SGLT2 inhibitors: a new pillar of the heart failure regimen
Initially intended as an adjunct treatment for type 2 diabetes mellitus (T2DM), SGLT2-inhibitors (SGLT2i) have transformed into an unexpected pillar of the heart failure (HF) regimen.
Travis DeSa +1 more
doaj +1 more source
Background: Heart failure with preserved ejection fraction is a complex and heterogeneous clinical syndrome, poses significant diagnostic challenges.
Gurbet Özge Mert +19 more
doaj +1 more source
Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme [PDF]
Aims We investigated the association between worsening renal function (WRF) that occurs during renin–angiotensin–aldosterone system inhibition initation and outcome in heart failure (HF) patients with preserved ejection fraction (HFPEF) and compared ...
Brenner +21 more
core +1 more source
Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction [PDF]
Aims: Impaired left ventricular diastolic function leading to elevated left atrial pressures, particularly during exertion, is a key driver of symptoms and outcomes in heart failure with preserved ejection fraction (HFpEF). Insertion of an interatrial
Aytug, H +22 more
core +2 more sources
Our goal was to characterize a cohort of heart failure patients with and without COVID-19 in terms of demographics, comorbid conditions, treatment regimens, lab test results and outcome.
Vintilă Ana-Maria +9 more
doaj +1 more source
Isosorbide dinitrate, with or without hydralazine, does not reduce wave reflections, left ventricular hypertrophy, or myocardial fibrosis in patients with heart failure with preserved ejection fraction [PDF]
Background-Wave reflections, which are increased in patients with heart failure with preserved ejection fraction, impair diastolic function and promote pathologic myocardial remodeling.
Akers, Scott +13 more
core +1 more source
Shengen Liao,1,* Yuan Tang,1,* Xin Yue,1 Rongrong Gao,1 Wenming Yao,1 Yanli Zhou,1 Haifeng Zhang2,3 1Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, 210029, People’s ...
Liao S +6 more
doaj
Tackling metabolic defects in HFpEF [PDF]
Rongling Wang, Gabriele G. Schiattarella
openalex +4 more sources
Acute decompensated heart failure (ADHF) is one of the most common causes of hospital admission for cardiovascular diseases. ADHF often affects the elderly population, is associated with high morbidity, admission rate and mortality. Pulmonary congestion (
Hui Zhang +3 more
doaj +1 more source
Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension. [PDF]
Pulmonary arterial compliance (PAC), invasively assessed by the ratio of stroke volume to pulmonary arterial (PA) pulse pressure, is a sensitive marker of right ventricular (RV)-PA coupling that differs across the spectrum of pulmonary hypertension (PH ...
Bhattacharya, Priyanka T. +15 more
core +2 more sources

