Results 141 to 150 of about 2,313 (194)

Selective Trihydroxylated Azepane Inhibitors of NagZ, a Glycosidase Involved in Pseudomonas Aeruginosa Resistance to β-lactam Antibiotics [PDF]

, 2017
and multiple more authors, and multiple more authors, Benzie, Graeme R., Benzie, Graeme R., Bouquet, Jaufret, Bouquet, Jaufret, King, Dustin T., King, Dustin T., Vadlamani, Grishma, Vadlamani, Grishma, Vocadlo, David J., Vocadlo, David J.   +11 more
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A metaproteomic analysis of the piglet fecal microbiome across the weaning transition. [PDF]

Front Microbiol
Rivera I, Harlow K, Cole RN, O'Meally R, Garrett W, Xiong W, Oliver W, Wells JE, Summers KL, Chhetri N, Postnikova O, Rempel L, Crouse M, Neville B, Davies CP.   +14 more
europepmc   +1 more source

A multiplexed targeted method for profiling of serum gangliosides and glycosphingolipids: application to GM2-gangliosidosis. [PDF]

Anal Bioanal Chem
Kim J, Byeon SK, Oglesbee D, Schultz MJ, Matern D, Pandey A.   +5 more
europepmc   +1 more source

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Electrophoretic study of hexosaminidases. Hexosaminidase C

Clinica Chimica Acta, 1973
Abstract Electrophoresis on cellulose acetate of extracts of various human tissues showed consistently, in addition to the already known hexosaminidases A and B, a faster band called hexosaminidase C. Its relative intensity was greater in extracts from embryonic than from adult tissues.
L, Poenaru, J C, Dreyfus
exaly   +3 more sources

Human urinary N-acetyl-β-hexosaminidases

Biochimica Et Biophysica Acta - Biomembranes, 1973
Analysis of urinary N-acetyl-β-hexosaminidases (β-2-acetamido-2-deoxy-d-glucoside acetamidodeoxyglucohydrolase, EC 3.2.1.30) by DEAE-cellulose chromatography revealed the presence of both the A and B isozymes and a new minor component designated N-acetyl-β-hexosaminidase M.
E E, Grebner, J, Tucker
exaly   +3 more sources

Hexosaminidase assays

Glycoconjugate Journal, 2008
beta-Hexosaminidases (EC 3.2.1.52) are lysosomal enzymes that remove terminal beta-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from a number of glycoconjugates. Reliable assay systems are particularly important for the diagnosis of a family of lysosomal storage disorders, the GM2 gangliosidoses that result from inherited
Michaela, Wendeler, Konrad, Sandhoff
openaire   +2 more sources

The tissue distribution of hexosaminidase S and hexosaminidase C

Annals of Human Genetics, 1977
SUMMARYThe proportion of hex S to hex C in normal and Sandhoff's fibroblasts was determined to be between 1:1 and 1:2 by differential staining of hex S at pH 4.4 with 4‐methylumbelliferyl‐β‐N‐acetylgalactosaminide and of hex C at pH 7.0 with 4‐methylumbelliferyl‐β‐N‐acetylglucosaminide.
E, Beutler, W, Kuhl
openaire   +2 more sources

Affinity purification of hexosaminidases

Journal of Biochemical and Biophysical Methods, 1987
Hexosaminidases A and B were purified by affinity chromatography from normal gastric mucosa, after preliminary separation of isozymes by anion exchange chromatography. Heparin and mannosamine were coupled to Sepharose 4B and used as affinity matrices and the purified enzymes were found to be homogeneous when analysed by polyacrylamide slab gel ...
P, Sankaranarayanan, S, Chandrasekaran, R, Puvanakrishnan, S C, Dhar, S, Gopalakrishnan, N, Rangabashyam   +5 more
openaire   +2 more sources

Subunit structure of human hexosaminidase verified: interconvertibility of hexosaminidase isozymes

Nature, 1975
Two major and several minor isozymes of hexosaminidase (Hex) exist in human tissues. In Tay-Sachs disease Hex A is missing but the activity of Hex B is increased. In Sandhoff's disease, both Hex A and Hex B are lacking; the residual activity represents increased amounts of a normal minor isozyme, Hex S.
E, Beutler, W, Kuhl
openaire   +2 more sources