Results 61 to 70 of about 32,390 (296)

Empagliflozin Improves Diastolic Function in HFpEF by Restabilizing the Mitochondrial Respiratory Chain

Circulation: Heart Failure
BACKGROUND: Clinical studies demonstrated beneficial effects of sodium-glucose-transporter 2 inhibitors on the risk of cardiovascular death in patients with heart failure with preserved ejection fraction (HFpEF).
Antje Schauer, V. Adams, S. Kämmerer, E. Langner, A. Augstein, P. Barthel, Anita Männel, Gunar Fabig, P. Alves, Mario Günscht, A. El-Armouche, T. Müller-Reichert, Axel Linke, E. Winzer   +13 more
semanticscholar   +1 more source

Exercise-Stress Real-time Cardiac Magnetic Resonance Imaging for Non-Invasive Characterisation of Heart Failure with Preserved Ejection Fraction: The HFpEF Stress Trial.

Circulation, 2021
Background: Right heart catheterisation (RHC) using exercise-stress is the reference standard for the diagnosis of heart failure with preserved ejection fraction (HFpEF) but carries the risk of the invasive procedure.
S. Backhaus, T. Lange, Elisabeth F. George, K. Hellenkamp, R. Gertz, Marcus Billing, R. Wachter, M. Steinmetz, S. Kutty, U. Raaz, J. Lotz, T. Friede, M. Uecker, G. Hasenfuss, T. Seidler, A. Schuster   +15 more
semanticscholar   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Evaluation of Cardiorenal Metabolic Syndrome in Patients with Heart Failure with Preserved Ejection Fraction. How Aware Are We?

Sakarya Tıp Dergisi
Aim: Despite the prevalence of cardiorenal metabolic diseases (CRMD) in heart failure with preserved ejection fraction (HFpEF) patients and their significant complications, they are thought to be under-recognized and under-screened.
Dilan Damla Ozturk, Fatih Necip Arıcı, Cigdem Erhan, Bektaş Işık, Mehmet Can Erişen, Berçem Berent Kaya, Ugur Can Izlimek, Cahit Dincer, Ahmet Gazi Mustan, Çisem Yılmaz, Tayyibe Saler, Hilmi Erdem Sümbül, Erdinc Gulumsek, Hüseyin Ali Öztürk   +13 more
doaj   +1 more source

Exercise training ameliorates myocardial phenotypes in heart failure with preserved ejection fraction by changing N6-methyladenosine modification in mice model

Frontiers in Cell and Developmental Biology, 2022
Heart failure with preserved ejection fraction (HFpEF) shows complicated and not clearly defined etiology and pathogenesis. Although no pharmacotherapeutics have improved the survival rate in HFpEF, exercise training has become an efficient intervention ...
Kai Liu, Kai Liu, Kai Liu, Wenhao Ju, Wenhao Ju, Wenhao Ju, Shengrong Ouyang, Shengrong Ouyang, Zhuo Liu, Zhuo Liu, Feng He, Feng He, Jingyi hao, Hongyan Guan, Hongyan Guan, Jianxin Wu, Jianxin Wu, Jianxin Wu, Jianxin Wu, Jianxin Wu   +19 more
doaj   +1 more source

Empagliflozin inhibits increased Na influx in atrial cardiomyocytes of patients with HFpEF

Cardiovascular Research
Aims Heart failure with preserved ejection fraction (HFpEF) causes substantial morbidity and mortality. Importantly, atrial remodelling and atrial fibrillation are frequently observed in HFpEF.
M. Trum, J. Riechel, E. Schollmeier, S. Lebek, P. Hegner, K. Reuthner, Silvia Heers, K. Keller, M. Wester, S. Klatt, N. Hamdani, Z. Provaznik, C. Schmid, L. Maier, M. Arzt, S. Wagner   +15 more
semanticscholar   +1 more source

A prospective STudy using invAsive haemodynamic measurements foLLowing catheter ablation for AF and early HFpEF: STALL AF‐HFpEF

European Journal of Heart Failure, 2021
The impact of atrial fibrillation (AF) ablation in early heart failure with preserved ejection fraction (HFpEF) is unknown. Our aim was to determine the impact of AF ablation on symptoms and exercise haemodynamic parameters of early HFpEF.
H. Sugumar, S. Nanayakkara, D. Vizi, L. Wright, D. Chieng, A. Leet, J. Mariani, A. Voskoboinik, S. Prabhu, A. Taylor, J. Kalman, P. Kistler, D. Kaye, L. Ling   +13 more
semanticscholar   +1 more source

Incident heart failure: comparing management and outcome in primary and hospital settings in Western Sweden 2008–2017

ESC Heart Failure, Volume 12, Issue 2, Page 832-838, April 2025.
Abstract Aim Heart failure (HF) is a highly prevalent condition managed in both primary care (PC) and hospital care (HC)‐based settings. HF patients managed in these two settings may differ in their demography, comorbidities and outcomes, so we aimed to compare the patient management in PC and HC in the Västra Götaland Region (VGR) in Sweden.
Xiaojing Chen, Aldina Pivodic, Maria Schaufelberger, Annika Rosengren, Michael Fu   +4 more
wiley   +1 more source

Pediatric Heart Failure Pharmacotherapy: Transformative Insights for the Future

Reviews in Cardiovascular Medicine
This review aims to summarize the status and future directions of pediatric heart failure (HF) pharmacotherapy. Notably, managing HF in children presents unique challenges due to heterogeneous etiologies and a longstanding paucity of pediatric-specific ...
Bibhuti B Das
doaj   +1 more source

Natriuretic Peptide Clearance Receptor (NPR-C) Pathway as a Novel Therapeutic Target in Obesity-Related Heart Failure With Preserved Ejection Fraction (HFpEF) [PDF]

, 2021
Emmanuel E. Egom
openalex   +1 more source