Results 41 to 50 of about 5,611,155 (244)

Establishment of HHV-8-positive and HHV-8-negative lymphoma cell lines from primary lymphomatous effusions [PDF]

International Journal of Cancer, 1997
Primary lymphomatous effusions are represented by cases of non-Hodgkin's lymphoma (NHL) which grow in liquid phase in the serous body cavities in the absence of solid tumour masses. Based on morphologic, immunophenotypic, virologic and genotypic features, primary lymphomatous effusions are distinguished into body cavity-based lymphoma (BCBL), Burkitt's
Carbone A, Cilia AM, Gloghini A, Canzonieri V, Pastore C, Todesco M, Cozzi M, Perin T, Volpe R, Pinto A, Gaidano G   +10 more
openaire   +4 more sources

HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy.

Blood, 2014
Multicentric Castleman's disease (MCD) describes a heterogeneous group of disorders involving proliferation of morphologically benign lymphocytes due to excessive proinflammatory hypercytokinemia, most notably of interleukin-6.
D. Fajgenbaum, F. van Rhee, C. Nabel
semanticscholar   +1 more source

Genotypic distribution of HHV-8 in AIDS individuals without and with Kaposi sarcoma

Medicine, 2016
AIDS-associated Kaposi's sarcoma (AIDS-KS) caused by human herpes virus 8 (HHV-8) is the most severe and resistant form of KS tumor. Our aim was to verify whether there is an association between HHV-8 variability and development of AIDS-KS in Brazil by ...
T. R. Tozetto-Mendoza, K. Ibrahim, A. Tateno, C. M. de Oliveira, L. M. Sumita, Maria C Sanchez, E. Luna, L. C. Pierrotti, J. Drexler, P. Braz-Silva, C. Pannuti, C. Romano   +11 more
semanticscholar   +1 more source

HPV Infection, but Not EBV or HHV-8 Infection, Is Associated with Salivary Gland Tumours

BioMed Research International, 2015
Benign and malignant salivary gland tumours are clinically heterogeneous and show different histology. Little is known about the role of human herpes virus 8 (HHV-8), Epstein-Barr virus (EBV), and human papillomavirus (HPV) infection in salivary gland ...
Maja Hühns, G. Simm, A. Erbersdobler, A. Zimpfer   +3 more
semanticscholar   +1 more source

Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complex. [PDF]

PLoS Pathogens, 2018
Human herpesvirus 8 (HHV-8) is causally related to human malignancies. HHV-8 latent viral FLICE-inhibitory protein (vFLIP) is a viral oncoprotein that is linked to pathogenesis, but how its expression is regulated is largely unknown.
Young Bong Choi, Yeeun Choi, Edward William Harhaj   +2 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

HHV-8-positive and EBV-positive intravascular lymphoma: an unusual presentation of extracavitary primary effusion lymphoma.

American Journal of Surgical Pathology, 2014
Intravascular lymphomas are rare and aggressive hematolymphoid tumors. Here, we describe a human herpesvirus type-8 (HHV-8)/Kaposi sarcoma-associated herpesvirus-positive and Epstein-Barr virus (EBV)-positive intravascular lymphoma.
G. Crane, R. Ambinder, Courtney M. Shirley, E. Fishman, Y. Kasamon, J. Taube, M. Borowitz, A. Duffield   +7 more
semanticscholar   +1 more source

Detection of human herpesvirus 8 by quantitative polymerase chain reaction: development and standardisation of methods

BMC Infectious Diseases, 2012
Background Human herpesvirus 8 (HHV-8), the aetiological agent of Kaposi’s sarcoma (KS), multicentric Castleman’s disease (MCD), and primary effusion lymphoma (PEL) is rare in Australia, but endemic in Sub-Saharan Africa, parts of South-east Asia and ...
Speicher David J, Johnson Newell W
doaj   +1 more source

Epidemiology and Genetic Variability of HHV-8/KSHV in Pygmy and Bantu Populations in Cameroon

PLoS Neglected Tropical Diseases, 2014
Background Kaposi's sarcoma associated herpesvirus (KSHV/HHV-8) is the causal agent of all forms of Kaposi sarcoma. Molecular epidemiology of the variable K1 region identified five major subtypes exhibiting a clear geographical clustering.
E. Betsem, O. Cassar, Philippe V. Afonso, A. Fontanet, A. Froment, A. Gessain   +5 more
semanticscholar   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source