Clinical and pathological characteristics of HIV- and HHV-8-negative Castleman disease.
Blood, 2017 Castleman disease (CD) comprises 3 poorly understood lymphoproliferative variants sharing several common histopathological features. Unicentric CD (UCD) is localized to a single region of lymph nodes.
Yu L +16 more
europepmc +2 more sources
Blood, 2017 Human herpesvirus-8 (HHV-8)-negative, idiopathic multicentric Castleman disease (iMCD) is a rare and life-threatening disorder involving systemic inflammatory symptoms, polyclonal lymphoproliferation, cytopenias, and multiple organ system dysfunction ...
Fajgenbaum DC +37 more
europepmc +2 more sources
HHV-8 reduces dendritic cell migration through down-regulation of cell-surface CCR6 and CCR7 and cytoskeleton reorganization [PDF]
Virology Journal, 2012 For an efficient immune response against viral infection, dendritic cells (DCs) must express a coordinate repertoire of receptors that allow their recruitment to the sites of inflammation and subsequently to the secondary lymphoid organs in response to ...
Mara Cirone +8 more
openalex +2 more sources
Prevalence and Risk Factors of Human Herpes Virus Type 8 (HHV-8), Human Immunodeficiency Virus-1 (HIV-1), and Syphilis among Female Sex Workers in Malindi, Kenya [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2019 The prevalence of Human Herpes Virus type 8 (HHV-8), Human Immunodeficiency virus (HIV), and syphilis is high in Sub-Saharan Africa. Studies on HHV-8 in Kenya are few and data on its coinfection with HIV and syphilis scanty.
M. M. Nzivo +4 more
doaj +2 more sources
Blood, 2012 Human herpes virus 8 (HHV-8) or Kaposi sarcoma-associated herpes virus is the etiologic agent of Kaposi sarcoma, primary effusion lymphoma, and plasma cell-type multicentric Castleman disease (MCD).
Jan Suthaus +8 more
openalex +3 more sources
European Journal of Histochemistry, 2009 Kaposi’s Sarcoma (KS) is an angioproliferative disease associated with human herpesvirus 8 (HHV-8) infection.We have characterized the morphologic and phenotypic modifications of HUVEC in a model of productive HHV-8 infection.
C Foglieni +6 more
doaj +2 more sources
High Human Herpesvirus 8 (HHV-8) Prevalence, Clinical Correlates and High Incidence among Recently HIV-1-Infected Subjects in Sao Paulo, Brazil [PDF]
PLoS ONE, 2009 Background Human herpesvirus 8 (HHV-8) is the etiological agent for Kaposi Sarcoma, which occurs especially in HIV-infected subjects. HHV-8 infection and its clinical correlates have not been well characterized in recently HIV-1-infected subjects ...
M. D. Batista +8 more
semanticscholar +5 more sources
Incidence of Human Herpesvirus 8 (HHV-8) infection among HIV-uninfected individuals at high risk for sexually transmitted infections [PDF]
BMC Infectious Diseases, 2007 BackgroundThe occurrence of, and risk factors for, HHV-8 infection have yet to be definitively determined, particularly among heterosexual individuals with at-risk behavior for sexually transmitted infections (STI).
M. Giuliani +6 more
semanticscholar +5 more sources
Human Herpesvirus 8 Seroprevalence, China [PDF]
Emerging Infectious Diseases, 2012 To summarize the seroprevalence of human herpesvirus 8 (HHV-8) in mainland China, we conducted a systematic review and meta-analysis based on available literature.
Na He +6 more
doaj +5 more sources
Development of real-time NASBA assays with molecular beacon detection to quantify mRNA coding for HHV-8 lytic and latent genes [PDF]
, 2002 BACKGROUND: Human herpesvirus-8 (HHV-8) is linked to the pathogenesis of Kaposi's sarcoma (KS), and the HHV-8 DNA load in peripheral blood mononuclear cells (PBMC) is associated with the clinical stage of KS.
Abeltje M. Polstra +2 more
openalex +7 more sources