Results 61 to 70 of about 1,685,765 (286)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

A case study where memory disorder became obvious after disturbance of consciousness

open access: yesJournal of Human Environmental Studies, 2018
Some rehabilitative approaches were taken toward a male patient in his 40's by following the processes of cognitive dysfunction as a form of information-processing.
Makoto Hirumuta   +4 more
doaj   +1 more source

A hierarchical framework for estimating abundance and population growth from imperfectly observed removals

open access: yesEcosphere, 2020
Estimating abundance and growth of animal populations are central tasks in ecology and natural resource management. Removal models for estimating abundance have a long history in applied ecology, and recent developments provided hierarchical extensions ...
Bryan S. Stevens   +3 more
doaj   +1 more source

A Hierarchical Probability Model of Colon Cancer [PDF]

open access: yes, 2010
We consider a model of fixed size $N = 2^l$ in which there are $l$ generations of daughter cells and a stem cell. In each generation $i$ there are $2^{i-1}$ daughter cells.
Kelly, Michael
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Long‐term trends and drought: Spatiotemporal variation in juvenile sex ratios of North American ducks

open access: yesEcology and Evolution, 2022
Sex ratios affect population dynamics and individual fitness, and changing sex ratios can be indicative of shifts in sex‐specific survival at different life stages. While climate and landscape changes alter sex ratios of wild bird populations, long‐term,
Sage L. Ellis   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Understanding spatially explicit capture–recapture parameters for informing invasive animal management

open access: yesEcosphere, 2022
Spatially explicit capture–recapture modeling is used to estimate population density to enhance our ecological understanding and management of wildlife populations. The two primary parameters estimated in the capture process of these models are σ and g0.
Dean P. Anderson   +3 more
doaj   +1 more source

Singular Spectrum and Recent Results on Hierarchical Operators

open access: yes, 2018
We use trace class scattering theory to exclude the possibility of absolutely continuous spectrum in a large class of self-adjoint operators with an underlying hierarchical structure and provide applications to certain random hierarchical operators and ...
von Soosten, Per, Warzel, Simone
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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