Results 31 to 40 of about 5,611,155 (244)

Analysis of the ORFK1 hypervariable regions reveal distinct HHV-8 clustering in Kaposi’s sarcoma and non-Kaposi’s cases

Journal of experimental & clinical cancer research : CR, 2015
BackgroundClassical Kaposi’s Sarcoma (cKS) is a rare vascular tumor, which develops in subjects infected with Human Herpesvirus-8 (HHV-8). Beside the host predisposing factors, viral genetic variants might possibly be related to disease development.
P. Cordiali‐Fei, E. Trento, Marta Giovanetti, A. Lo Presti, A. Latini, M. Giuliani, G. D'Agosto, V. Bordignon, E. Cella, F. Farchi, C. Ferraro, I. Lesnoni La Parola, C. Cota, I. Sperduti, A. Vento, A. Cristaudo, M. Ciccozzi, F. Ensoli   +17 more
semanticscholar   +1 more source

Prospective study of human herpesvirus 8 oral shedding, viremia, and serological status among human immunodeficiency virus seropositive and seronegative individuals in Sao Paulo, Brazil

Journal of Oral Microbiology, 2017
Human herpesvirus 8 (HHV-8) is a gamma-herpesvirus and etiological agent of all forms of Kaposi sarcoma (KS). Saliva may play an important role in HHV-8 transmission in specific populations.
Paulo H. Braz-Silva, Tania R. Tozetto-mendoza, Laura M. Sumita, Wilton Freire, Michelle Palmieri, Alan M. do Canto, Vivian I. Avelino-Silva, Marina Gallottini, Philippe Mayaud, Claudio S. Pannuti   +9 more
doaj   +1 more source

Human Herpesvirus 8 in Australia: DNAemia and Cumulative Exposure in Blood Donors

Viruses, 2022
Human herpesvirus 8 (HHV-8), the causative agent of Kaposi’s sarcoma, multicentric Castleman’s disease and primary effusion lymphoma, predominantly manifests in immunocompromised individuals.
David J. Speicher, Jesse J. Fryk, Victoria Kashchuk, Helen M. Faddy, Newell W. Johnson   +4 more
doaj   +1 more source

iNKT and memory B-cell alterations in HHV-8 multicentric Castleman disease.

Blood, 2017
Human herpesvirus 8 (HHV-8) is the causative agent of Kaposi sarcoma (KS) and multicentric Castleman disease (MCD), a life-threatening, virally induced B-cell lymphoproliferative disorder.
Zineb Sbihi, A. Dossier, D. Boutboul, L. Galicier, C. Parizot, Amandine Emarre, B. Hoareau, N. Dupin, A. Marcelin, A. Oudin, C. Fieschi, F. Agbalika, B. Autran, É. Oksenhendler, G. Carcelain   +14 more
semanticscholar   +1 more source

Seroepidemiology and phylogenetic analysis of human herpesvirus type 8 in injection drug users and men who have sex with men in northern Taiwan

Journal of International Medical Research, 2020
Objectives Human herpesvirus 8 (HHV-8) is transmissible and causes Kaposi’s sarcoma and other malignancies. This study analyzed the seroepidemiology and phylogeny of HHV-8 among 515 injection drug users (IDUs) and 229 men who have sex with men (MSM) in ...
Yuan-Ming Lee, Pei-Shih Hung, Cheng-Wen Lin   +2 more
doaj   +1 more source

Durable remission of both multicentric Castleman's disease and Kaposi's sarcoma with valganciclovir, rituximab and liposomal doxorubicin in an HHV‐8‐positive, HIV‐negative patient

Journal of Clinical Pharmacy and Therapeutics, 2017
Human herpesvirus‐8 (HHV‐8)‐positive, HIV‐negative multicentric Castleman's disease is a rare lymphoproliferative disorder with no standardized treatment.
C. Murphy, Eliza A Hawkes, Fiona Chionh, Geoff Chong   +3 more
semanticscholar   +1 more source

HHV-8-unrelated primary effusion-like lymphoma associated with clonal loss of inherited chromosomally-integrated human herpesvirus-6A from the telomere of chromosome 19q

Scientific Reports, 2016
Primary effusion lymphomas (PEL) are associated with human herpesvirus-8 (HHV-8) and usually occur in immunocompromised individuals. However, there are numerous reports of HHV-8-unrelated PEL-like lymphomas with unknown aetiology. Here we characterize an
E. Zhang, V. Cotton, Alberto Hidalgo-Bravo, Y. Huang, Adam J. Bell, Ruth F. Jarrett, G. Wilkie, A. Davison, Ellie P. Nacheva, R. Siebert, A. Majid, Inga Kelpanides, S. Jayne, M. Dyer, N. Royle   +14 more
semanticscholar   +1 more source

Human herpes virus 8 antibodies in HIV-positive patients in Surabaya, Indonesia

Infectious Disease Reports, 2020
Background: Human herpesvirus 8 (HHV-8) infection is etiologically related to Kaposi’s sarcoma. Antibodies directed against HHV-8 can be detected in 80%–95% of HIV-seropositive patients with KS. HHV-8 serological tests have been done in several countries
Devi Oktafiani, Ni Luh Ayu Megasari, Elsa Fitriana, Nasronudin, Maria Inge Lusida, Soetjipto   +5 more
doaj   +1 more source

Human herpesvirus-8 infection leads to expansion of the preimmune/natural effector B cell compartment.

PLoS ONE, 2010
BackgroundHuman herpesvirus-8 (HHV-8) is the etiological agent of Kaposi's sarcoma (KS) and of some lymphoproliferative disorders of B cells. Most malignancies develop after long-lasting viral dormancy, and a preventing role for both humoral and cellular
Silvia Della Bella, Adriano Taddeo, Elena Colombo, Lucia Brambilla, Monica Bellinvia, Fabrizio Pregliasco, Monica Cappelletti, Maria Luisa Calabrò, Maria Luisa Villa   +8 more
doaj   +1 more source

Genotypic distribution of HHV-8 in AIDS individuals without and with Kaposi sarcoma: Is genotype B associated with better prognosis of AIDS-KS?

Medicine, 2016
AIDS-associated Kaposi's sarcoma (AIDS-KS) caused by human herpes virus 8 (HHV-8) is the most severe and resistant form of KS tumor. Our aim was to verify whether there is an association between HHV-8 variability and development of AIDS-KS in Brazil by ...
T. R. Tozetto-Mendoza, K. Ibrahim, A. Tateno, Cristiane Mendes de Oliveira, L. M. Sumita, Maria C Sanchez, E. Luna, L. C. Pierrotti, J. Drexler, P. Braz-Silva, C. Pannuti, C. Romano   +11 more
semanticscholar   +1 more source