Results 91 to 100 of about 13,947 (241)

Bidirectional Risk Association Between Hidradenitis Suppurativa and Inflammatory Bowel Disease

Acta Dermato-Venereologica
Hidradenitis suppurativa is an inflammatory skin disease of the pilosebaceous unit encompassing painful, recurrent, and malodorous abscesses, inflammatory nodules, dermal sinus tracts, and cicatrices.
Louise Lönndahl, Maria Najeeb, Hassan Killasli, Lennart Emtestam, Ralf J. Ludwig, Philip Curman   +5 more
doaj   +1 more source

Clinical and Ultrasonographic Profile of Adalimumab-treated Hidradenitis Suppurativa Patients: A Real-life Monocentric Experience

Acta Dermato-Venereologica, 2020
Ultrasonography has proven useful for diagnosis and treatment monitoring in patients with hidradenitis suppurativa. The aim of this study was to assess the clinical response to adalimumab using ultrasound findings.
Andrea Chiricozzi, Giulia Giovanardi, Simone Garcovich, Dalma Malvaso, Giacomo Caldarola, Barbara Fossati, Cristina Guerriero, Clara De Simone, Ketty Peris   +8 more
doaj   +1 more source

Familial hidradenitis suppurativa is associated with an increased prevalence of metabolic and cardiovascular comorbidity

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Suzan Al‐Gburi, Niloofar Ghaffari, Michael Schultheis, Wolfram Jaschke, Florian Regensberger, Fiona André, Piotr K Krajewski, Alexandra Strobel, Petra Staubach, Katharina Hennig, Lukasz Matusiak, Simone Garcovich, Hans Bayer, Uwe Kirschner, Georgios Nikolakis, Jacek C Szepietowski, Matthias Schmuth, Esther von Stebut   +17 more
wiley   +1 more source

Long‐term efficacy of biologics in moderate‐to‐severe hidradenitis suppurativa: A systematic review and MAIC

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A matching‐adjusted indirect treatment comparison (MAIC) was conducted, comparing approved biologics for long‐term (48–52 weeks) treatment of moderate‐to‐severe hidradenitis suppurativa (HS). Using weighted patient‐level trial data allowed re‐estimation of relative bimekizumab efficacy compared with aggregate secukinumab and adalimumab trial data ...
Thrasyvoulos Tzellos, Vincent Piguet, Michael Frank Mørup, Leah Davis, Vanessa Taieb, Sandeep Kiri, Victoria Shodimu, Abby Paine, Brian Kirby, Haley B. Naik   +9 more
wiley   +1 more source

Severe hidradenitis suppurativa exacerbation in temporal association with PD‐1 blockade in cutaneous squamous cell carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Nadine Larissa Fergen, Konstantin Maria Steinke, Nicole Kreuzberg, Esther von Stebut, Cindy Franklin   +4 more
wiley   +1 more source

Hidradenitis suppurativa and vasculitis: A case series and literature review of a rare association

SAGE Open Medical Case Reports, 2019
Hidradenitis suppurativa is a chronic inflammatory skin disease with dysregulation of the immune system. Its pathophysiology is not clear, and it has been reported in association with various inflammatory disorders such as pyoderma gangrenosum, arthritis,
Afsaneh Alavi, Eran Shavit, Jeannine Archer, Christian Pagnoux   +3 more
doaj   +1 more source

Bimekizumab efficacy using IHS4 outcomes in hidradenitis suppurativa: Results from BE HEARD I and II

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The majority of bimekizumab‐treated patients shifted from severe to mild and moderate IHS4 stages, and nearly 25% achieved an IHS4 of 0 by Week 48. Bimekizumab led to clinically meaningful improvements across IHS4 outcome measures. These data highlight an opportunity to address the need for effective treatments against draining tunnels.
Thrasyvoulos Tzellos, Evangelos J. Giamarellos‐Bourboulis, Kelsey R. van Straalen, Antonio Martorell, Brian Kirby, Afsaneh Alavi, Koremasa Hayama, Saakshi Khattri, Wayne Gulliver, Christopher J. Sayed, Leah Davis, Robert L. Rolleri, Christina Crater, Ingrid Pansar, Jérémy Lambert, Christos C. Zouboulis   +15 more
wiley   +1 more source

Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association [PDF]

Fabrizio Martora,* Teresa Battista,* Antonella Giordano, Luca Potestio, Matteo Megna Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy*These authors contributed equally to this ...
Giordano A, Battista T, Megna M, Potestio L, Martora F   +4 more
core  

Improvement of overlapping hidradenitis suppurativa and ankylosing spondylitis after the introduction of adalimumab [PDF]

, 2016
Hidradenitis suppurativa is a chronic inflammatory disorder characterized by occlusion of the follicular pilosebaceous units of the skin. The treatment options are sometimes very limited and unpleasant odor and abundant drainage complicate the disease ...
Marko Barešić, Bosnić, Dubravka, Branimir Žarković, Maja Zarkovic, Branimir Anić, Dubravka Bosnić, Žarković, Branimir, Barešić, Marko, Anić, Branimir, Žarković, Maja   +9 more
core   +1 more source

Genomic and proteomic insights into hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou, Emmanouil Stylianakis, Isis Ricaño‐Ponce, Nick Keur, Theodora Kanni, Dimitra Stergianou, Mihai G. Netea, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis   +8 more
wiley   +1 more source