Results 71 to 80 of about 6,247 (199)

Refining Residual Ischemic Stroke Risk in Anticoagulated Atrial Fibrillation Using Index Outpatient LA Diameter: The CHA2DS2‐VALa Score

Journal of Cardiovascular Electrophysiology, EarlyView.
In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür, Emin Koyun, Gülşen Genç Tapar, Kayıhan Karaman, Metin Karayakali, Ataç Çelik, Uğur Kulu, Yasin Taşkin   +7 more
wiley   +1 more source

Established and emerging pharmacologic options and unmet needs in HFpEF and HFmrEF

ESC Heart Failure
Abstract A decline in mortality due to heart failure (HF) with reduced ejection fraction (HFrEF) has been attributed to effective guideline-directed medical therapies. But few effective therapies are available for HF with preserved ejection fraction (HFpEF), despite a high burden of HF events, or for HF with mildly reduced ejection ...
Andrew J Sauer, Jozine M ter Maaten, Gianluigi Savarese   +2 more
openaire   +2 more sources

Mortality and Morbidity in HFrEF, HFmrEF, and HFpEF Patients with Diabetes in the Middle East

Oman Medical Journal, 2020
We sought to estimate the mortality and morbidity in diabetic acute heart failure (AHF) patients stratified by left ventricular ejection fraction.We analyzed the data of patients with AHF from seven Middle Eastern countries (Bahrain, Oman, Yemen, Kuwait, UAE, Qatar, and Saudi Arabia) from February to November 2012, who were enrolled in a multinational ...
Mohammed Al-Jarallah, Rajesh Rajan, Ibrahim Al-Zakwani, Raja Dashti, Bassam Bulbanat, Mustafa Ridha, Kadhim Sulaiman, Alawi A. Alsheikh-Ali, Prashanth Panduranga, Khalid F. AlHabib, Jassim Al Suwaidi, Wael Al-Mahmeed, Hussam AlFaleh, Abdelfatah Elasfar, Ahmed Al-Motarreb, Nooshin Bazargani, Nidal Asaad, Haitham Amin   +17 more
openaire   +3 more sources

Echocardiographic and Clinical Correlates of Ejection Fraction Among 2000 Patients with Heart Failure in Western Saudi Arabia

International Journal of General Medicine, 2020
Ahmed Hussein Subki,1 Mohammed Ali Almalki,2 Nadeem Shafique Butt,3 Mohammed Saad Alsallum,4 Hatim Mashan Almutairi,5 Hazim Abdulkarim Khatib,6 Abdulrahman Mousa Alzahrani,6 Abdullah Salem Babaker,6 Firas Abdulrahman Addas,6 Abdullah Abdulfattah Mashat,7
Subki AH, Almalki MA, Butt NS, Alsallum MS, Almutairi HM, Khatib HA, Alzahrani AM, Babaker AS, Addas FA, Mashat AA, Jad AY, Zafar ZA, Nogali BW, Alghamdi AA, Alghamdi NA, Dakhakhni MF, Asaad OT, Alghalayini KW   +17 more
doaj  

SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic, Jovana Rajkovic, Radmila Novakovic, Javad Sharifi‐Rad, Daniela Calina   +4 more
wiley   +1 more source

Characteristics of patients with chronic heart failure with mildly reduced ejection fraction: clinical and demographic aspect

Acta Biomedica Scientifica
Introduction. A new class of chronic heart failure (CHF) has been identified recently – heart failure with mildly reduced left ventricular ejection fraction (HFmrEF). The determinants and outcomes of this phenotype are still being clarified.The aim.
M. T. Duishenalieva, A. G. Polupanov, F. T. Rysmatova, E. Zh. Myrzabekova, N. E. Esenbekova, N. Ch. Cholponbekova, E. Sh. Altymyshova, A. T. Arykova, N. B. Cheskidova, E. D. Djyshambaev   +9 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Agonists and the Incidence of Atrial Fibrillation in Obese Patients With Heart Failure With Preserved Ejection Fraction and No Diabetes

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Among obese, non‐diabetic patients with HFpEF, GLP‐1 RA therapy was not significantly associated with incident atrial fibrillation but was associated with lower all‐cause mortality. Prospective studies are needed to clarify the potential role of GLP‐1 RAs in AF prevention. ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) reduce
Farah Rassam, Esteban Kosak Lopez, Sarah Sass, Thitiphan Srikulmontri, Evan Isaacs, John Malin, Phuuwadith Wattanachayakul, Olayinka Afolabi‐Brown   +7 more
wiley   +1 more source

Circulating ECM proteins decorin and alpha-L-iduronidase differentiate ATTRwt-CM from ATTRwt-negative HFpEF/HFmrEF [PDF]

Aims: Wild-type transthyretin cardiac amyloidosis (ATTRwt-CM) is an under-recognized aetiology of heart failure (HF), necessitating early detection for timely treatment.
Bijzet, Johan; id_orcid, Tingen, Hendrea S.A., van Essen, Bart J.; id_orcid, Baumhove, Lukas; id_orcid, Voors, Adriaan A., Hazenberg, Bouke P.C.; id_orcid, Meems, Laura M.G., Nienhuis, Hans L.A., van Veldhuisen, Dirk J., Slart, Riemer H.J.A., Markousis-Mavrogenis, George, Berends, Milou; id_orcid, Tubben, Alwin, van der Meer, Peter   +13 more
core   +1 more source

Correlation of the decrease in exercise tolerance with the ventilation and gas exchange disturbances in patients with various phenotypes of chronic heart failure

Клинический разбор в общей медицине
Aim. To assess parameters of ventilation and gas exchange and determine the factors associated with the peak oxygen consumption levels in patients with various phenotypes of chronic heart failure (CHF). Methods. The study was focused on further analysis
Yulia L. Begrambekova, Nino A. Karanadze, Artem N. Zadoia, Elena M. Seredenina, Alina G. Plisyuk   +4 more
doaj   +1 more source

Perturbations of pulsatile hemodynamics and clinical outcomes in patients with acute heart failure and reduced, mid-range or preserved ejection fraction.

PLoS ONE, 2019
BackgroundHeart failure with mid-range ejection fraction (HFmrEF) has been proposed as a new phenotype of heart failure. We therefore investigated the pulsatile hemodynamic characteristics and outcomes in patients with HFmrEF, in comparison with those ...
Wei-Ming Huang, Shih-Hsien Sung, Wen-Chung Yu, Hao-Min Cheng, Chi-Jung Huang, Chao-Yu Guo, Dai-Yin Lu, Ching-Wei Lee, Chen-Huan Chen   +8 more
doaj   +1 more source