Results 61 to 70 of about 7,764 (216)

N-acetyl-β-D-hexosaminidases mediate the generation of paucimannosidic proteins via a putative noncanonical truncation pathway in human neutrophils.

Glycobiology, 2021
Julian Ugonotti, Rebeca Kawahara, Ian Loke, Yuqi Zhu, S. Chatterjee, Harry C. Tjondro, Zeynep Sumer-Bayraktar, S. Neelamegham, M. Thaysen-Andersen   +8 more
semanticscholar   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Independent loss of human hexosaminidases A and B in man-Chinese hamster somatic cell hybrids

, 1973
The presence or absence of human hexosaminidases A and B was studied in 105 man-Chinese hamster hybrid cell clones. The results show that these two isoenzymes behave as independent markers.
Someren, H. van, Beijerbergen van Henegouwen, H.   +1 more
core  

Sequence analysis of OfHex3.

, 2013
(A) Phylogenetic relationships of OfHex3 with other insect β-N-acetyl-D-hexosaminidases. Phylogenetic tree was constructed with MEGA 5 using the neighbor-joining method with a bootstrap evaluation of 5,000 replications.
Mingbo Qu (444213), Tian Liu (78007), Peng Chen (6514), Qing Yang (67856)   +3 more
core   +1 more source

The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency

Clinical Genetics, Volume 110, Issue 1, Page 125-130, July 2026.
We identify a female patient with a homozygous nonsense variant (p.Gln38Ter) in the LYSET gene. This is the first western report of a challenging case of an extensive diagnostic odyssey and demonstrates that the LYSET gene must be considered in the differential diagnosis when M6P‐labeled lysosomal enzymes are altered.
Fernanda Sperb‐Ludwig, Taciane Alegra, Leonardo Martinello da Rosa, Nataniel Floriano Ludwig, Renata Voltolini Velho, Ida Vanessa Doederlein Schwartz   +5 more
wiley   +1 more source

O-GlcNAcase:promiscuous hexosaminidase or key regulator of O-GlcNAc signalling? [PDF]

, 2014
O-GlcNAc signalling is regulated by an opposing pair of enzymes: O-GlcNAc transferase (OGT) instals, and O-GlcNAcase (OGA) removes the modification from proteins.
van Aalten, Daan M. F., Alonso, Jana, Alonso , Jana, van Aalten, Daan M.F., Schimpl, Marianne   +4 more
core   +1 more source

Molecular and Biochemical Characterization of a Novel β-N-Acetyl-D-Hexosaminidase with Broad Substrate-Spectrum from the Aisan Corn Borer, Ostrinia Furnacalis

International Journal of Biological Sciences, 2012
Insect β-N-acetyl-D-hexosaminidases with broad substrate-spectrum (IBS-Hex) are the homologues of human β-N-acetyl-D-hexosaminidase A/B (HsHex A/ B). These enzymes are distributed in most insect species and vary in physiological roles.
Fengyi Liu, Tian Liu, Mingbo Qu, Qing Yang
doaj  

Studies on N-acetal-beta-D-hexosaminidases in human placenta

, 1978
The distribution, biosynthesis and secretion of multiple forms of N-acetyl-B-D-hexosaminidase have been studied in first trimester and term human placentas. Hexosaminidases A, B, I1 and were identified in extracts from whole term placental tissue and the
Douglas, Gordon Charles
core  

Purificação e caracterização parcial de duas N-acetil-ß-hexosaminidases do Equinoderma marinho Echinometra lucunter [PDF]

, 2006
Two b-N-acetylhexosaminidases (F11 e F15) were purified from Echinometra lucunter gonads extracts. The purified enzymes were obtained using ammonium sulfate fractionation, followed by gel filtration chromatographies (Sephacryl S-200, Sephadex G-75 and ...
Lima, Ádila Lorena Morais
core  

Synthesis of 2-acetamido-1,2-dideoxy-d-galacto-nojirimycin [DGJNAc] from d-glucuronolactone: the first sub-micromolar inhibitor of α-N-acetylgalactosaminidases

, 2010
2-Acetamido-1,2-dideoxy-d-galacto-nojirimycin [DGJNAc], prepared in 20% overall yield from d-glucuronolactone, is the first potent competitive sub-micromolar inhibitor of α-N-acetyl-galactosaminidases (Ki 0.081 μM from chicken liver, Ki 0.136 μM from ...
Glawar, AFG, Wilson, FX, Fleet, George, Jia, Y-M, Adachi, I, Crabtree, E, Butters, TD, Best, D, Yu, C-Y, Kato, A, Wang, W-B, Fleet, GWJ, Chairatana, P   +12 more
core   +1 more source