Results 71 to 80 of about 163,557 (294)

Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation

Nature Communications, 2020
Tibetan adaptation to the high-altitude environment represents a case of natural selection during recent human evolution. Here the authors investigated the chromatin and transcriptional landscape of umbilical endothelial cells from Tibetan and Han ...
Jingxue Xin, Hui Zhang, Yaoxi He, Zhana Duren, Caijuan Bai, Lang Chen, Xin Luo, Dong-Sheng Yan, Chaoyu Zhang, Xiang Zhu, Qiuyue Yuan, Zhanying Feng, Chaoying Cui, Xuebin Qi, Ouzhuluobu, Wing Hung Wong, Yong Wang, Bing Su   +17 more
doaj   +1 more source

Comparative metabolomics analysis reveals high-altitude adaptations in a toad-headed viviparous lizard, Phrynocephalus vlangalii

Frontiers in Zoology, 2023
Extreme environmental conditions at high altitude, such as hypobaric hypoxia, low temperature, and strong UV radiation, pose a great challenge to the survival of animals.
Xuejing Zhang, Shengkang Men, Lun Jia, Xiaolong Tang, Kenneth B. Storey, Yonggang Niu, Qiang Chen   +6 more
doaj   +1 more source

Adapting to Changing Rainfall and Developing Off‐Farm Employment: Implications for the Adoption of Direct Seeding in Rice Production

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Rice is the main staple food for more than half of the world's population and the income from rice is an essential source for livelihoods of millions of households. We examine whether direct seed in rice production is an adaptation of rice farmers to rainfall changes and farm labor scarcity.
Manh Hung Do
wiley   +1 more source

How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang, Lena Kuhn, Hang Xiong, Zhanli Sun, Thomas Glauben   +4 more
wiley   +1 more source

Role of mitochondrial genetic interactions in determining adaptation to high altitude human population

Scientific Reports, 2022
Physiological and haplogroup studies performed to understand high-altitude adaptation in humans are limited to individual genes and polymorphic sites. Due to stochastic evolutionary forces, the frequency of a polymorphism is affected by changes in the ...
Rahul K. Verma, Alena Kalyakulina, Ankit Mishra, Mikhail Ivanchenko, Sarika Jalan   +4 more
doaj   +1 more source

Genomic Analysis of High-Altitude Adaptation [PDF]

Current Sports Medicine Reports, 2011
Endurance exercise and high altitude exposure share the physiological challenge of reduced oxygen supply relative to metabolic demand (e.g., 8). This similarity suggests that biological features considered to be adaptive for life at high altitude are likely also relevant for endurance exercise.
Megan J, Wilson, Colleen Glyde, Julian, Robert C, Roach   +2 more
openaire   +2 more sources

Agricultural Diversification at the Margin. Strategies and Determinants in Italian Mountain and Remote Areas

Agribusiness, EarlyView.
ABSTRACT This paper explores the convergence in on‐farm diversification strategies of agricultural holdings, between remote areas and more central ones. Using Italian farm‐level data, we explore the determinants of diversification strategies across farms.
Gianluca Grilli, Francesco Pagliacci, Paola Gatto   +2 more
wiley   +1 more source

Genetic adaptation to high altitude in the Ethiopian highlands

, 2012
Background: Genomic analysis of high-altitude populations residing in the Andes and Tibet has revealed several candidate loci for involvement in high-altitude adaptation, a subset of which have also been shown to be associated with hemoglobin levels ...
Thompson, S., William Beggs, Gurja Belay, Ranciaro, A., Sameer Soi, Charla Lambert, Sarah A Tishkoff, Simon Thompson, Soi, S., Belay, G., Alessia Ranciaro, Jarvis, J. P., Laura B Scheinfeldt, Beggs, W., Tishkoff, S. A., Abate, D., Joseph P Jarvis, Woldemeskel, D., Dawit Abate, Scheinfeldt, L. B., Lambert, C., Dawit Woldemeskel   +21 more
core   +1 more source

Introgression drives adaptation to the plateau environment in a subterranean rodent

BMC Biology
Background Introgression has repeatedly been shown to play an important role in the adaptation of species to extreme environments, yet how introgression enables rodents with specialized subterranean lifestyle to acclimatize to high altitudes is still ...
Yukun Kang, Zhicheng Wang, Kang An, Qiqi Hou, Zhiming Zhang, Junhu Su   +5 more
doaj   +1 more source

A genetic mechanism for Tibetan high-altitude adaptation [PDF]

Nature Genetics, 2014
Tibetans do not exhibit increased hemoglobin concentration at high altitude. We describe a high-frequency missense mutation in the EGLN1 gene, which encodes prolyl hydroxylase 2 (PHD2), that contributes to this adaptive response. We show that a variant in EGLN1, c.[12C>G; 380G>C], contributes functionally to the Tibetan high-altitude phenotype.
Felipe R, Lorenzo, Chad, Huff, Mikko, Myllymäki, Benjamin, Olenchock, Sabina, Swierczek, Tsewang, Tashi, Victor, Gordeuk, Tana, Wuren, Ge, Ri-Li, Donald A, McClain, Tahsin M, Khan, Parvaiz A, Koul, Prasenjit, Guchhait, Mohamed E, Salama, Jinchuan, Xing, Gregg L, Semenza, Ella, Liberzon, Andrew, Wilson, Tatum S, Simonson, Lynn B, Jorde, William G, Kaelin, Peppi, Koivunen, Josef T, Prchal   +22 more
openaire   +2 more sources