Results 41 to 50 of about 32,363 (292)

What can we learn from SOCRATES: more questions than answers? [PDF]

open access: yes, 2017
This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
core   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu   +3 more
wiley   +1 more source

Advanced heart failure with reduced ejection fraction at a young age: how long can we wait?

open access: yesCardiologia Hungarica
The pharmacotherapy and device therapy for heart failure with reduced ejection fraction (HFrEF) have advanced considerably. However, there are instances where even with optimal therapy following the guidelines’ recommendations, some patients may require ...
Arnold Péter Ráduly   +8 more
doaj   +1 more source

Integration of RNA-Seq and Machine Learning Identifies Hub Genes for Empagliflozin Benefitable Heart Failure with Reduced Ejection Fraction

open access: yesJournal of Inflammation Research, 2023
Qiang Yang,1,* Jing Gao,2,* Tian-Yu Wang,1 Jun-Can Ding,1 Peng-Fei Hu3 1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China; 2Department of Cardiology, Sir Run Run ...
Yang Q, Gao J, Wang TY, Ding JC, Hu PF
doaj  

Comparison of procedural outcomes in patients undergoing catheter vs surgical ablation for atrial fibrillation and heart failure with reduced ejection fraction

open access: yesJournal of Arrhythmia, 2021
Background There is a lack of research comparing procedural outcomes of surgical ablation (SA) and catheter ablation (CA) among patients with heart failure with reduced ejection fraction (HFrEF) and atrial fibrillation (AF).
Rajkumar Doshi   +8 more
doaj   +1 more source

Changes of calcium cycling in HFrEF and HFpEF

open access: yesMechanobiology in Medicine, 2023
Dysfunctions of calcium cycling occur in heart failure with reduced and preserved ejection fraction (HFrEF and HFpEF). HFrEF and HFpEF showed Ca2+ leakage at diastole. The compensation of Na+/Ca2+ exchanger and the decrease of T-tubule density reduces cytoplasmic Ca2+ concentration in HFrEF and impairs systolic function.
Shou, Jian, Huo, Yunlong
openaire   +2 more sources

Socio‐economic inequalities and heart failure morbidity and mortality: A systematic review and data synthesis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 927-941, April 2025.
Abstract Socio‐economic status (SES) has been associated with incident and prevalent heart failure (HF), as well as its morbidity and mortality. However, the precise nature of the relationship between SES and HF remains unclear due to inconsistent data. This study aims to provide a comprehensive assessment and data synthesis of the relationship between
Abdul Shakoor   +8 more
wiley   +1 more source

Use of Guideline-Recommended Heart Failure Drugs in High-, Middle-, and Low-Income Countries: A Systematic Review and Meta-Analysis

open access: yesGlobal Heart
Optimal use of guideline-directed medical therapy (GDMT) can prevent hospitalization and mortality among patients with heart failure (HF). We aimed to assess the prevalence of GDMT use for HF across geographic regions and country-income levels.
Gautam Satheesh   +10 more
doaj   +1 more source

Clinical, Echocardiographic, and Therapeutic Characteristics of Heart Failure in Patients with Preserved, Mid-Range, and Reduced Ejection Fraction: Future Directions

open access: yesInternational Journal of General Medicine, 2021
Manal M Alem Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaCorrespondence: Manal M AlemDepartment of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal ...
Alem MM
doaj  

Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation

open access: yesFrontiers in Physiology, 2018
Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases that often co-exist. Animal models have suggested complex AF-promoting atrial structural, electrical, and Ca2+-handling remodeling in the setting of HF, but data in human ...
Cristina E. Molina   +15 more
doaj   +1 more source

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