Interaction of substituted hexose analogues with the Trypanosoma brucei hexose transporter [PDF]
Biochemical Pharmacology, 2004 Glucose metabolism is essential for survival of bloodstream form Trypanosoma brucei subspecies which cause human African trypanosomiasis (sleeping sickness). Hexose analogues may represent good compounds to inhibit glucose metabolism in these cells. Delivery of such compounds to the parasite is a major consideration in drug development.
Laurent, Azema +11 more
openaire +3 more sources
The Hexose efflux from the peeled grape berry [PDF]
OENO One, 2019 Aim: The transport of sugars into grape berry mesocarp cells across the plasma and vacuolar membranes after onset of ripening is a complex process. Elements of the sugar transport mechanism may be assessed by exposing the mesocarp cells and investigating
Predrag Nenad Božović +2 more
doaj +2 more sources
Effects of Active Hexose Correlated Compound on the Seasonal Variations of Immune Competence in Healthy Subjects [PDF]
Journal of Evidence-Based Complementary & Alternative Medicine, 2015 The aim of this study was to evaluate the effects of active hexose correlated compound intake on the immune competence in healthy volunteers. Thirty-four subjects were randomized to receive placebo or active hexose correlated compound at 1.0 g/d for 4 ...
Jun Takanari +5 more
doaj +2 more sources
On the evolution of hexose transporters in kinetoplastid Protozoans [corrected]. [PDF]
PLoS ONE, 2012 Glucose, an almost universally used energy and carbon source, is processed through several well-known metabolic pathways, primarily glycolysis. Glucose uptake is considered to be the first step in glycolysis.
Claudio Alejandro Pereira +1 more
doaj +3 more sources
Peculiarities of hexose transport and catabolite repression regulation by hexose sensors HpGcr1 and HpHxs1 in the yeast Hansenula polymorpha [PDF]
Біологічні студії, 2012 In the yeasts, as in the majority of microorganisms, glucose is the main source of carbon and energy, as well as a key effector molecule involved in transcriptional regulation.
O. G. Stasyk +4 more
doaj +2 more sources
Influence of Two Hexose Transporters on Substrate Affinity and Pathogenicity in Magnaporthe oryzae [PDF]
MicroorganismsHexose transporters (HXT) play a crucial role in the pathogenicity of Magnaporthe oryzae, serving not only as key facilitators for acquiring and transporting sugar nutrients to support pathogen development, but also as sugar sensors which receive ...
Tinghong Huang +7 more
doaj +2 more sources
Arsenic trioxide uptake by hexose permeases in Saccharomyces cerevisiae [PDF]
, 2021 Arsenic trioxide is a toxic metalloid and carcinogen that is also used as an anticancer drug, and for this reason it is important to identify the routes of arsenite uptake by cells.
Rosen, Barry P. +2 more
core +1 more source
Re-examination of hexose-transporter inhibition and labelling by hexose isothiocyanates [PDF]
Biochemical Journal, 1987 We have re-examined hexose-transport inhibition by hexose isothiocyanates and find that the inhibition is incomplete, probably because of decomposition of the reagent. The inhibition type is ‘mixed’, because hexose-transporter ligands such as maltose and cytochalasin B only give partial protection from inhibition.
W D, Rees, J, Gliemann, G D, Holman
openaire +2 more sources
Life cycle studies of the hexose transporter of Plasmodiumspecies and genetic validation of their essentiality [PDF]
, 2010 A Plasmodium falciparum hexose transporter (PfHT) has previously been shown to be a facilitative glucose and fructose transporter. Its expression in Xenopus laevis oocytes and the use of a glucose analogue inhibitor permitted chemical validation of PfHT ...
Tewari, R +20 more
core +1 more source
Frontiers in Plant Science, 2016 Phloem osmolality and its components are involved in basic cell metabolism, cell growth, and in various physiological processes including the ability of living cells to withstand drought and frost.
Anna eLintunen +26 more
doaj +1 more source