Results 301 to 310 of about 3,381,889 (354)

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Hierarchical clustering of gut microbiota based on a Euclidean distance matrix across ethnicities and geographic locations, with age annotations.

Tanapon Seetaraso (19847626), Lucsame Gruneck (22230253), Vasana Jinatham (11816513), Sitanan Kantakat (22379033), Marie-Lou Albert (22379036), Phatthanaphong Therdtatha (5437757), Angkhana Inta (4536535), Metawee Srikummool (11226185), Jatupol Kampuansai (589980), Siam Popluechai (5437769)   +9 more
openalex   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Dendrogram of the hierarchical cluster analysis applied to the identification of CTs used with pressure, based on three clusters.

Olivier Touzé (22133040), Veerle Rots (2548492)   +1 more
openalex   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

Advanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu, Linling Li, Ting Luo, Gan Huang, Li Zhang, Benjamin Becker, Zhen Liang   +6 more
wiley   +1 more source

Disease-associated immune cell endotypes in anti-MDA5-positive dermatomyositis using unbiased hierarchical clustering. [PDF]

Front Immunol
Guo R, Yang Y, Gu L, Li X, Ma Y, Liu X, Lu L.   +6 more
europepmc   +1 more source

Hierarchical Cluster Approach to Identify High-End Chinese Tourist Behavior: A Case Study in Phuket, Thailand

Thanatat Chitpipat, Therdchai Choibamroong   +1 more
openalex   +2 more sources

Exploring Burnout among Nursing Students in Bangalore: A t-Distributed Stochastic Neighbor Embedding Analysis and Hierarchical Clustering in Cross-Sectional Data. [PDF]

Nurs Rep
Sebastian M, De Maria M, Caruso R, Rocco G, Di Pasquale C, Magon A, Conte G, Stievano A.   +7 more
europepmc   +1 more source