Results 101 to 110 of about 3,381,889 (354)
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Hierarchical clustering using the arithmetic-harmonic cut: complexity and experiments.
PLoS ONE, 2010 Clustering, particularly hierarchical clustering, is an important method for understanding and analysing data across a wide variety of knowledge domains with notable utility in systems where the data can be classified in an evolutionary context.
Romeo Rizzi +3 more
doaj +1 more source
Shared Differential Clustering across Single-cell RNA Sequencing Datasets with the Hierarchical Dirichlet Process [PDF]
, 2022 Jinlu Liu, Sara Wade, Natalia Bochkina
openalex +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Hierarchical Clustering and the Butcher-Oemler Effect
, 1994 We show that the rapid evolution in the fraction of blue, star-forming galaxies seen in clusters as a function of redshift (the Butcher-Oemler effect) can be explained very simply if structure formation in the universe proceeeds hierarchically.
Kauffmann, Guinevere
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
An Improved K-means Clustering Algorithm Applicable to Massive High-dimensional Matrix Datasets
ITM Web of Conferences, 2017 Since K-means clustering algorithm is easy to implement and high efficient, it has been widely used in cluster analysis of massive datasets. The value of k is difficult to determine in advance and the randomness of choosing initial centers leads to a ...
Li Dong-Yuan, Cao Cai-Feng
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin +12 more
wiley +1 more source
On Randomly Projected Hierarchical Clustering with Guarantees
, 2014 Hierarchical clustering (HC) algorithms are generally limited to small data instances due to their runtime costs. Here we mitigate this shortcoming and explore fast HC algorithms based on random projections for single (SLC) and average (ALC) linkage ...
Schneider, Johannes, Vlachos, Michail
core +1 more source