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Вопросы вирусологии, 2018 Introduction. Human herpes virus type 6 (HHV 6) can cause serious infectious complications in immunodeficient patients. It is also capable of integrating into the genome of the infected cell.
N. G. Yaroslavtseva +6 more
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The Antiviral Activity of Polyphenols
Molecular Nutrition &Food Research, EarlyView.Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard +5 more
wiley +1 more source
, 2014 Multiple sclerosis (MS) is an inflammatory demyelinating disease affecting the central nervous system, thought to be an autoimmune disease mediated by autoreactive lymphocytes. The pathogenesis of MS is multifactorial and is thought to be triggered by multiple environmental factors in genetically susceptible individuals.
Jeanne Billioux, Bridgette +2 more
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Infection with HHV-6 and its role in epilepsy
Epilepsy Research, 2019 Infection with Human Herpesvirus-6 (HHV-6) has been associated with different epilepsy syndromes, including febrile seizures and status epilepticus, acute symptomatic seizures secondary to encephalitis and temporal lobe epilepsy. This neurotropic DNA virus is ubiquitous and primary infection occurs in up to 80% of children by age two years.
Bartolini L +3 more
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Antibody status to HHV-6 in children with leukaemia [PDF]
Leukemia, 2002 Forty children with acute lymphoblastic (33) or myeloid leukaemia (seven) were studied for IgG and IgM antibodies and IgG avidity against human herpesvirus 6 (HHV-6) at the time of diagnosis, and compared with age-, sex- and season-matched children with various neurological diseases of suspected viral origin.
Marjaleena Koskiniemi +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Clostridioides difficile infection (CDI) represents a significant health risk to pediatric stem cell transplant (SCT) patients. In these patients, recurrent CDI is common, requiring prolonged antibiotic usage and increased hospitalization. Bezlotoxumab, a monoclonal antibody that targets the toxin responsible for CDI, has demonstrated efficacy
Aaron E. Fan +8 more
wiley +1 more source
GP96 interacts with HHV-6 during viral entry and directs it for cellular degradation.
PLoS ONE, 2014 CD46 and CD134 mediate attachment of Human Herpesvirus 6A (HHV-6A) and HHV-6B to host cell, respectively. But many cell types interfere with viral infection through rapid degradation of viral DNA.
Bhupesh K Prusty +4 more
doaj +1 more source
Human Herpesvirus 6 (HHV-6) Causes Severe Thymocyte Depletion in SCID-hu Thy/Liv Mice [PDF]
, 1999 Human herpesvirus 6 (HHV-6) is a potentially immunosuppressive agent that may act as a cofactor in the progression of AIDS. Here, we describe the first small animal model of HHV-6 infection.
Alberto Gobbi +45 more
core +5 more sources
Small Methods, EarlyView.This work presents a single‐molecule detection platform that does not rely on the partitioning of analyzed liquid samples and on enzymatic amplification of fluorescence signals. A flexible polymer linker serves to spatially confine catalytic‐harpin assembly‐based DNA amplification.
Naoto Asai +6 more
wiley +1 more source
Association of HHV-6 with Hodgkin and non Hodgkin lymphoma
Iranian Journal of Microbiology, 2016 Background and Objectives: Human Herpes 6 virus (HHV-6) could remain latent and chronic in the host cells after primary infection. HHV-6 genome encodes certain trans activation proteins which may results in development of malignantlymphoma.
Hadis Kiani +11 more
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