Results 41 to 50 of about 15,227,697 (301)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

8-bit states in 2D floating-gate memories using gate-injection mode for large-scale convolutional neural networks

Nature Communications
The fast development of artificial intelligence has called for high-efficiency neuromorphic computing hardware. While two-dimensional floating-gate memories show promise, their limited state numbers and stability hinder practical use.
Yuchen Cai, Jia Yang, Yutang Hou, Feng Wang, Lei Yin, Shuhui Li, Yanrong Wang, Tao Yan, Shan Yan, Xueying Zhan, Jun He, Zhenxing Wang   +11 more
doaj   +1 more source

Coordinating constituents in hierarchical discourse structures

Círculo de Lingüística Aplicada a la Comunicación
The information needed in discourse to connect each constituent to the preceding one in a text is added from the discourse context in the text. A unit with initial y “and” is a coordinating constituent but it has subordinating properties, as shown in ...
Joaquín Garrido
doaj   +1 more source

A storage scheme for hierarchic structures [PDF]

The Computer Journal, 1974
The representation of a tree by a right-threaded binary tree, as described for example by Knuth (1968, pp. 332 ff), is extended to permit representation of ‘hierarchic structures’ (directed graphs without circuits). This representation corresponds to a compact storage scheme useful both for ascent and descent of the hierarchy.
W. F. Smyth, E. Radaceanu
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Metallic tellurium for p-type contacts of two-dimensional MoTe2 field-effect transistors

Nature Communications
While significant progress has been made in the fabrication of n-type contacts for two-dimensional field-effect transistors (2D FETs), the development of high-performance p-type counterparts using compatible techniques remains insufficient to realize ...
Yuhan Zhu, Feng Wang, Shuhui Li, Chen Shen, Yuchen Cai, Tao Yan, Fuyuan Zhang, Yanrong Wang, Xueying Zhan, Kai Xu, Hao Wang, Hongbin Zhang, Zhenxing Wang, Jun He   +13 more
doaj   +1 more source

Specification and Verification Method of Parallel Hierarchical Timed Automata by Predicate Abstraction and Refinement

IEEE Access
Embedded systems have three major features: real-time, parallel and hierarchical. Therefore, we specified an embedded system as a hierarchically structured timed automata operating in parallel.
Satoshi Yamane
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source