Results 11 to 20 of about 30,234 (198)
Nature Network Boston, 2023 In the STEP-HFpEF trial, semaglutide improved symptoms, physical limitations and exercise function and reduced body weight in patients with obesity phenotype of heart failure and preserved ejection fraction (HFpEF).
B. Borlaug +27 more
semanticscholar +1 more source
Heart Failure with Perserved Ejection Fraction Current Diagnostic and Therapeutic Approaches
Рациональная фармакотерапия в кардиологии, 2021 Heart failure with preserved ejection fraction (HFpEF) is a syndrome associated with high morbidity and mortality rates. Little progress has been in the treatment of this condition since its introduction some 30 years ago.
A. A. Shchendrygina +9 more
doaj +1 more source
Cardiovascular Diabetology, 2023 Background Epicardial adipose tissue (EAT) accumulation is associated with multiple cardiometabolic risk factors and prognosis of heart failure with preserved ejection fraction (HFpEF). The correlation between EAT density and cardiometabolic risk and the
Jie Liu +10 more
semanticscholar +1 more source
Cardiometabolic HFpEF: NASH of the Heart
Circulation, 2023 Identifying the correct clinical and pathophysiological framework for complex syndromes is often challenging. With heart failure with preserved ejection fraction (HFpEF), we probably got off on the wrong foot.
Federico Capone +2 more
semanticscholar +1 more source
The NO-cGMP-PKG Axis in HFpEF: From Pathological Mechanisms to Potential Therapies
Aging and Disease, 2023 Heart failure with preserved ejection fraction (HFpEF) accounts for almost half of all heart failure (HF) cases worldwide. Unfortunately, its incidence is expected to continue to rise, and effective therapy to improve clinical outcomes is lacking ...
Zhulan Cai +5 more
semanticscholar +1 more source
Deciphering the Dilemma: Anticoagulation for Heart Failure With Preserved Ejection Fraction (HFpEF)
Cureus, 2023 Impairment in ventricular relaxation and preserved left ventricular ejection fraction are the two main features of heart failure with preserved ejection fraction (HFpEF) a difficult clinical condition.
Fnu Jyotsna +10 more
semanticscholar +1 more source
Myeloid Cell Derived IL1β Contributes to Pulmonary Hypertension in HFpEF
Circulation Research, 2023 BACKGROUND: Pulmonary hypertension (PH) in heart failure with preserved ejection fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH-HFpEF are poorly understood.
Vineet Agrawal +17 more
semanticscholar +1 more source
The Concept of "Heart Failure with Preserved Ejection Fraction": Time for a Critical Reappraisal
Reviews in Cardiovascular Medicine, 2023 Heart failure with preserved ejection fraction (HFpEF) is frequently observed in elderly physically deconditioned subjects, mainly women with hypertension, obesity, glucose intolerance/diabetes, atrial fibrillation, anaemia, coronary artery disease ...
Gabriele Fragasso
doaj +1 more source
Obesity in HFpEF with and without diabetes - Risk factor or innocent bystander?
European Journal of Preventive Cardiology, 2023 BACKGROUND Heart failure with preserved ejection fraction (HFpEF) is a condition that commonly coexists with type 2 diabetes mellitus (T2DM) and obesity. Whether the obesity-related survival benefit generally observed in HFpEF extends to individuals with
Suriya Prausmüller +12 more
semanticscholar +1 more source
SGLT2 inhibitors: a new pillar of the heart failure regimen
Reviews in Cardiovascular Medicine, 2021 Initially intended as an adjunct treatment for type 2 diabetes mellitus (T2DM), SGLT2-inhibitors (SGLT2i) have transformed into an unexpected pillar of the heart failure (HF) regimen.
Travis DeSa +1 more
doaj +1 more source