Serum
Clinical Chemistry, 1973 Abstract In serum there are two classes of hexosaminidase. One of these is heat-labile and is inactive in children with Tay—Sachs disease. Serum from heterozygotes for Tay—Sachs disease has half the normal activity of the heat-labile enzyme.
J A, Lowden +3 more
openaire +2 more sources
GlcNAcstatin:a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels [PDF]
, 2006 Many phosphorylation signal transduction pathways in the eukaryotic cell are modulated by posttranslational modification of specific serines/threonines with N-acetylglucosamine (O-GlcNAc).
Borodkin, Vladimir S. +5 more
core +3 more sources
Enhancement of lysosomal glycohydrolase activity in human primary B lymphocytes during spontaneous apoptosis. [PDF]
, 2007 It has been shown that lysosomes are involved in B cell apoptosis but lysosomal glycohydrolases have never been investigated during this event. In this study we determined the enzymatic activities of some lysosomal glycohydrolases in human tonsil B ...
A. Frenguelli +9 more
core +2 more sources
A Study of Abscisic Acid Regulated Enzymes and Histone Binding Proteins in Plants [PDF]
, 2015 Plant hormone abscisic acid (ABA) plays a main role in coordinating various stress signals in plants. ABA regulates the expression of genes and activities of enzymes in response to various stress conditions. In the following studies we were able to study
Kolli, Udhghatri
core +1 more source
Increased trans-glycosylation activity of hexosaminidases for synthesis of human milk oligosaccharides [PDF]
, 2017 It is well known that the composition of human breast milk differs significantly from the one of ordinary bovine milk. Especially the presence of sialylated and fucosylated oligosaccharides contributes to its health and development promoting features for
Busk, Peter K. +6 more
core +1 more source
Enzymatic Hydrolysis of Human Milk Oligosaccharides. The Molecular Mechanism of Bifidobacterium Bifidum Lacto-N-biosidase [PDF]
Bifidobacterium bifidum lacto-N-biosidase (LnbB) is a critical enzyme for the degradation of human milk oligosaccharides in the gut microbiota of breast-fed infants.
Biarnés, Xevi +6 more
core +1 more source