Results 91 to 100 of about 20,461 (225)

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, EarlyView.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Martina Hüttl, Olga Lenčová, Kasin Yadunandam Anandam, Svenja Stomberg, Sönke Behrends, Barbara Szeiffová Bačová, Matúš Sykora, Lisa Dietz, Peter Sandner, Luděk Červenka, Martin Štěrba   +14 more
wiley   +1 more source

Comparative analysis of serum galanin levels in patients with coronary artery disease with and without heart failure with reduced ejection fraction and in individuals without cardiovascular diseases

Кардиоваскулярная терапия и профилактика
Aim. To study the level of the neuro-regulatory peptide galanin in pa­tients with coronary artery disease (CAD) with and without heart failu­re with reduced ejection fraction (HFrEF) in comparison with individuals without cardiovascular disease (CVD ...
Yu. S. Timofeev, A. A. Yafarova, A. F. Sheptulina, A. R. Kiselev, V. A. Metelskaya, N. I. Dubovskaya, O. M. Drapkina   +6 more
doaj   +1 more source

Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities

ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

Decreased endogenous nitric oxide production in acute decompensated heart failure with a reduced ejection fraction

ESC Heart Failure
Aims Heart failure represents a substantial burden to both patients and healthcare systems worldwide. Nitric oxide (NO) dysregulation may play a key role in patients transitioning from chronic to acute heart failure with a reduced ejection fraction ...
Roman Falls, Bing H. Wang, Sara Vogrin, Christopher J. Neil   +3 more
doaj   +1 more source

Empagliflozin and HFrEF

JACC: Basic to Translational Science, 2019
Seungho Jun, Miguel A. Aon, Nazareno Paolocci   +2 more
openaire   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Cardiovascular Autonomic Neuropathy and Indices of Heart Failure in Type 2 Diabetes: The CANCAN Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D). Materials and Methods Two hundred T2D individuals were recruited from two Danish outpatient clinics between 2021–2024. CAN was defined by abnormal cardiovascular autonomic reflex test results.
Jonas R. Schaarup, Lasse Bjerg, Christian S. Hansen, Daniel R. Witte, Henrik H. Thomsen, Jesper Fleischer, Rodica Pop‐Busui, Signe T. Andersen   +7 more
wiley   +1 more source

Comparing outcomes after pulmonary vein isolation in patients with systolic and diastolic heart failure

Heart Rhythm O2
Background: The benefit of pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF) is well established; its efficacy in patients with heart failure preserved ejection fraction ...
Ahmad B. Allaw, MD, Jeremy Treger, MD, PhD, Jia Guo, MD, Dipayon Roy, MD, Amulya Gampa, MD, Swati Rao, MD, Stephanie A. Besser, MSAS, Andrew D. Beaser, MD, Zaid Aziz, MD, Cevher Ozcan, MD, Srinath Yeshwant, MD, Gaurav A. Upadhyay, MD   +11 more
doaj   +1 more source