Results 111 to 120 of about 11,461 (257)
The SKINERGY study will investigate six immune‐mediated inflammatory skin diseases through a nationwide collaboration across all Dutch university medical centres. Involving 720 patients and 120 healthy volunteers, it is aimed at generating a high‐quality dataset to identify biomarkers that enable personalized treatment strategies and improved disease ...
N. G. Koster +68 more
wiley +1 more source
Radiology‐Dermatology Diagnostic Variation in Skin and Soft Tissue Infections: A Cohort Analysis
International Journal of Dermatology, EarlyView.
Varshita Chirumamilla +5 more
wiley +1 more source
Bimekizumab efficacy using IHS4 outcomes in hidradenitis suppurativa: Results from BE HEARD I and II
The majority of bimekizumab‐treated patients shifted from severe to mild and moderate IHS4 stages, and nearly 25% achieved an IHS4 of 0 by Week 48. Bimekizumab led to clinically meaningful improvements across IHS4 outcome measures. These data highlight an opportunity to address the need for effective treatments against draining tunnels.
Thrasyvoulos Tzellos +15 more
wiley +1 more source
Genomic and proteomic insights into hidradenitis suppurativa
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou +8 more
wiley +1 more source
Skin Homeostasis is Impaired in Hidradenitis Suppurativa Lesions: A Comparative Study
Introduction: Hidradenitis suppurativa (HS) is a chronic skin disease whose impact on skin homeostasis has not been adequately studied at present. Knowledge about how skin function changes in these patients, and could be of interest not only to improve ...
A. Soto-Moreno +4 more
doaj +1 more source
OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta +4 more
wiley +1 more source
Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association
Fabrizio Martora,* Teresa Battista,* Antonella Giordano, Luca Potestio, Matteo Megna Dermatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy*These authors contributed equally to this ...
Giordano A +4 more
core
Significant upregulated genes in hidradenitis suppurativa.
Significant upregulated genes in hidradenitis suppurativa.
Maria I. Morasso (255438) +9 more
core +1 more source

