Results 191 to 200 of about 34,730 (280)

High-altitude hypoxia exacerbates gastric mucosal damage and regulates the Nrf2 signaling pathway in <i>Helicobacter pylori</i>-infected mice. [PDF]

Front Physiol
Li C, Wang X, Cui S.
europepmc   +1 more source

Respiratory control at high altitude: The chemoreceptor as a paragon of plasticity

The Journal of Physiology, EarlyView.
Jerome A. Dempsey
wiley   +1 more source

Powerful yet challenging: mechanistic niche models for predicting invasive species potential distribution under climate change

Ecography, Volume 2026, Issue 5, May 2026.
Risk assessments of invasive species present one of the most challenging applications of species distribution models (SDMs) due to the fundamental issues of distributional disequilibrium, niche changes, and truncation. Invasive species often occupy only a fraction of their potential environmental and geographic ranges, as their spatiotemporal dynamics ...
Erola Fenollosa, Sean E. H. Pang, Natalie J. Briscoe, Antoine Guisan, Roberto Salguero-Gómez   +4 more
wiley   +1 more source

Changes and monitoring technology of human heart rate and blood oxygen saturation under high-altitude hypoxia. [PDF]

Front Physiol
Liao Y, Lu D, Yang J.
europepmc   +1 more source

Downregulation of EPAS1 and EGLN1 mRNA Expression Associated With High‐Altitude Adaptive Genetic Variants in Sherpa Highlanders

Annals of Human Genetics, Volume 90, Issue 3, Page 202-214, May 2026.
ABSTRACT Background and Aims Sherpa highlanders exhibit remarkable tolerance to hypoxia, most likely due to genetic adaptations shaped by natural selection at high altitude. This study examined the roles of endothelial PAS domain protein 1 (EPAS1) and egl‐9 family hypoxia‐inducible factor 1 (EGLN1) in the genetic mechanisms underlying this adaptation ...
Yunden Droma, Fengming Yue, Masao Ota, Nobumitsu Kobayashi, Yoshiaki Kitaguchi, Masayuki Hanaoka   +5 more
wiley   +1 more source

Dimethyl fumarate alleviates inflammation during high altitude hypoxia induced acute lung injury by upregulating Nrf2/SLC7A11 pathway in ferroptosis. [PDF]

Clin Proteomics
Wang C, Guo H, Wang L, Wang Q, Liu T, Huang J, Wei Y, Wang C.   +7 more
europepmc   +1 more source

Cardiovascular Adaptation to High-Altitude Hypoxia

, 2017
Ke, Jun, Wang, Lei, Xiao, Daliao
openaire   +3 more sources

Bed rest decreases resting skeletal muscle O2 uptake and resting energy expenditure in young and elderly subjects

Experimental Physiology, Volume 111, Issue 5, Page 2599-2612, 1 May 2026.
Abstract A decrease in resting muscle O2 uptake (V̇O2m${\dot V_{{{\mathrm{O}}_2}{\mathrm{m}}}}$) described during bed rest (BR) could determine a decreased whole‐body resting energy expenditure (REE), potentially useful during prolonged spaceflights. Two groups of recreationally active men (young [Y], n = 8, age 23 ± 5 years; elderly [E], n = 10, age ...
Giovanni Baldassarre, Simone Porcelli, Lucrezia Zuccarelli, Lorenza Brocca, Noemi Arboit, Laura Gobbo, Michele Lacerenza, Alessio Marciano, Chiara Motto, Giulia Sanguin, Mladen Gasparini, Boštjan Šimunič, Rado Pišot, Marco Narici, Bruno Grassi   +14 more
wiley   +1 more source

BMAL1 modulation alleviates inflammatory responses in monocytes by targeting the Fis1-mediated mitochondrial unfolded protein response in high-altitude hypoxia. [PDF]

Cell Commun Signal
Ge YL, Xu J, Cai Y, Zhang B, He SY, Li PJ, Bu YR, Zhang L, Yu ZB, Ma H, Liu Y, Chen XW, Xie MJ.   +12 more
europepmc   +1 more source

Understanding stressors in combination: a continued challenge for human performance

Experimental Physiology, Volume 111, Issue 5, Page 2464-2475, 1 May 2026.
Abstract Personnel within occupational employment (e.g., military/emergency services) are exposed to various stressors concurrently including psychological, cognitive, physical and environmental. Historically, stressors have been considered and studied in isolation which is not representative of reality.
Katrina Hinde, Jennifer Wright, Ella Walker   +2 more
wiley   +1 more source