Results 101 to 110 of about 1,615,130 (355)

Current guidelines for high-density lipoprotein cholesterol in therapy and future directions

open access: yesVascular Health and Risk Management, 2014
Bishnu H Subedi,1,2 Parag H Joshi,1 Steven R Jones,1 Seth S Martin,1 Michael J Blaha,1 Erin D Michos1 1Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, 2Greater Baltimore Medical Center, Baltimore, MD, USA Abstract: Many studies have ...
Subedi BH   +5 more
doaj  

The relationship between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and hyperuricaemia

open access: yesLipids in Health and Disease
Purpose The ratio of non-high-density lipoprotein cholesterol (non-HDL-c) to high-density lipoprotein cholesterol (HDL-c) (NHHR) is a novel comprehensive lipid index.
Zhaoxiang Wang   +6 more
doaj   +1 more source

Artificial High Density Lipoprotein Nanoparticles in Cardiovascular Research

open access: yesMolecules, 2019
Lipoproteins are endogenous nanoparticles which are the major transporter of fats and cholesterol in the human body. They play a key role in the regulatory mechanisms of cardiovascular events.
Karin Kornmueller   +2 more
doaj   +1 more source

High-Density Lipoprotein Particle Number

open access: yesJournal of the American College of Cardiology, 2012
Limitations in our ability to predict cardiovascular risk have fueled efforts to identify novel risk markers and to refine the measurement of traditional risk factors, such as low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C).
Daniel J. Rader, Emil M. deGoma
openaire   +3 more sources

Optimization of the Isolation Method for Large‐Scale Production of Synthetic Bacterial Vesicles for Cancer Immunotherapy

open access: yesAdvanced Therapeutics, EarlyView.
This study introduces a reliable technique for the large‐scale production of bacterial vesicles that maintain their immune‐modulating potential, enabling industrial manufacturing and clinical applications. Although other cancer immunotherapies are available, this research presents an advanced bacterial vesicle‐based therapeutic option, with scalable ...
Negar Ordouzadeh   +6 more
wiley   +1 more source

High-Density Lipoproteins and the Immune System [PDF]

open access: yesJournal of Lipids, 2013
High-density lipoprotein (HDL) plays a major role in vasodilation and in the reduction of low-density lipoprotein (LDL) oxidation, inflammation, apoptosis, thrombosis, and infection; however, HDL is now less functional in these roles under certain conditions.
openaire   +2 more sources

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

HDL-apolipoprotein A-I exchange is independently associated with cholesterol efflux capacity

open access: yesJournal of Lipid Research, 2015
HDL is the primary mediator of cholesterol mobilization from the periphery to the liver via reverse cholesterol transport (RCT). A critical first step in this process is the uptake of cholesterol from lipid-loaded macrophages by HDL, a function of HDL ...
Mark S. Borja   +10 more
doaj  

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