Results 51 to 60 of about 30,451 (254)

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

Preparation one of prodrug and study its effect on some biochemical parameters at blood serum [PDF]

Kirkuk Journal of Science, 2016
This study included synthesis of Tri [2(4-isobuty phenyl) propionyl ] glycerate afforded by reaction of Glycerol with Ibuprofen. The purification of the synthesized derivative was established by (TLC) and column chromatography while the structure ...
F. S. Abdul-Razzak, D. M.Najim
doaj   +1 more source

All You Can Eat Yeast: Substituting Hexose Transporters With AtSWEET7 Alleviates Glucose Repression, Enabling Simultaneous Utilization of Sugars in Renewable Feedstocks

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Yeast sugar transporters have highly evolved for preferential glucose transport, a significant roadblock for utilizing non‐glucose sugars in renewable feedstocks such as lignocellulosic biomass. To enable simultaneous transport of multiple sugars, native hexose transporters were replaced by SWEET7p from Arabidopsis thaliana in engineered ...
Nurzhan Kuanyshev, Degaulle Dai, Jungyeon Kim, Nam Kyu Kang, Ming‐Hsun Cheng, Vijay Singh, Yong‐Su Jin   +6 more
wiley   +1 more source

Fenóis derivados da lignina, carboidratos e aminoaçúcares em serapilheira e solos cultivados com eucalipto em sistemas convencional e fertirrigado

Revista Árvore, 2013
Este estudo teve por objetivo avaliar os teores de fenóis derivados de lignina, carboidratos e aminoaçúcares, bem como o estádio de decomposição e a contribuição de compostos de origens vegetal e microbiana para a matéria orgânica do solo (MOS) em ...
Rodinei Facco Pegoraro, Ivo Ribeiro Silva, Roberto Ferreira Novais, Nairan Felix Barros, Sebastião Fonseca   +4 more
doaj   +1 more source

Slide-agglutination for rapid serological typing of Treponema hyodysenteriae [PDF]

, 1991
A slide agglutination (SA) test was developed to determine the serogroup of isolates of Treponema hyodysenteriae of serogroups A to F. Rabbit antisera which are normally used for serogrouping T.
Hampson, D.J.
core   +2 more sources

Advancing Malic Acid Production of Aspergillus oryzae: Combined Process Optimization and Application of Various Substrates

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In light of climate change and growing resource scarcity, microbial production of organic acids offers a sustainable alternative to fossil‐based chemical synthesis. In this study, malic acid production by Aspergillus oryzae was optimized through cultivation temperature adjustment and biotin supplementation, while organic acid formation from ...
Lukas Hartmann, Anke Neumann, Dirk Holtmann, Björn Vater, Thomas Hahn, Susanne Zibek, Katrin Ochsenreither   +6 more
wiley   +1 more source

Biosynthesis of rare hexoses using microorganisms and related enzymes

Beilstein Journal of Organic Chemistry, 2013
Rare sugars, referred to as monosaccharides and their derivatives that rarely exist in nature, can be applied in many areas ranging from foodstuffs to pharmaceutical and nutrition industry, or as starting materials for various natural products and drug ...
Zijie Li, Yahui Gao, Hideki Nakanishi, Xiaodong Gao, Li Cai   +4 more
doaj   +1 more source

Stereoselective Synthesis of Glycomimetic Amines From Biomass‐Derived Cyrene

European Journal of Organic Chemistry, EarlyView.
2,3,4‐Trideoxy‐2‐mannosamines, including the unsubstituted one, are accessible as the only endo diastereoisomers by reductive amination of the green solvent Cyrene, derived from pyrolysis of cellulose containing waste biomass. The products are useful chiral synthetic intermediate to nitrogenated glycomimetics.
Debora Pratesi, Marta Rigacci, Francesca Cardona, Camilla Matassini, Andrea Goti   +4 more
wiley   +1 more source

Carbohydrate composition of rat intestine surface mucus layer after ceftriaxone treatment [PDF]

The Ukrainian Biochemical Journal, 2016
The epidemiological studies have shown that antibiotic treatment increases the susceptibility to inflammatory bowel disease development. The disturbance of mucus layer integrity might be one of the possible mechanisms. The aim of the present study was to
Yu. V. Holota, Ya. A. Olefir, T. V. Dovbynchuk, G. M. Tolstanova   +3 more
doaj   +1 more source

Synthetic chemical inducers and genetic decoupling enable orthogonal control of the rhaBAD promoter [PDF]

, 2016
External control of gene expression is crucial in synthetic biology and biotechnology research and applications, and is commonly achieved using inducible promoter systems. The E.
Heap, JT, Kelly, C
core   +1 more source