Effects of Inclisiran, Alirocumab, Evolocumab, and Evinacumab on Lipids: A Network Meta-Analysis
Reviews in Cardiovascular MedicineBackground: Direct comparisons between the drugs are limited, and the dosing remains debatable. Therefore, the study aims to indirectly compare the efficacy and safety of inclisiran, alirocumab, evolocumab, and evinacumab in lipid ...
Lin Zhang +5 more
doaj +1 more source
Micro Immunochemical Method for Estimating High- and Low-Density Lipoproteins [PDF]
, 1962 R.L. Searcy +3 more
openalex +1 more source
Contextualizing selection bias in Mendelian randomization: how bad is it likely to be? [PDF]
arXiv, 2018 Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor-outcome association. However, the relative importance of selection bias for Mendelian randomization compared to other potential biases is unclear.
arxiv
Interchange of Apolipoproteins between Chylomicrons and High Density Lipoproteins during Alimentary Lipemia in Man [PDF]
, 1973 Richard J. Havel +2 more
openalex +1 more source
HDL-apolipoprotein A-I exchange is independently associated with cholesterol efflux capacity
Journal of Lipid Research, 2015 HDL is the primary mediator of cholesterol mobilization from the periphery to the liver via reverse cholesterol transport (RCT). A critical first step in this process is the uptake of cholesterol from lipid-loaded macrophages by HDL, a function of HDL ...
Mark S. Borja +10 more
doaj
Hepatic endothelial lipase antiserum influences rat plasma low and high density lipoproteins in vivo [PDF]
, 1979 Timo Kuusi +2 more
openalex +1 more source
Journal of Lipid Research, 2019 NMR-based quantification of human lipoprotein (sub)classes is a powerful high-throughput method for medical diagnostics. We evaluated select proton NMR signals of serum lipoproteins for elucidating the physicochemical features and the absolute NMR ...
Daniela Baumstark +8 more
doaj
Multi-laboratory comparison of three heparin-Mn2+ precipitation procedures for estimating cholesterol in high-density lipoprotein. [PDF]
, 1978 J J Albers +12 more
openalex +1 more source
Transcriptional Regulation of the Human Hepatic Lipase Gene: Relation to Glucose and Lipid Metabolism [PDF]
, 2012 Hepatic Lipase (HL; EC 3.1.1.3) is an extracellular glycoprotein with phospholipase A1 and triacylglycerol hydrolase activity. The human HL protein is encoded by the LIPC gene on chromosome 15q21.
Deursen, D. (Diederik) van
core
A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans
Journal of Lipid Research, 2017 Reverse cholesterol transport (RCT) is thought to be an atheroprotective function of HDL, and macrophage-specific RCT in mice is inversely associated with atherosclerosis.
Marina Cuchel +22 more
doaj