Epidemiology and Genetic Variability of HHV-8/KSHV among Rural Populations and Kaposi’s Sarcoma Patients in Gabon, Central Africa. Review of the Geographical Distribution of HHV-8 K1 Genotypes in Africa [PDF]
Viruses, 2021 Human herpesvirus 8 (HHV-8) is the etiological agent of all forms of Kaposi’s sarcoma (KS). K1 gene studies have identified five major molecular genotypes with geographical clustering.
Antony Idam Mamimandjiami +8 more
doaj +3 more sources
HHV-8-Associated Lymphoproliferative Disorders and Pathogenesis in an HIV-Positive Patient [PDF]
Case Reports in Hematology, 2019 Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus, is a DNA oncovirus known for its role in the development of Kaposi’s sarcoma (KS) and several lymphoproliferative disorders (LPDs). HHV-8 promotes lymphoproliferation via
Carlo Guerrero +2 more
doaj +3 more sources
Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]
, 2003 Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
R. C. Paul +9 more
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Durable remission of both multicentric Castleman's disease and Kaposi's sarcoma with valganciclovir, rituximab and liposomal doxorubicin in an HHV-8-positive, HIV-negative patient [PDF]
Journal of Clinical Pharmacy and Therapeutics, 2016 Human herpesvirus‐8 (HHV‐8)‐positive, HIV‐negative multicentric Castleman's disease is a rare lymphoproliferative disorder with no standardized treatment.
Cheryl Murphy +3 more
openalex +2 more sources
Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis [PDF]
Frontiers in Microbiology, 2014 Human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Diana M. Campbell +5 more
doaj +3 more sources
Are patients with HHV-8 associated Castleman disease successfully treated with rituximab at risk of subsequently developing HHV-8 negative (idiopathic) Castleman disease? [PDF]
European Journal of Case Reports in Internal Medicine, 2023 Introduction: Multicentric Castleman disease (MCD) is a lymphoproliferative disorder characterized by lymph node histopathology and systemic symptoms.
Gavin Ha +4 more
doaj +2 more sources
Non-detection of human herpesvirus 8 (HHV-8) DNA in HHV-8-seropositive blood donors from three Brazilian regions. [PDF]
PLoS ONE, 2011 Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is the etiologic agent of all forms of Kaposi's sarcoma, primary effusion lymphoma and the plasmablastic cell variant of multicentric Castleman disease. In endemic
José Eduardo Levi +6 more
doaj +2 more sources
HHV-8 Seroprevalence and Genotype Distribution in Africa, 1998⁻2017: A Systematic Review. [PDF]
Viruses, 2018 Human herpes virus type 8 (HHV-8) is the causative agent of Kaposi’s sarcoma (KS). We systematically reviewed literature published between 1998 and 2017, according to the PRISMA guidelines, to understand the distribution of HHV-8 infection in Africa ...
Etta EM +4 more
europepmc +2 more sources
São Paulo Medical Journal, 2015 CONTEXT AND OBJECTIVE: Kaposi's sarcoma (KS) is a common neoplastic disease in AIDS patients. The aim of this study was to evaluate the frequency of human herpesvirus 8 (HHV-8) infection in human immunodeficiency virus (HIV)-infected patients, with or ...
Paula Renata Lima Machado +4 more
doaj +2 more sources
International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease [PDF]
Blood, 2017 David C. Fajgenbaum +37 more
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