Results 131 to 140 of about 20,461 (225)

Clinical Utility of HeartInsight Score Variability in the Management of Patients With Heart Failure

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
HeartInsight threshold elevation alone may be insufficient to predict heart failure hospitalization. Monitoring daily variability in HeartInsight score may improve prediction of heart failure exacerbation, even in patients without threshold elevation or alert activation.
Takahiro Sekido, Hiroyasu Uzui, Natsuki Murata, Miku Takakura, Yuya Matunaka, Kazushi Hashiwaki, Shingo Horita, Mayumi Yoshikawa, Ryohei Nomura, Toshihiko Tsuji, Moe Mukai, Machiko Miyoshi, Kanae Hasegawa, Naoto Tama, Kentaro Ishida, Hiroshi Tada   +15 more
wiley   +1 more source

Risk Factors for Cardiovascular Disease: Epidemiology, Screening, Prevention, and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
Cardiovascular disease arises from lifelong accumulation of traditional and emerging risk factors that converge on shared pathophysiological pathways, leading to diverse clinical outcomes, and can be mitigated through integrated screening, prevention, and precision therapies. ABSTRACT Cardiovascular diseases (CVDs) remain the leading cause of morbidity
Mowei Kong, Zaiyong Zheng, Min Huang, Shengyu Huang, Xingwei Zhao, Yang Yu, Chunxiang Zhang   +6 more
wiley   +1 more source

Differential metabolomic prediction of outcomes in HFpEF and HFrEF: a prospective international multi-ethnic cohort study. [PDF]

Cardiovasc Res
Wu LH, Pakkiri LS, Tromp J, Lim PL, Liu X, Chan SP, Yang J, Samant R, Dong J, Goh E, Lee J, Ling LH, Gamble GD, Sim D, Gerard Leong KT, Yeo PSD, Ong HY, Jaufeerally F, Ng TP, Lund M, Devlin G, Troughton R, Cameron V, Lam CSP, Doughty R, Richards AM, Drum CL.   +26 more
europepmc   +1 more source

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong, Zhen Wang, Xiaoxiao Lin, Ziwen Lei, Qianqian Huang, Hang Liu, Fei Luan, Junbo Zou, Yajun Shi   +8 more
wiley   +1 more source

The Effects of Combined Antihypertensive and Antidiabetic Therapies on Cardiovascular Outcomes: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6874-6887, August 2026.
ABSTRACT Aims Hypertension and diabetes frequently coexist, yet the net clinical impact of intentionally combining antihypertensive (AHTN) and antidiabetic (ADA) therapies on cardiovascular (CV) outcomes is uncertain. Here we quantified the effects of AHTN and ADA co‐therapy on CV and blood pressure (BP)/heart rate (HR) outcomes.
Wan Chin Hsieh, Brandon Michael Henry, István Édes   +2 more
wiley   +1 more source

Cost-Effectiveness of Sodium-Glucose Co-Transporter-2 Inhibitors and Angiotensin Receptor-Neprilysin Inhibitors by Ejection Fraction and Drug Pricing in the United States: A Systematic Review. [PDF]

Circ Popul Health Outcomes
Alfie TJ, Wasfy JH, Kazi DS, Januzzi JL, Bellows BK, Cohen LP.   +5 more
europepmc   +1 more source

Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review

European Journal of Clinical Investigation, Volume 56, Issue 8, August 2026.
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino, Marco Giuseppe Del Buono, Michele Marchetta, Nicola Potere, Aldo Bonaventura, Alessandra Vecchiè, Danilo Malandrino, Giacomo Emmi, Jordana Kron, Antonio Abbate   +9 more
wiley   +1 more source

Heart failure in the elderly: epidemiology, mechanisms, and management. [PDF]

Eur Heart J
de Boer RA, Abdellatif M, Bauersachs J, Roger VL.   +3 more
europepmc   +1 more source

Real‐World Treatment of Patients With Sinus Node Dysfunction and Heart Failure With Preserved Ejection Fraction

Pacing and Clinical Electrophysiology, Volume 49, Issue 8, Page 1015-1022, August 2026.
ABSTRACT Background Permanent pacemaker (PPM) implantation is recommended in patients with sinus node dysfunction (SND). In patients with coexisting heart failure with preserved ejection fraction (HFpEF), clinicians may be hesitant to treat SND due to concerns about exacerbating heart failure.
Nicole Habel, Sarah Rosemas, Lucas Higuera, Patrick Zimmerman, Markus Meyer   +4 more
wiley   +1 more source

Glucagon-like peptide-1 receptor agonists for heart failure with reduced ejection fraction: Is it the next step? [PDF]

ESC Heart Fail
Biegus J.
europepmc   +1 more source