Results 21 to 30 of about 370,627 (265)

Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.

Journal of Lipid Research, 1990
We have shown previously that low density lipoprotein (LDL) subjected to vortexing forms self-aggregates that are avidly phagocytosed by macrophages. That phagocytic uptake is mediated by the LDL receptor.
JC Khoo, E Miller, P McLoughlin, D Steinberg   +3 more
doaj   +1 more source

Utility of Non-High-Density Lipoprotein Cholesterol to High-Density Lipoprotein Cholesterol Ratio in Evaluating Incident Diabetes Risk

Diabetes, Metabolic Syndrome and Obesity, 2022
Guotai Sheng,1,* Dingyang Liu,1,* Maobin Kuang,1,* Yanjia Zhong,2 Shuhua Zhang,3 Yang Zou3 1Cardiology Department, Jiangxi Provincial People’s Hospital, Nanchang, Jiangxi Provincial, 330006, People’s Republic of China; 2Endocrinology ...
Sheng G, Liu D, Kuang M, Zhong Y, Zhang S, Zou Y   +5 more
doaj  

LDL and HDL transfer rates across peripheral microvascular endothelium agree with those predicted for passive ultrafiltration in humans

Journal of Lipid Research, 2015
The mechanisms by which LDLs and HDLs cross the vascular endothelium from plasma into interstitial fluid are not understood, and have never been studied in humans in vivo.
C. Charles Michel, M. Nazeem Nanjee, Waldemar L. Olszewski, Norman E. Miller   +3 more
doaj   +1 more source

High-Density Lipoproteins Are Bug Scavengers [PDF]

Biomolecules, 2020
Lipoproteins were initially defined according to their composition (lipids and proteins) and classified according to their density (from very low- to high-density lipoproteins—HDLs). Whereas their capacity to transport hydrophobic lipids in a hydrophilic environment (plasma) is not questionable, their primitive function of cholesterol transporter could
Meilhac, Olivier, Tanaka, Sébastien, Couret, David   +2 more
openaire   +3 more sources

Selective and independent associations of phospholipid transfer protein and hepatic lipase with the LDL subfraction distribution

Journal of Lipid Research, 2002
Phospholipid transfer protein (PLTP), hepatic lipase (HL), and lipoprotein lipase (LPL) have all been reported to be intricately involved in HDL metabolism but the effect of PLTP on the apolipoprotein B-containing lipoproteins relative to that of HL and ...
Susan J. Murdoch, Molly C. Carr, Hal Kennedy, John D. Brunzell, John J. Albers   +4 more
doaj   +1 more source

Apolipoprotein M expression increases the size of nascent preβ HDL formed by ATP binding cassette transporter A1

Journal of Lipid Research, 2010
Apolipoprotein M (apoM) is a novel apolipoprotein that is reportedly necessary for preβ HDL formation; however, its detailed function remains unknown. We investigated the biogenesis and properties of apoM and its effects on the initial steps of nascent ...
Anny Mulya, Jeongmin Seo, Amanda L. Brown, Abraham K. Gebre, Elena Boudyguina, Gregory S. Shelness, John S. Parks   +6 more
doaj   +1 more source

Inverse Association Between Serum Non–High‐Density Lipoprotein Cholesterol Levels and Mortality in Patients Undergoing Incident Hemodialysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background There is accumulating evidence that serum levels of non–high‐density lipoprotein cholesterol (non–HDL‐C) are a more accurate predictor of cardiovascular outcomes when compared with low‐density lipoprotein cholesterol.
Tae Ik Chang, Elani Streja, Gang Jee Ko, Neda Naderi, Connie M. Rhee, Csaba P. Kovesdy, Moti L. Kashyap, Nosratola D. Vaziri, Kamyar Kalantar‐Zadeh, Hamid Moradi   +9 more
doaj   +1 more source

Assembly of High-Density Lipoprotein [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2006
Mammalian somatic cells do not catabolize cholesterol and need to export it for its homeostasis at the levels of cells and whole bodies. This reaction may reduce intracellularly accumulated cholesterol in excess and would contribute to prevention or regression of the initial stage of atherosclerosis.
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source