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Cognitive Impairments at High Altitudes and Adaptation

High Altitude Medicine & Biology, 2014
Abstract Xiaodan Yan. Cognitive impairments at high altitudes and adaptation. High Alt Med Biol. 15:141–145, 2014.—High altitude hypoxia has been shown to have significant impact on cognitive performance.
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Postnatal cardiopulmonary adaptations to high altitude

Respiratory Physiology & Neurobiology, 2007
Postnatal cardiopulmonary adaptations to high altitude constitute a key component of any set of responses developed to face high altitude hypoxia. Such responses are required ultimately to meet the energy demands necessary for adequate functioning at cell and organism level.
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Cardiorespiratory characteristics and adaptation to high altitudes

American Journal of Physical Anthropology, 1970
AbstractThe lowered partial pressure of oxygen at high altitude is one of the severest and most pervasive environmental stresses affecting human populations. Virtually all organ systems and physiological functions are affected by hypoxia, and only elaborate modern technology can temporarily ameliorate the hypoxic stress of altitude exposure.
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Human Genetic Adaptation to High Altitude

High Altitude Medicine & Biology, 2001
Some 140 million persons live permanently at high altitudes (>2500 m) in North, Central and South America, East Africa, and Asia. Reviewed here are recent studies which address the question as to whether genetic adaptation to high altitude has occurred.
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Human Adaptations to High Altitude

2021
Present-day inhabitants of Himalayan, Andean, and Ethiopian highlands exhibit a wide range of physiological responses to chronic hypoxemia inherent to life at high altitude. Physiological assessments and analyses throughout the past several decades suggest each population adapted distinct mechanisms for oxygen transport and utilization, which have been
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High-altitude adaptations in vertebrate hemoglobins

Respiratory Physiology & Neurobiology, 2007
Vertebrates at high altitude are subjected to hypoxic conditions that challenge aerobic metabolism. O(2) transport from the respiratory surfaces to tissues requires matching between the O(2) loading and unloading tensions and the O(2)-affinity of blood, which is an integrated function of hemoglobin's intrinsic O(2)-affinity and its allosteric ...
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Genetic Evidence for High-Altitude Adaptation in Tibet

Science, 2010
No Genetic Vertigo Peoples living in high altitudes have adapted to their situation (see the Perspective by Storz ). To identify gene regions that might have contributed to high-altitude adaptation in Tibetans,
Tatum S, Simonson   +11 more
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Adaptation to High Altitude

New England Journal of Medicine, 1971
C, Reynafarje, A, Hurtado
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The possible role of adrenomedullin in adaption to high altitude

Wiener Medizinische Wochenschrift, 2005
Diuresis and natriuresis are well-known responses to acute hypoxic exposure. Even though there have been many studies on the hormonal regulation of the hypoxic diuretic response (HDR), most of the fluid-regulating hormones showed no consistent correlation to HDR.
Bernd, Haditsch   +2 more
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Cardiopulmonary Adaptation to High Altitude

2012
The reduction in inspired oxygen pressure with increasing altitude triggers a full array of mechanisms allowing the human body to adapt to the lower oxygen availability. The adrenergic system is activated via the stimulation of peripheral chemoreceptors, leading to an increase in heart rate and cardiac output. With acclimatization, the cardiac response
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