Results 101 to 110 of about 8,385,421 (296)

Effectiveness and safety of tocilizumab combined with different high‐dose methylprednisolone regimens for acute necrotizing encephalopathy in children

Pediatric Investigation, EarlyView.
Tocilizumab combined with high‐dose methylprednisolone improved outcomes in children with acute necrotizing encephalopathy. A dose of 30 mg/(kg·day) may be more effective than 20 mg/(kg·day). ABSTRACT Importance Acute necrotizing encephalopathy (ANE) is a rare but life‐threatening pediatric neurological disorder characterized by rapid progression and ...
Fei Li, Kechun Li, Chaonan Fan, Quan Wang, Suyun Qian   +4 more
wiley   +1 more source

Herpesvirus-Associated Acute Urticaria: An Age Matched Case-Control Study [PDF]

, 2013
Background Acute and recurrent acute urticaria are often associated with multiple factors including infections and recent data suggest a role for herpesviruses.
A Arena, A Kumar, AJ Kanwar, Arianna Mareri, AW McMahon, B Wedi, C Nilsson, C Sackesen, C Smith, C-C Wu, D Lipsker, DE Schuller, DH Dreyfus, DV Ablashi, Giovanni Nigro, JA Levy, James P. Stewart, JC Caubet, JD Cherry, JL Dienstag, JM Corne, Kanokvalai, LJ Scully, M Hide, OL Frick, P Mortureux, SM McAlpine, Stuart P. Adler, T Zuberbier, T Zuberbier, YR Liu   +30 more
core   +3 more sources

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

Epilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu, Jules Jeuris, Wim Van Paesschen   +2 more
wiley   +1 more source

Human Herpesvirus-6 Pneumonitis around the Engraftment of Cord Blood Transplantation following Foscarnet Prophylaxis in a Patient with Acute Leukemia

Case Reports in Hematology, 2015
Human herpesvirus-6 (HHV-6) reactivation is sometimes observed in immunocompromised patients, especially after allogeneic stem cell transplantation. The complications of HHV-6 reactivation in this setting are mainly recognized as HHV-6 encephalitis.
Takashi Ishio, Tomoyuki Endo, Kohei Okada, Akio Shigematsu, Satoshi Hashino, Takanori Teshima   +5 more
doaj   +1 more source

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

The FEBS Journal, EarlyView.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu, Noemi Nagy, Carlos Mario Ayala‐Torres, Maria G. Masucci   +3 more
wiley   +1 more source

Characterization of human herpesvirus 6A/B U94 as ATPase, helicase, exonuclease and DNA-binding proteins [PDF]

, 2015
Human herpesvirus-6A (HHV-6A) and HHV-6B integrate their genomes into the telomeres of human chromosomes, however, the mechanisms leading to integration remain unknown. HHV-6A/B encode a protein that has been proposed to be involved in integration termed
Collin, Vanessa, Dubuc, Isabelle, Flamand, Louis, Gilbert-Girard, Shella, Gravel, Annie, Kaufer, Benedikt B., Morissette, Guillaume, Trempe, Frédéric, Wallaschek, Nina   +8 more
core   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

In vitro evaluation of antiviral and virucidal activity of a high molecular weight hyaluronic acid. [PDF]

, 2011
BACKGROUND: hyaluronic acid (HA), a non-sulphated glycosaminoglycan, is present in synovial fluid, vitreous humour serum and many connective tissues. Pharmaceutical preparations of HA are used in clinical practice for wound healing, joint pain, kerato ...
ARDIZZONI, Andrea, Bettua C, BLASI, Elisabetta, CERMELLI, Claudio, Cuoghi A, Iannitti T, NEGLIA, Rachele Giovanna, PALMIERI, Beniamino, Scuri M   +8 more
core   +2 more sources

Scoping Review of Sexual and Gender Minority Health Research in Ireland

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To map existing sexual and gender minority (SGM) health research in Ireland, identify gaps in literature and outline priorities for future research and healthcare. SGM is an umbrella term that includes people who identify as lesbian, gay, bisexual, transgender, queer or intersex and is sometimes abbreviated as LGBTQI+.
John P. Gilmore, Tonda L. Hughes, Sean Kearns, Laurie A. Drabble, Diarmuid Stokes, Siobhán D. Thomas, Chris Noone, Lauren Bochicchio   +7 more
wiley   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source