Results 141 to 150 of about 34,730 (280)
The Journal of Physiology, EarlyView.Abstract figure legend Exacerbated ATP signalling in the carotid body (CB) of spontaneously hypertensive rats (SHRs) arises from expansion of the chemosensory glomus cell compartment and reduced extracellular ATP metabolism, leading to increased purinergic drive.
Igor S. A. Felippe +11 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend This study aimed to develop a non‐invasive method for visualizing the cardiorespiratory network under baseline conditions and following isolated or combined exposure to hypoxia, exercise, and sleep deprivation. Twenty‐two healthy participants underwent assessments at rest and after normobaric hypoxia (FIO2${{F}_{{\mathrm{I ...
Cecilia Morandotti +10 more
wiley +1 more source
Mechanisms of haemoglobin mass expansion following heat stress
The Journal of Physiology, EarlyView.Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins +4 more
wiley +1 more source
A cytophotometric analysis of anterior pituitary changes in rats exposed to reduced pressure [PDF]
Adaptive cytochemical responses of hormone producing cells of rat anterior pituitary following exposure to simulated high ...
Anthony, A., Rockwell, K.
core +1 more source
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
The Journal of Physiology, EarlyView.Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo +11 more
wiley +1 more source
Endocrine and androgenic response to altitude training in professional cyclists
The Journal of Physiology, EarlyView.Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss +11 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu +6 more
wiley +1 more source
Vascular responses and wound repair in mice exposed to moderate and severe hypoxia [PDF]
Vascular responses and wound repair in mice exposed to moderate and severe ...
Anthony, A., Godish, D. R.
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Kathryn Wilsterman +6 more
wiley +1 more source