Results 51 to 60 of about 132 (131)

Postcranial anatomy and osteohistology of an early prozostrodont cynodont from the Upper Triassic of Brazil

The Anatomical Record, EarlyView.
Abstract Prozostrodon brasiliensis, a probainognathian cynodont of the clade Prozostrodontia, is recognized as a key taxon for understanding the origin of Mammaliaformes and mammals. Despite detailed investigations of its cranial anatomy, the postcranial skeleton has received comparatively less attention.
Iasmim M. Michelotti, Lívia Roese‐Miron, Brodsky Dantas Macedo Farias, Marina Bento Soares, Leonardo Kerber   +4 more
wiley   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Age‐associated B cells contribute to inflammation via antibody‐independent mechanisms in Takayasu's arteritis

Arthritis &Rheumatology, Accepted Article.
Objective Although Takayasu's arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B‐cell activation and its contributions to TAK pathogenesis.
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source

Tensionable Knotless Tendon‐Sparing Biceps Rerouting Technique for Irreparable Rotator Cuff Tears

Arthroscopy Techniques, EarlyView.
Abstract This technique describes a tensionable knotless tendon‐sparing biceps rerouting for superior capsular reconstruction using the long head of the biceps in irreparable supraspinatus tears. The long head of the biceps is arthroscopically released from the bicipital groove, rerouted over the greater tuberosity footprint, and secured with 2 self ...
Ignancio Pérez, Pia Stefano, Hady Ezzeddine, Alex Campagnoli, Xavi Rius, Abdul‐ilah Hachem   +5 more
wiley   +1 more source

Anterior Capsular Reconstruction With Dermal Allograft Augmentation for Multidirectional Shoulder Instability

Arthroscopy Techniques, EarlyView.
Abstract Multidirectional shoulder instability, particularly in patients with underlying connective tissue disorders poses a surgical challenge. After exhaustive nonoperative treatment, surgical intervention is focused on restoration of the anterior and inferior capsular restraints.
Mikalyn T. DeFoor, Nate Dickinson, Ryan J. Froom, Ryan J. Whalen, Tomas Aguirre, Christopher Bine, Matthew T. Provencher   +6 more
wiley   +1 more source

Arthroscopic High‐in‐the‐Groove Biceps Tenodesis: Loop‐and‐Tack Technique

Arthroscopy Techniques, EarlyView.
Abstract Arthroscopic biceps tenodesis is an effective treatment for patients with long head of the biceps tendon pathology. This technical note details a high‐in‐the‐groove arthroscopic technique utilizing loop‐and‐tack fixation through a single cannula.
Marc Nicholes, Micah Ngatuvai, Nata Parnes, John P. Scanaliato   +3 more
wiley   +1 more source

Arthroscopic Remplissage With Knotless All‐Suture Anchors and Concomitant Bankart Repair: Technical Considerations

Arthroscopy Techniques, EarlyView.
Abstract Anterior shoulder instability is common in active patients. Traumatic dislocations may produce Bankart and Hill‐Sachs lesions that increase recurrence risk. In high‐demand individuals, isolated Bankart repair may be insufficient for off‐track or near‐track Hill‐Sachs lesions.
Michael Nocek, Lorenz Fritsch, Colby C. Wollenman, Ayham Jaber, Alan D. Villegas Meza, Katelyn L. Kirwood, Peter J. Millett   +6 more
wiley   +1 more source

Reinforcing Anterosuperior Medium‐to‐Large Rotator Cuff Repairs With the Long Head of the Biceps Tendon and Dermal Allograft Patch Using a Knotless Double‐Row Technique

Arthroscopy Techniques, EarlyView.
Abstract We describe a surgical technique repairing medium‐to‐large anterosuperior rotator cuff (RC) tear that combines long head of the biceps tendon (LHBT) augmentation with a dermal allograft patch using a knotless double‐row repair. LHBT augmentation is done using a triple‐loaded anchor placed 5 mm posterior to the bicipital groove at the bone ...
Gabriel Antonio A. Escueta, Joe Chih‐Hao Chiu, Al Kung‐Tseng Hung, Jijulal C. U., Abdel Kareem Adnan Khdairat, Vijay Krishnan K.   +5 more
wiley   +1 more source

Arthroscopic Noninvasive Transtendon Double‐Pulley Suture‐Bridge Repair of Both‐Sided Partial‐Thickness Rotator Cuff Tears

Arthroscopy Techniques, EarlyView.
Abstract Currently, surgical techniques for both‐sided partial‐thickness rotator cuff tears (PTRCTs) are rarely described, and the successful repair of both‐sided PTRCTs is challenging. Transtendon repair is a good technique for repairing PTRCTs, but the resulting trauma to the tendon is unacceptable.
Peiguan Huang, Hairong Tang, Xiaoxu Wang, Yong Fu, Zhengmao Li, Chunrong He   +5 more
wiley   +1 more source