Results 61 to 70 of about 1,024 (133)

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, Volume 4, Issue 3, September 2026.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Recent Advancements in Drug Delivery Across the Blood–Brain Barrier in Amyotrophic Lateral Sclerosis (ALS)

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Progressive BBB/BSCB dysfunction is increasingly recognized as both a pathological feature and a therapeutic barrier in ALS. Novel delivery technologies and barrier‐restoration strategies may enhance CNS drug exposure, improve the efficacy of disease‐modifying therapies, and advance ALS treatment. ABSTRACT Background Amyotrophic lateral sclerosis (ALS)
Nitesh Sanghai, Kaitlyn Pierce, Nidhi Sharma, Sasha Leggett, Tara Chand Yadav, Pegah Masrori, Devi Atukorallaya, Senthilnathan Palaniyandi, Paul C. Marcogliese, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Feasibility, safety and efficacy of high intensity focused ultrasound ablation as a preoperative treatment for challenging hysteroscopic myomectomy

International Journal of Hyperthermia
Purpose To investigate the feasibility, safety and efficacy of high intensity focused ultrasound ablation (HIFU) as a preoperative treatment for challenging hysteroscopic myomectomies.Materials and methods A total of 75 patients diagnosed with types 0 ...
Yuchun He, Min Wu, Xu Guo, Feng Ran, Haiyan Li, Daibi Zhang, Yaqin Wang, Jin Zeng, Xuelian Chen, Linghui Zhai, Xiaohui Li, Tingting Lei   +11 more
doaj   +1 more source

The value of acoustic radiation force impulse imaging in preoperative prediction for efficacy of high-Intensity focused ultrasound uterine fibroids ablation

International Journal of Hyperthermia, 2020
Objective To investigate the application value of acoustic radiation force impulse imaging in preoperative prediction for efficacy of High-Intensity Focused Ultrasound uterine fibroids ablation Methods A prospective study was conducted on 32 women (41 ...
Dan-ling Zhang, Xin-xiu Liu, Jian-qing Tang, Song-song Wu, Ning Lin, Gui-sheng Ding, Xiao-li Pan, Sheng Chen   +7 more
doaj   +1 more source

Robot-assisted Ultrasound-guided Tracking of Anatomical Structures for the Application of Focused Ultrasound

Current Directions in Biomedical Engineering, 2020
High intensity focused ultrasound is used as a surgical tool to treat completely non-invasively several diseases. Examples of clinical applications are uterine fibroids, prostate cancer, thyroid nodules, and varicose veins.
Unger Michael, Berger Johann, Gerold Bjoern, Melzer Andreas   +3 more
doaj   +1 more source

A computational tool for evaluating HIFU safety.

Annali dell'Istituto superiore di sanita, 2017
High Intensity Focused Ultrasound (HIFU) is a noninvasive treatment for therapeutic applications, in particular the treatment of either benign or malignant tumor lesions. HIFU treatment is based on the power of a focused ultrasound beam to locally heat biological tissues over a necrotic level with minimal impact on the surrounding tissues.
Silvia Pozzi, Cristian Borrazzo, Marco Carnì, Elisabetta Di Castro, Stefano Valentini, Barbara Caccia   +5 more
openaire   +2 more sources

Real-Time Reconstruction of HIFU Focal Temperature Field Based on Deep Learning

BME Frontiers
Objective and Impact Statement: High-intensity focused ultrasound (HIFU) therapy is a promising noninvasive method that induces coagulative necrosis in diseased tissues through thermal and cavitation effects, while avoiding surrounding damage to ...
Shunyao Luan, Yongshuo Ji, Yumei Liu, Linling Zhu, Haoyu Zhou, Jun Ouyang, Xiaofei Yang, Hong Zhao, Benpeng Zhu   +8 more
doaj   +1 more source

Investigation of HIFU-induced anti-tumor immunity in a murine tumor model

Journal of Translational Medicine, 2007
Background High intensity focused ultrasound (HIFU) is an emerging non-invasive treatment modality for localized treatment of cancers. While current clinical strategies employ HIFU exclusively for thermal ablation of the target sites, biological ...
Lyerly H Kim, Morse Michael A, Pua Eric C, Sankin Georgy N, Liu Yunbo, Yang Xiao, Hu Zhenlin, Clay Timothy M, Zhong Pei   +8 more
doaj   +1 more source

A robotic approach to HIFU based neurosurgery [PDF]

, 1998
The use of robotics in surgical interventions not only has the potential for minimally invasive surgical procedures but can improve performance and result in reduced operative time and post-operative trauma/recovery. This paper describes the concept of a robotic based High Intensity Focused Ultrasound system as a neuro-surgical tool for the destruction
Brian L. Davies, Sunita Chauhan, Mike J. S. Lowe   +2 more
openaire   +2 more sources

Retracted: High‐intensity focused ultrasound inhibits invasion and metastasis of colon cancer cells by enhancing microRNA‐124‐mediated suppression of STAT3

FEBS Open Bio, 2019
Metastasis is the primary contributor to colorectal cancer mortality. High‐intensity focused ultrasound (HIFU) is an emerging technology for tumor therapy that exerts its effects through tumor ablation, mechanical disruption, and enhancement of immune ...
Meiying Li, Guangsheng Wan, Hongjie Yu, Wei Xiong   +3 more
doaj   +1 more source