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Blood, 2011
Human herpesvirus 6 (HHV-6) is recognized as a sporadic cause of encephalitis in hematopoietic cell transplantation (HCT) recipients. In this issue of Blood, Zerr and coworkers report on a 3.5-year prospective study of 315 patients undergoing allogeneic HCT. 1 Patients with HHV-6 were more likely to develop delirium and neurocognitive decline.
Mary T, Caserta, Stephen, Dewhurst
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Human herpesvirus 6 (HHV-6) is recognized as a sporadic cause of encephalitis in hematopoietic cell transplantation (HCT) recipients. In this issue of Blood, Zerr and coworkers report on a 3.5-year prospective study of 315 patients undergoing allogeneic HCT. 1 Patients with HHV-6 were more likely to develop delirium and neurocognitive decline.
Mary T, Caserta, Stephen, Dewhurst
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HHV-6 antigen and HHV-6 DNA expression in sporadic adenomatous polyps of the colon
Scandinavian Journal of Gastroenterology, 2013BACKGROUND. Human herpesvirus-6B (HHV-6B) antigens are commonly found in the intestinal mucosa of patients with immunosuppression. In a series of immunocompetent patients with adenomatous, polyp HHV-6B antigen expression from mucosal biopsies was more intense than in biopsies taken from patients receiving immunosuppressive drugs because of kidney ...
Lautenschlager Irmeli +9 more
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Annali di igiene : medicina preventiva e di comunita, 2004
HHV-6 is the etiological agent of Exanthema subitum, and its role in human infection is well known. Recently, molecular diagnostics tools showed for HHV-6 new pathogenetic features and new clinical implication. The present paper highlights recent knowledge on HHV-6 infection and presents a number of results concerning HHV-6 infection in children who ...
COMAR, Manola +6 more
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HHV-6 is the etiological agent of Exanthema subitum, and its role in human infection is well known. Recently, molecular diagnostics tools showed for HHV-6 new pathogenetic features and new clinical implication. The present paper highlights recent knowledge on HHV-6 infection and presents a number of results concerning HHV-6 infection in children who ...
COMAR, Manola +6 more
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Trends in Microbiology, 1998
The paper by Soldan et al. provides further evidence of a link between human herpesvirus 6 (HHV-6) and multiple sclerosis (MS). Serum from patients with relapsing and remitting MS had a greater incidence of immunoglobulin M (IgM) to an HHV-6 early viral antigen, p41/38, than normal serum or serum from patients with other neurological or inflammatory ...
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The paper by Soldan et al. provides further evidence of a link between human herpesvirus 6 (HHV-6) and multiple sclerosis (MS). Serum from patients with relapsing and remitting MS had a greater incidence of immunoglobulin M (IgM) to an HHV-6 early viral antigen, p41/38, than normal serum or serum from patients with other neurological or inflammatory ...
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Nihon rinsho. Japanese journal of clinical medicine, 2011
Primary human herpesvirus 6(HHV-6) and HHV-7 infections cause exanthem subitum. The disease is common febrile illness in infants, indeed these viruses rarely cause encephalopathy. Recently, various types of encephalopathy have been reported in the patient with HHV-6. Therefore, appropriate treatment should be developed for each type of the encephalitis.
Yoshiki, Kawamura, Tetsushi, Yoshikawa
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Primary human herpesvirus 6(HHV-6) and HHV-7 infections cause exanthem subitum. The disease is common febrile illness in infants, indeed these viruses rarely cause encephalopathy. Recently, various types of encephalopathy have been reported in the patient with HHV-6. Therefore, appropriate treatment should be developed for each type of the encephalitis.
Yoshiki, Kawamura, Tetsushi, Yoshikawa
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Herpes : the journal of the IHMF, 2006
Human herpes virus-6 (HHV-6) is a ubiquitous virus, but one that can induce various neurological diseases. Recently, several seizures have been reported as new HHV-6-associated diseases based on virological analysis. Neonates who are perinatally infected with HHV-6 can develop afebrile seizures, which are considered to be exanthem subitum (ES) in the ...
Nobuko, Yamashita, Tsuneo, Morishima
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Human herpes virus-6 (HHV-6) is a ubiquitous virus, but one that can induce various neurological diseases. Recently, several seizures have been reported as new HHV-6-associated diseases based on virological analysis. Neonates who are perinatally infected with HHV-6 can develop afebrile seizures, which are considered to be exanthem subitum (ES) in the ...
Nobuko, Yamashita, Tsuneo, Morishima
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2006
Publisher Summary This chapter discusses the body of knowledge accrued over the last two decades on the biology of human herpesvirus-6 (HHV-6). HHV-6 has a restricted range of susceptible species, essentially limited to humans and selected nonhuman primates.
Lorenzo Dagna +2 more
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Publisher Summary This chapter discusses the body of knowledge accrued over the last two decades on the biology of human herpesvirus-6 (HHV-6). HHV-6 has a restricted range of susceptible species, essentially limited to humans and selected nonhuman primates.
Lorenzo Dagna +2 more
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HHV-6 inhibition by two polar compounds
Antiviral Research, 1992Dimethyl sulphoxide and dimethyl formamide, two polar compounds and powerful cell differentiation inducers, inhibit HHV-6 infection when added to HHV-6-infected HSB2 cultures. This was established by a delay in the time-course of infection and in the development of virus-induced cytopathic effects.
D, Viza +3 more
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Hemophagocytic Syndrome Revealing Primary HHV-6 Infection
The Journal of Pediatrics, 2010Figure. Bone marrow smears during hemophagocytic syndrome concurrent to HHV-6 primary infection. A, Hemophagocytosis of 7 red blood cells into a single macrophage. B, Activated macrophages and lymphocytes destroying red blood cells (lymphohistiocytosis). O n day 7 after a course of vincristin-actinomycin for bilateral nephroblastomatosis, a 14-monthold
Aurélien, Marabelle +4 more
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2006
Publisher Summary Human herpesvirus-6 (HHV-6) is classified into variants A (HHV-6A) and B (HHV-6B) on the basis of distinct genetic, immunological, and biological characteristics. The HHV-6 genome contains open reading frames (ORFs) U1-U100 and flanking 8–9 kb terminal direct repeats (DRs) at either end.
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Publisher Summary Human herpesvirus-6 (HHV-6) is classified into variants A (HHV-6A) and B (HHV-6B) on the basis of distinct genetic, immunological, and biological characteristics. The HHV-6 genome contains open reading frames (ORFs) U1-U100 and flanking 8–9 kb terminal direct repeats (DRs) at either end.
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