Results 21 to 30 of about 19,142 (214)

Pediatric Heart Failure Pharmacotherapy: Transformative Insights for the Future

Reviews in Cardiovascular Medicine
This review aims to summarize the status and future directions of pediatric heart failure (HF) pharmacotherapy. Notably, managing HF in children presents unique challenges due to heterogeneous etiologies and a longstanding paucity of pediatric-specific ...
Bibhuti B Das
doaj   +1 more source

Neutrophils pro‐inflammatory and anti‐inflammatory cytokine release in patients with heart failure and reduced ejection fraction

ESC Heart Failure, 2021
Aims Heart failure with reduced ejection fraction (HFrEF) is characterized by sub‐clinical inflammation. Changes in selected biomarkers of inflammation concomitant with the release of pro‐inflammatory and anti‐inflammatory cytokines by neutrophils have ...
Diana Chaar, Benjamin Dumont, Branka Vulesevic, Paul‐Eduard Neagoe, Agnes Rakel, Martin G. Sirois, Michel White   +6 more
doaj   +1 more source

Intravascular Lithotripsy Is Associated With Superior Clinical Outcomes Compared to Atherectomy: A Large‐Scale, Propensity‐Matched Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Charles D. Miks, Grant K. Ozaki, Chirayu R. Shukla, Vikram Sharma   +3 more
wiley   +1 more source

Advanced heart failure with reduced ejection fraction at a young age: how long can we wait?

Cardiologia Hungarica
The pharmacotherapy and device therapy for heart failure with reduced ejection fraction (HFrEF) have advanced considerably. However, there are instances where even with optimal therapy following the guidelines’ recommendations, some patients may require ...
Arnold Péter Ráduly, Zsófia Pólik, Ágnes Balogh, László Balogh, Kriszti Medvés-Váczi, Ágnes Rácz, Bertalan Kracskó, Zoltán Csanádi, Attila Borbély   +8 more
doaj   +1 more source

Comparison of procedural outcomes in patients undergoing catheter vs surgical ablation for atrial fibrillation and heart failure with reduced ejection fraction

Journal of Arrhythmia, 2021
Background There is a lack of research comparing procedural outcomes of surgical ablation (SA) and catheter ablation (CA) among patients with heart failure with reduced ejection fraction (HFrEF) and atrial fibrillation (AF).
Rajkumar Doshi, Ashish Kumar, Mariam Shariff, Devina Adalja, Krunalkumar Patel, Kirtenkumar Patel, Rupak Desai, Nageshwara Gullapalli, Saraschandra Vallabhajosyula   +8 more
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Glucose-Induced Hemodynamic and Metabolic Response of Skeletal Muscle in Heart Failure Patients with Reduced vs. Preserved Ejection Fraction—A Pilot Study

Journal of Cardiovascular Development and Disease, 2022
(1) Background: Insulin resistance (IR) is a characteristic pathophysiologic feature in heart failure (HF). We tested the hypothesis that skeletal muscle metabolism is differently impaired in patients with reduced (HFrEF) vs.
Michael Boschmann, Lars Klug, Frank Edelmann, Anja Sandek, Stephan von Haehling, Hans-Dirk Düngen, Jochen Springer, Stefan D. Anker, Wolfram Doehner, Nadja Jauert   +9 more
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Changes of calcium cycling in HFrEF and HFpEF

Mechanobiology in Medicine, 2023
Dysfunctions of calcium cycling occur in heart failure with reduced and preserved ejection fraction (HFrEF and HFpEF). HFrEF and HFpEF showed Ca2+ leakage at diastole. The compensation of Na+/Ca2+ exchanger and the decrease of T-tubule density reduces cytoplasmic Ca2+ concentration in HFrEF and impairs systolic function.
Shou, Jian, Huo, Yunlong
openaire   +2 more sources

Outpatient treatment of decompensated heart failure: A systematic review and study level meta‐analysis

ESC Heart Failure, Volume 12, Issue 2, Page 761-769, April 2025.
Abstract Patients with acutely decompensated heart failure (ADHF) are usually admitted to hospital for management. There is growing interest in delivering intravenous (IV) diuretic therapy at home, in the community or at hospital day‐care units; the safety and effectiveness of outpatient‐based management (OPM) for ADHF has not been established.
Jameela Bahar, Amna Rahman, Grace W.Y. Wong, Rajiv Sankaranarayanan, Fozia Z. Ahmed, Rebecca Taylor, Ahmet Fuat, Iain Squire, John G.F. Cleland, Gregory Y.H. Lip, James H.P. Gamble, Sundas Masudi, Prince Josiah S. Joseph, Kenneth Y.K. Wong   +13 more
wiley   +1 more source

Use of Guideline-Recommended Heart Failure Drugs in High-, Middle-, and Low-Income Countries: A Systematic Review and Meta-Analysis

Global Heart
Optimal use of guideline-directed medical therapy (GDMT) can prevent hospitalization and mortality among patients with heart failure (HF). We aimed to assess the prevalence of GDMT use for HF across geographic regions and country-income levels.
Gautam Satheesh, Rupasvi Dhurjati, Laura Alston, Fisaha Tesfay, Rashmi Pant, Ehete Bahiru, Claudia Bambs, Anubha Agarwal, Sanne A. E. Peters, Abdul Salam, Isabelle Johansson   +10 more
doaj   +1 more source

Integration of RNA-Seq and Machine Learning Identifies Hub Genes for Empagliflozin Benefitable Heart Failure with Reduced Ejection Fraction

Journal of Inflammation Research, 2023
Qiang Yang,1,* Jing Gao,2,* Tian-Yu Wang,1 Jun-Can Ding,1 Peng-Fei Hu3 1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China; 2Department of Cardiology, Sir Run Run ...
Yang Q, Gao J, Wang TY, Ding JC, Hu PF
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