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HHV-8, transfusion, and mortality. [PDF]
Journal of Infectious Diseases, 2012 E. Operskalski
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Current Opinion in Oncology, 2022
Purpose of review The discovery of Kaposi sarcoma herpesvirus (KSHV) / human herpesvirus 8 (HHV-8) led to recognition of primary effusion lymphoma (PEL) as a distinct lymphoproliferative disorder. Subsequently, two other types of lymphoma have been shown to be associated with HHV-8 : HHV-8 positive diffuse large B cell lymphoma
Eric, Oksenhendler, Véronique, Meignin
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Purpose of review The discovery of Kaposi sarcoma herpesvirus (KSHV) / human herpesvirus 8 (HHV-8) led to recognition of primary effusion lymphoma (PEL) as a distinct lymphoproliferative disorder. Subsequently, two other types of lymphoma have been shown to be associated with HHV-8 : HHV-8 positive diffuse large B cell lymphoma
Eric, Oksenhendler, Véronique, Meignin
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The role of HHV-8 in Kaposi's sarcoma
Seminars in Cancer Biology, 1999The epidemiology of Kaposi's sarcoma (KS) amongst North American and Northern European patients with AIDS suggests that an infectious agent other than HIV is involved in its pathogenesis. Several lines of evidence indicate that human herpesvirus 8 (HHV-8), also termed Kaposi's sarcoma associated herpesvirus, is the sought after agent.
Bernhard Fleckenstein +2 more
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Blood, 2000
Castleman disease (CD) is a lymphoproliferative disorder of unknown etiology that is associated with the development of secondary tumors, including B-cell lymphoma. Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma–associated herpesvirus) sequences have been described in some cases of multicentric Castleman disease (MCD).
N. Dupin +8 more
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Castleman disease (CD) is a lymphoproliferative disorder of unknown etiology that is associated with the development of secondary tumors, including B-cell lymphoma. Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma–associated herpesvirus) sequences have been described in some cases of multicentric Castleman disease (MCD).
N. Dupin +8 more
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HHV-8 and multiple myeloma in the UK
The Lancet, 1997Rettig and colleagues reported an association between HHV-8 and multiple myeloma. HHV-8 genomic sequences were detected by PCR in cultured bone-marrow stromal cells from 15 of 15 patients with multiple myeloma and from two of eight patients with monoclonal gammopathy of uncertain significance, but not from 26 controls.
J, MacKenzie +5 more
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New England Journal of Medicine, 1999
To the Editor: We reported previously on mother-to-child transmission of human herpesvirus 8 (HHV-8) in South Africa.1 Stored serum samples obtained from 107 women (60 were black, 24 white, 5 Asian, and 18 other) and 112 of their children between the ages of 6 months and 14 years (61 girls, 50 boys, and 1 unknown) were tested for HHV-8: 42 percent (8 ...
F, Sitas, R, Newton, C, Boshoff
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To the Editor: We reported previously on mother-to-child transmission of human herpesvirus 8 (HHV-8) in South Africa.1 Stored serum samples obtained from 107 women (60 were black, 24 white, 5 Asian, and 18 other) and 112 of their children between the ages of 6 months and 14 years (61 girls, 50 boys, and 1 unknown) were tested for HHV-8: 42 percent (8 ...
F, Sitas, R, Newton, C, Boshoff
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Transfusion, 2009
BACKGROUND: Human herpesvirus 8 (HHV‐8) is endemic in Uganda where seroprevalence is approximately 40%. In a previous study, Ugandan patients receiving blood transfusions had multiple serum specimens collected for 6 months after transfusion to monitor for HHV‐8 infection.
Ashley L, Fowlkes +8 more
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BACKGROUND: Human herpesvirus 8 (HHV‐8) is endemic in Uganda where seroprevalence is approximately 40%. In a previous study, Ugandan patients receiving blood transfusions had multiple serum specimens collected for 6 months after transfusion to monitor for HHV‐8 infection.
Ashley L, Fowlkes +8 more
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Absence of HHV‐8 DNA in hobnail hemangiomas
Journal of Cutaneous Pathology, 2002Background: Hobnail hemangioma (HH) is a rare subtype of hemangioma that shares the morphological feature of hobnail endothelia with retiform hemangioendothelioma (RHE) and has to be considered in the differential diagnosis of Kaposi sarcoma. Since DNA of the human herpesvirus type 8 (HHV‐8) has been detected in more than 90% of Karposi sarcomas and ...
Ralf, Gutzmer +4 more
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HHV‐8 and AIDS‐related CNS lymphoma
Neurology, 1997Human herpesvirus 8 (HHV-8), the Kaposi's sarcoma (KS)-associated herpesvirus, is closely related to the transforming Epstein-Barr virus (EBV) and may be detected in AIDS-related, EBV-containing, body-cavity-based lymphomas. Accordingly, we analyzed 27 EBV-positive, AIDS-related CNS lymphomas for HHV-8 sequences. Only one tumor yielded HHV-8 sequences;
S, Morgello, M, Tagliati, M R, Ewart
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Blood, 2011
With increasing life expectancy for HIV-infected persons, the ravages of both AIDS-defining and non-AIDS cancers become increasingly prominent. In this issue of Blood , Stebbing et al present work that will aid not only in the diagnosis of MCD, but could lead to preventative therapy.[1][1]
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With increasing life expectancy for HIV-infected persons, the ravages of both AIDS-defining and non-AIDS cancers become increasingly prominent. In this issue of Blood , Stebbing et al present work that will aid not only in the diagnosis of MCD, but could lead to preventative therapy.[1][1]
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