Results 61 to 70 of about 19,320,239 (252)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Tạp chí Khoa học và Công nghệThe escalating challenge of antibiotic resistance has driven the innovation of new antibacterial and antifouling materials. Recent developments focus on nature-inspired topographical engineering and nanostructured surfaces to combat resistant bacteria ...
Yen Dang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Curl-conforming hierarchical vector bases for triangles and tetrahedra [PDF]
, 2011 A new family of hierarchical vector bases is proposed for triangles and tetrahedra. These functions span the curl-conforming reduced-gradient spaces of Nédélec.
Peterson A. F. +9 more
core +1 more source
Frontiers in Human Neuroscience, 2017 We investigated the role of culture in processing hierarchical syntactic structures in music. We examined whether violation of non-local dependencies manifest in event related potentials (ERP) for Western and Iranian excerpts by recording EEG while ...
Haleh Akrami +2 more
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Advanced Materials Interfaces, 2023 In this study, the wetting behavior of microstructured polyethylene terephthalate (PET) foils for polar and nonpolar liquids produced by plate‐to‐plate hot embossing is investigated.
Felix Bouchard +2 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Achieving k-anonymity by clustering in attribute hierarchical structures
, 2006 . Individual privacy will be at risk if a published data set is not properly deidentified. k-anonymity is a major technique to de-identify a data set. A more general view of k-anonymity is clustering with a constraint of the minimum number of objects in ...
Raymond Chi-wing Wong +7 more
core +1 more source