Results 11 to 20 of about 312,490 (311)
High-density lipoprotein is a nanoparticle, but not all nanoparticles are high-density lipoprotein [PDF]
High-density lipoprotein (HDL) is a natural nanoparticle that transports cholesterol from peripheral tissues to the liver and also transports other lipids, proteins, enzymes, and microRNAs. HDL–cholesterol levels are negatively correlated with the risk of cardiovascular events.
Zahi A. Fayad+4 more
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Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis
Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee+5 more
doaj +1 more source
Primary genetic disorders affecting high density lipoprotein (HDL)
There is extensive evidence demonstrating that there is a clear inverse correlation between plasma high density lipoprotein cholesterol (HDL-C) concentration and cardiovascular disease (CVD).
Constantine E Kosmas+5 more
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Background High-density lipoprotein cholesterol’s (HDL-C) long-held status as a cardiovascular disease (CVD) preventative has been called into question. Most of the evidence, however, focused on either the risk of death from CVD, or on single time point ...
Hye Jun Kim+5 more
doaj +1 more source
Background: Patients are treated with statins for the control of cholesterol; but statins control only low-density lipoprotein (LDL) and not non-high-density lipoprotein (non-HDL). Also, LDL is not a good coronary risk predictor.
A K Badrinath+5 more
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Alternations of Lipoprotein Profiles in the Plasma as Biomarkers of Huntington’s Disease
Alterations in lipid composition and disturbed lipoprotein metabolism are involved in the pathomechanism of Huntington’s disease (HD). Here, we measured 112 lipoprotein subfractions and components in the plasma of 20 normal controls, 24 symptomatic ...
Kuo-Hsuan Chang+5 more
doaj +1 more source
Dysfunctional high-density lipoprotein [PDF]
To address the progress of the investigation on dysfunctional high-density lipoprotein (HDL).HDL is generally considered to be an independent protective factor against cardiovascular disease. However, emerging evidence indicates that HDL can be modified under certain circumstances and lose its protective effect or even become atherogenic.
Xiang-An Li, Hong Feng
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High-density lipoprotein cholesterol: How High
The high-density lipoprotein cholesterol (HDL-C) is considered anti-atherogenic good cholesterol. It is involved in reverse transport of lipids. Epidemiological studies have found inverse relationship of HDL-C and coronary heart disease (CHD) risk.
G Rajagopal, V Suresh, Alok Sachan
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High-Density Lipoprotein and Heart Failure
The protective effect of high-density lipoprotein (HDL) on atherosclerosis is well known, and its mechanisms of action has been extensively studied. However, the impact of HDL on heart failure and its mechanisms are still controversial or unknown.
Liyun Xing+4 more
doaj +1 more source
High-Density Lipoproteins in Stroke [PDF]
Besides their well-documented function of reverse transport of cholesterol, high-density lipoproteins (HDLs) display pleiotropic effects due to their antioxidant, antithrombotic, anti-inflammatory and antiapoptotic properties that may play a major protective role in acute stroke, in particular by limiting the deleterious effects of ischaemia on the ...
Olivier Meilhac, Olivier Meilhac
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