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Heart Failure With Mid-range Ejection Fraction: A Distinctive Subtype or a Transitional Stage?
Heart failure with mid-range ejection fraction (HFmrEF) was first proposed by Lam and Solomon in 2014, and was listed as a new subtype of heart failure (HF) in 2016 European Society of Cardiology guidelines. Since then, HFmrEF has attracted an increasing
Qing Zhou +18 more
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Impact of signs and symptoms on the prognosis of patients with HFmrEF
Abstract Background Worsening of heart failure (HF) symptoms is the leading cause of medical contact and hospitalization of patients with mildly reduced ejection fraction (HFmrEF). The prognostic value of signs and symptoms for patients with HFmrEF is currently unclear.
Zhican Liu +16 more
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Aims Heart failure with mildly reduced ejection fraction (HFmrEF) is associated with a favourable prognosis compared with heart failure (HF) with reduced ejection fraction (EF). We assessed whether left ventricular ejection fraction (LVEF) trajectory can
Robert J.H. Miller +8 more
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Aim. To analyze and compare the clinical, echocardiographic characteristics and serum N-terminal pro-brain natriuretic peptide (NT-proBNP) levels depending on the central cardiometabolic risk factors, with a focus on obesity, in patients with heart ...
E. A. Lyasnikova +7 more
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Are HFpEF and HFmrEF So Different? The Need to Understand Distinct Phenotypes [PDF]
Traditionally, patients with heart failure (HF) are divided according to ejection fraction (EF) threshold more or <50%. In 2016, the ESC guidelines introduced a new subgroup of HF patients including those subjects with EF ranging between 40 and 49% called heart failure with midrange EF (HFmrEF).
Palazzuoli A., Beltrami M.
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Heart Failure with Mid-range Ejection Fraction——a Comprehension of the Disease [PDF]
Heart failure is the final main battlefield of various cardiovascular diseases with huge harm, which can cause all kinds of arrhythmias and even sudden cardiac death. The 2016 ESC guidelines formally define heart failure with mid-range ejection fraction (
RUAN Zheng, HUANG Jianyu, JIANG Wencai, CHEN Meixiang, QIN Changyu, XU Lin
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Acute decompensated heart failure (ADHF) is one of the most common causes of hospital admission for cardiovascular diseases. ADHF often affects the elderly population, is associated with high morbidity, admission rate and mortality. Pulmonary congestion (
Hui Zhang +3 more
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Heart failure with mildly reduced ejection fraction (HFmrEF) is associated with comparable poor outcomes as other subtypes of heart failure and remains a medical unmet need due to the paucity of effective therapies. According to large cardiovascular (CV)
Xizi Shen, Xingping Shen
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Mechanisms and outcomes of heart failure: from HFpEF, HFmrEF, and HFrEF to transplantation [PDF]
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