Results 101 to 110 of about 8,215,521 (293)

Modulatory effects on dendritic cells by human herpesvirus 6 [PDF]

open access: yes, 2015
Human herpesvirus 6A and 6B are β-herpesviruses approaching 100% seroprevalance worldwide. These viruses are involved in several clinical syndromes and have important immunomodulatory effects.
Anna Fogdell-Hahn   +2 more
core   +2 more sources

Power‐to‐X Processes with Synthetic Iron Oxides

open access: yessteel research international, EarlyView.
Iron oxide redox cycling connects electrolytic hydrogen production and storage, enabling synthesis gas generation for synthetic hydrocarbons. Integrating H2/CO2 cycles offers carbon‐neutral energy storage and industrial applications, especially in commodity chemical industries. An aluminous‐rich binder stabilizes a sample over 20 H2/CO2 cycles, without
Julien Göthel   +3 more
wiley   +1 more source

A case of DRESS syndrome due to Vancomycin [PDF]

open access: yes, 2013
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe systemic reaction that usually begins 2-6 weeks after the introduction of the inciting agent.
Steinmann, William, Zimmerman, Danielle
core  

Lamotrigine and anti‐seizure medications in HLH: A systematic review

open access: yesBritish Journal of Haematology, EarlyView.
Lamotrigine and other anti‐seizure medications have been reported to cause both haemophagocytic lympho‐histiocytosis (HLH) and drug‐induced hypersensitivity syndrome (DIHS). HLH and DIHS have many characteristic clinical, laboratory, pathological findings and underlying mechanisms; we identified significant clinical overlap between these two syndromes ...
Yaswanta K. Gummadi   +4 more
wiley   +1 more source

Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome [PDF]

open access: yes, 2013
Linear chromosomes are stabilized by telomeres, but the presence of short dysfunctional telomeres triggers cellular senescence in human somatic tissues, thus contributing to ageing.
Clark, D.A.   +13 more
core   +2 more sources

T cells from newly diagnosed multiple sclerosis patients have enhanced responsiveness to CD46 activation

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods T cells from MS patients and non‐diseased symptomatic controls (SC) were activated in vitro with or without αCD46 antibody co‐stimulation.
Linda Sundvall   +6 more
wiley   +1 more source

Peripheral blood biomarkers in multiple sclerosis. [PDF]

open access: yes, 2015
Multiple sclerosis is the most common autoimmune disorder affecting the central nervous system. The heteroge-neity of pathophysiological processes in MS contributes to the highly variable course of the disease and unpre-dictable response to therapies ...
Acheson   +298 more
core   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

open access: yesCell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far   +4 more
wiley   +1 more source

A new piece in the repeatome puzzle of Triatominae bugs: The analysis of Triatoma rubrofasciata reveals the role of satellite DNAs in the karyotypic evolution of distinct lineages

open access: yesInsect Molecular Biology, EarlyView.
Satellite DNAs comprise the major component of the Triatoma rubrofasciata repeatome, highlighting their central role in genome composition and architecture. Satellite DNA families show recent amplification in heterochromatin and older, more divergent satellite DNAs located in euchromatin, indicating distinct evolutionary histories.
Sebastián Pita   +8 more
wiley   +1 more source

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