Epidemiology and Genetic Variability of HHV-8/KSHV among Rural Populations and Kaposi's Sarcoma Patients in Gabon, Central Africa. Review of the Geographical Distribution of HHV-8 K1 Genotypes in Africa. [PDF]
Viruses, 2021 Human herpesvirus 8 (HHV-8) is the etiological agent of all forms of Kaposi’s sarcoma (KS). K1 gene studies have identified five major molecular genotypes with geographical clustering.
Mamimandjiami AI +8 more
europepmc +3 more sources
HHV-8-Associated Lymphoproliferative Disorders and Pathogenesis in an HIV-Positive Patient. [PDF]
Case Rep Hematol, 2019 Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus, is a DNA oncovirus known for its role in the development of Kaposi’s sarcoma (KS) and several lymphoproliferative disorders (LPDs). HHV-8 promotes lymphoproliferation via
Guerrero C, Jain T, Kelemen K.
europepmc +3 more sources
Non-detection of human herpesvirus 8 (HHV-8) DNA in HHV-8-seropositive blood donors from three Brazilian regions. [PDF]
PLoS ONE, 2011 Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is the etiologic agent of all forms of Kaposi's sarcoma, primary effusion lymphoma and the plasmablastic cell variant of multicentric Castleman disease. In endemic
José Eduardo Levi +6 more
doaj +4 more sources
Angiosarcoma in HIV-negative patients is not associated with HHV-8. [PDF]
An Bras Dermatol, 2016 : BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as ...
Avancini J +8 more
europepmc +8 more sources
HHV-8 seroprevalence: a global view [PDF]
Systematic Reviews, 2014 Human herpes virus 8 (HHV-8) is the underlying infectious cause of Kaposi sarcoma (KS) and other proliferative diseases; that is, primary effusion lymphoma and multicentric Castleman disease. In regions with high HHV-8 seroprevalence in the general population, KS accounts for a major burden of disease. Outside these endemic regions, HHV-8 prevalence is
Eliane Rohner +8 more
openaire +6 more sources
Are Patients with HHV-8 Associated Castleman Disease Successfully Treated with Rituximab at Risk of Subsequently Developing HHV-8 Negative (Idiopathic) Castleman Disease? [PDF]
Eur J Case Rep Intern Med, 2023 Introduction: Multicentric Castleman disease (MCD) is a lymphoproliferative disorder characterized by lymph node histopathology and systemic symptoms.
Ha G +4 more
europepmc +2 more sources
Update on HHV-8-Associated Malignancies [PDF]
Current Infectious Disease Reports, 2010 The human herpesvirus 8 (HHV-8) is the oncogenic virus associated with Kaposi's sarcoma (KS) and lymphoproliferative disorders, namely, primary effusion lymphoma and multicentric Castleman's disease. KS is among the most common malignancies seen in HIV-infected patients despite the decreased incidence of KS in the era of highly active antiretroviral ...
Sunil, Meena +2 more
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HHV-8 Seroprevalence and Genotype Distribution in Africa, 1998⁻2017: A Systematic Review. [PDF]
Viruses, 2018 Human herpes virus type 8 (HHV-8) is the causative agent of Kaposi’s sarcoma (KS). We systematically reviewed literature published between 1998 and 2017, according to the PRISMA guidelines, to understand the distribution of HHV-8 infection in Africa ...
Etta EM +4 more
europepmc +2 more sources
HHV-8 infection in patients with AIDS-related Kaposi's sarcoma in Brazil [PDF]
Brazilian Journal of Medical and Biological Research, 2001 The aims of the present study were to determine the prevalence of human herpesvirus type 8 (HHV-8) in HIV-positive Brazilian patients with (HIV+/KS+) and without Kaposi's sarcoma (HIV+/KS-) using PCR and immunofluorescence assays, to assess its ...
Keller R. +8 more
doaj +2 more sources
São Paulo Medical Journal, 2015 CONTEXT AND OBJECTIVE: Kaposi's sarcoma (KS) is a common neoplastic disease in AIDS patients. The aim of this study was to evaluate the frequency of human herpesvirus 8 (HHV-8) infection in human immunodeficiency virus (HIV)-infected patients, with or ...
Paula Renata Lima Machado +4 more
doaj +2 more sources