Insights from electromechanical simulations to assess omecamtiv mecarbil efficacy in heart failure
Abstract figure legend Impact of Omecamtiv Mecarbil (OM) on in‐silico models of heart failure. A mathematical electromechanical model of human ventricular tissue is used to simulate the effects of OM in heart failure with reduced ejection fraction (HFrEF).
Maria Teresa Mora +8 more
wiley +1 more source
Barry Greenberg, Lori B. Daniels
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Outcomes of Left Bundle Branch Area Pacing in Heart Failure Patients: A Systematic Review
LBBAP demonstrated significant improvements in cardiac function, with most studies reporting substantial increases in LVEF and reductions in QRSd. LBBAP is a promising alternative to conventional pacing strategies, offering superior electrical and mechanical synchronization, enhanced cardiac function, and better clinical outcomes.
Hina Ahmed Siddiqui +17 more
wiley +1 more source
Skeletal Muscle Mass Modifies the Prognostic Impact of LDL Cholesterol in Chronic Heart Failure
ABSTRACT Background Dyslipidaemia is among the major risk factors for atherosclerotic cardiovascular disease. Paradoxically, higher cholesterol levels are associated with better survival in heart failure (HF) of any aetiology. Because cholesterol is an integral component of skeletal muscle structure, one possible explanation involves the interplay ...
Ryosuke Sato +6 more
wiley +1 more source
APCU 29 Exploring the effects of sodium-glucose cotransporter 2 inhibitor (SGLT2 inhibitor) in elderly patients with heart failure with reduced ejection fraction (HFrEF), with and without type 2 diabetes mellitus (T2DM) [PDF]
I Hazwani +2 more
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Supraventricular Tachycardia Ablation in the Elderly—Characteristics and Outcomes
This single‐center retrospective study found that supraventricular tachycardia (SVT) ablation is safe and effective in younger and elderly patients. It should be considered for all symptomatic individuals regardless of age. However, the type of SVT and the presence of comorbidities, including frailty, should be considered in the clinical decision ...
Yi Yi Chua +8 more
wiley +1 more source
Summary The present Part 2 of the updated German S3 guideline on the treatment of psoriasis vulgaris provides recommendations for therapy selection in special clinical situations and in the presence of comorbidities. A major focus of this update is the chapter on screening for tuberculosis as well as therapy selection and management in latent ...
Alexander Nast +25 more
wiley +1 more source
Zusammenfassung Der vorliegende Teil 2 der aktualisierten S3‐Leitlinie zur Therapie der Psoriasis vulgaris bietet Empfehlungen zur Therapieauswahl in besonderen klinischen Situationen sowie bei Vorliegen von Komorbidität. Ein Schwerpunkt des Updates liegt im Kapitel Screening auf Tuberkulose sowie in der Therapieauswahl und im Management bei latenter ...
Alexander Nast +25 more
wiley +1 more source
Benefits of renal denervation in HFrEF [PDF]
openaire +2 more sources
Safety and efficacy of renal denervation in patients with heart failure with reduced ejection fraction (HFrEF): A systematic review and meta-analysis [PDF]
Zhiqiu Xia +8 more
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