STEP-HFpEF: A Large Step for HFpEF. [PDF]
Journal of the American College of CardiologyContains fulltext : 307714.pdf (Publisher’s version ) (Open Access)
Kimmenade, R.R.J. van, Hassing, C.
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Novel pathways of heart failure with preserved ejection fraction [PDF]
, 2016 INTRODUCTION: Diastolic heart failure (HF) i.e., HF with preserved ejection fraction (HFpEF) accounts for ~50% of all clinical HF presentations; but unlike systolic HF i.e., HF with reduced ejection fraction (HFrEF), there are no evidenced based ...
Li, Shanpeng
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Do we need a definition of acute heart failure with preserved ejection fraction?
Annals of Medicine, 2021 Heart failure with preserved ejection fraction (HFpEF) might soon become the most prevalent type of acute heart failure. Still, despite more than 30 years of research on HFpEF, not only do we lack specific treatment, but also a generally accepted ...
Agnieszka Kapłon-Cieślicka +1 more
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International Journal of Molecular Sciences, 2022 (1) Background: Heart failure with preserved ejection fraction (HFpEF) is a major subtype of HF with no effective treatments. Mitochondrial dysfunctions relevant to the imbalance of fusion and fission occur in HFpEF.
J. Shou, Yunlong Huo
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Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension. [PDF]
, 2019 Pulmonary arterial compliance (PAC), invasively assessed by the ratio of stroke volume to pulmonary arterial (PA) pulse pressure, is a sensitive marker of right ventricular (RV)-PA coupling that differs across the spectrum of pulmonary hypertension (PH ...
Bhattacharya, Priyanka T. +15 more
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Interrelation between heart failure with preserved ejection fraction and renal impairment [PDF]
Reviews in Cardiovascular Medicine, 2022 Heart failure with preserved ejection fraction (HFpEF) and chronic kidney disease (CKD) are global diseases of increasing prevalence and are frequent co-diagnoses.
Jennifer Ruth Joslin +2 more
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Cells, 2020 Heart failure (HF) is the most rapidly growing cardiovascular health burden worldwide. HF can be classified into three groups based on the percentage of the ejection fraction (EF): heart failure with reduced EF (HFrEF), heart failure with mid-range—also ...
S. Simmonds +3 more
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Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events
Scientific Reports, 2022 There is increasing evidence that HFpEF is a heterogeneous clinical entity and distinct molecular pathways may contribute to pathophysiology. Leveraging unbiased proteomics to identify novel biomarkers, this study seeks to understand the underlying ...
J. Regan +14 more
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Journal of the American College of Cardiology, 2014 Among the numerous comorbidities that can confound the diagnosis of heart failure with a preserved ejection fraction (HFpEF), diabetes is among the most prevalent. Approximately one-third of patients with HFpEF have diabetes [(1,2)][1], and as many as half of patients hospitalized with HFpEF ...
Mathew S. Maurer, Donna M. Mancini
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Interleukin-1 blockade in heart failure with preserved ejection fraction: rationale and design of the Diastolic Heart Failure Anakinra Response Trial 2 (D-HART2) [PDF]
, 2017 Heart failure with preserved ejection fraction (HFpEF) now accounts for the majority of con-firmed HF cases in the United States. However, there are no highly effective evidence-basedtreatments currently available for these patients.
Abbate, Antonio +10 more
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