Results 211 to 220 of about 20,722 (263)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Hyperledger Fabric-Powered Digital Identity Scheme: Transforming CIA-Triad Security in IoMT Integrated Healthcare Eco-System. [PDF]

Blockchain Healthc Today
Jena S, Barik RC, Padhan S.
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Secure and scalable dual blockchain and IPFS driven IoT ecosystem for next gen healthcare systems. [PDF]

Sci Rep
Mallick SR, Lenka RK, Sobhanayak S.
europepmc   +1 more source

Fully secure and hierarchical identity based signature for automatic dependent surveillance broadcast systems. [PDF]

Sci Rep
Yu Q.
europepmc   +1 more source

Quantum-resilient cross-trust evaluation for zero trust 5G security. [PDF]

Sci Rep
Jeysuriya K, Renjith PN, Sudhakaran G.
europepmc   +1 more source

A triple-layer authentication framework with elliptic curve cryptography for securing IoT-assisted wireless sensor networks. [PDF]

PLoS One
Alanazi MD.
europepmc   +1 more source

A comparative performance analysis of fully homomorphic and attribute-based encryption schemes. [PDF]

Sci Rep
More KD, Pramod D.
europepmc   +1 more source

A cross-chain model for warehouse receipts in port supply chain based on notary mechanism and ShangMi cryptographic algorithms. [PDF]

Sci Rep
Chen Y, Ou W, Pang M, Ma J, Yue Q, Han W.   +5 more
europepmc   +1 more source