Results 21 to 30 of about 30,284 (243)
Cardiometabolic HFpEF: Mechanisms and Therapies [PDF]
CardioMetabolic Syndrome Journal, 2021 Heart failure with preserved ejection fraction (HFpEF) accounts for at least half of all patients with heart failure (HF) and is projected to be the most common form of HF in the near feature. HFpEF, characterized by high morbidity and mortality, poses an enormous medical and societal burden and lacks evidence-based therapies.
Gabriele G. Schiattarella +1 more
openaire +2 more sources
The NO-cGMP-PKG Axis in HFpEF: From Pathological Mechanisms to Potential Therapies
Aging and Disease, 2023 Heart failure with preserved ejection fraction (HFpEF) accounts for almost half of all heart failure (HF) cases worldwide. Unfortunately, its incidence is expected to continue to rise, and effective therapy to improve clinical outcomes is lacking ...
Zhulan Cai +5 more
semanticscholar +1 more source
The many faces of HFPEF: insights from the CMR substudy of DIAMOND-HFPEF [PDF]
Journal of Cardiovascular Magnetic Resonance, 2015 Background Heart failure with preserved ejection fraction (HFPEF) carries significant mortality and morbidity. This population is characterized by marked heterogeneity. To date, this population has been poorly phenotyped and it remains unclear what proportion may have evidence of myocardial infarction (MI), undiagnosed cardiomyopathies or phenocopies ...
Adrian S. H. Cheng +7 more
openaire +2 more sources
Deciphering the Dilemma: Anticoagulation for Heart Failure With Preserved Ejection Fraction (HFpEF)
Cureus, 2023 Impairment in ventricular relaxation and preserved left ventricular ejection fraction are the two main features of heart failure with preserved ejection fraction (HFpEF) a difficult clinical condition.
Fnu Jyotsna +10 more
semanticscholar +1 more source
Myeloid Cell Derived IL1β Contributes to Pulmonary Hypertension in HFpEF
Circulation Research, 2023 BACKGROUND: Pulmonary hypertension (PH) in heart failure with preserved ejection fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH-HFpEF are poorly understood.
Vineet Agrawal +17 more
semanticscholar +1 more source
The Concept of "Heart Failure with Preserved Ejection Fraction": Time for a Critical Reappraisal
Reviews in Cardiovascular Medicine, 2023 Heart failure with preserved ejection fraction (HFpEF) is frequently observed in elderly physically deconditioned subjects, mainly women with hypertension, obesity, glucose intolerance/diabetes, atrial fibrillation, anaemia, coronary artery disease ...
Gabriele Fragasso
doaj +1 more source
Obesity in HFpEF with and without diabetes - Risk factor or innocent bystander?
European Journal of Preventive Cardiology, 2023 BACKGROUND Heart failure with preserved ejection fraction (HFpEF) is a condition that commonly coexists with type 2 diabetes mellitus (T2DM) and obesity. Whether the obesity-related survival benefit generally observed in HFpEF extends to individuals with
Suriya Prausmüller +12 more
semanticscholar +1 more source
SGLT2 inhibitors: a new pillar of the heart failure regimen
Reviews in Cardiovascular Medicine, 2021 Initially intended as an adjunct treatment for type 2 diabetes mellitus (T2DM), SGLT2-inhibitors (SGLT2i) have transformed into an unexpected pillar of the heart failure (HF) regimen.
Travis DeSa +1 more
doaj +1 more source
Anatolian Journal of Cardiology, 2023 Background: Heart failure with preserved ejection fraction is a complex and heterogeneous clinical syndrome, poses significant diagnostic challenges.
Gurbet Özge Mert +19 more
doaj +1 more source
Медицинский вестник Юга России, 2021 Type 2 diabetes mellitus is known to increase the risk of the development of heart failure with preserved ejection fraction and worsen its symptoms. To date, no specific treatment has been shown to reduce morbidity and mortality in patients with heart ...
A. A. Borisov +2 more
doaj +1 more source