Results 31 to 40 of about 32,390 (296)
Медицинский вестник Юга России, 2021 Type 2 diabetes mellitus is known to increase the risk of the development of heart failure with preserved ejection fraction and worsen its symptoms. To date, no specific treatment has been shown to reduce morbidity and mortality in patients with heart ...
A. A. Borisov +2 more
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New aspects in cardiorenal syndrome and HFpEF
Clinical Kidney Journal, 2022 Cardiorenal syndrome (CRS) is a complex disease in which the heart and kidneys are simultaneously affected, and subsequently, the malfunction of one organ promotes the deterioration of the other. Heart failure (HF) with preserved ejection fraction (HFpEF)
A. Méndez +3 more
semanticscholar +1 more source
Development and Challenges of Pre-Heart Failure with Preserved Ejection Fraction
Reviews in Cardiovascular Medicine, 2023 Pre-heart failure with preserved ejection fraction (Pre-HFpEF) is a critical link to the development of heart failure with preserved ejection fraction (HFpEF). Early recognition and early intervention of pre-HFpEF will halt the progression of HFpEF. This
Guoju Dong
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Targeting Mitochondria-Inflammation Circuit by β-Hydroxybutyrate Mitigates HFpEF
Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: Over 50% of patients with heart failure have preserved ejection fraction (HFpEF), rather than reduced ejection fraction.
Yan Deng +18 more
semanticscholar +1 more source
Reviews in Cardiovascular MedicineHeart failure (HF) is the predominant terminal stage and the leading cause ofmortality in cardiac disease. Heart failure with preserved ejection fraction(HFpEF) affects roughly 50% of HF patients globally.
Qiuxuan Li +5 more
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Do we need a definition of acute heart failure with preserved ejection fraction?
Annals of Medicine, 2021 Heart failure with preserved ejection fraction (HFpEF) might soon become the most prevalent type of acute heart failure. Still, despite more than 30 years of research on HFpEF, not only do we lack specific treatment, but also a generally accepted ...
Agnieszka Kapłon-Cieślicka +1 more
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Dual SGLT-1 and SGLT-2 inhibition improves left atrial dysfunction in HFpEF
Cardiovascular Diabetology, 2021 Background Sodium–glucose linked transporter type 2 (SGLT-2) inhibition has been shown to reduce cardiovascular mortality in heart failure independently of glycemic control and prevents the onset of atrial arrhythmias, a common co-morbidity in heart ...
D. Bode +14 more
semanticscholar +1 more source
European Heart JournalBackground and Aims In the STEP-HFpEF trial programme, treatment with semaglutide resulted in multiple beneficial effects in patients with obesity-related heart failure with preserved ejection fraction (HFpEF).
Sanjiv J. Shah +15 more
semanticscholar +1 more source
Cells, 2020 Heart failure (HF) is the most rapidly growing cardiovascular health burden worldwide. HF can be classified into three groups based on the percentage of the ejection fraction (EF): heart failure with reduced EF (HFrEF), heart failure with mid-range—also ...
S. Simmonds +3 more
semanticscholar +1 more source
Empagliflozin Preserves Skeletal Muscle Function in a HFpEF Rat Model
International Journal of Molecular Sciences, 2022 Besides structural alterations in the myocardium, heart failure with preserved ejection fraction (HFpEF) is also associated with molecular and physiological alterations of the peripheral skeletal muscles (SKM) contributing to exercise intolerance often ...
E. Winzer +11 more
semanticscholar +1 more source