Results 11 to 20 of about 370,627 (265)

Primary genetic disorders affecting high density lipoprotein (HDL)

Drugs in Context, 2018
There is extensive evidence demonstrating that there is a clear inverse correlation between plasma high density lipoprotein cholesterol (HDL-C) concentration and cardiovascular disease (CVD).
Constantine E Kosmas, Delia Silverio, Andreas Sourlas, Frank Garcia, Peter D Montan, Eliscer Guzman   +5 more
doaj   +1 more source

Study of serum lipid profile in the smokers

National Journal of Physiology, Pharmacy and Pharmacology, 2020
Background: Smoking of cigarettes has been found to alter lipoprotein levels. Smoking raises the blood total cholesterol (TC) content, triglycerides (TG), low-density lipoprotein (LDL), and very LDL (VLDL) and reduces the level of good cholesterol, i.e.,
S P Srinivas, Kamble Ganesh
doaj   +1 more source

Coronary risk prediction by the correlation of total cholesterol/high-density lipoprotein, triglyceride/high-density lipoprotein, low-density lipoprotein/high-density lipoprotein ratios, non-high-density lipoprotein, apolipoprotein-B, and high-sensitivity C-reactive protein with low-density lipoprotein in Indian patients under statin therapy

Heart India, 2019
Background: Patients are treated with statins for the control of cholesterol; but statins control only low-density lipoprotein (LDL) and not non-high-density lipoprotein (non-HDL). Also, LDL is not a good coronary risk predictor.
A K Badrinath, K Nagarajan, P Anand, S Suresh Babu, S Asmathulla, M Mohammad Inaamul Hassan   +5 more
doaj   +1 more source

Alternations of Lipoprotein Profiles in the Plasma as Biomarkers of Huntington’s Disease

Cells, 2023
Alterations in lipid composition and disturbed lipoprotein metabolism are involved in the pathomechanism of Huntington’s disease (HD). Here, we measured 112 lipoprotein subfractions and components in the plasma of 20 normal controls, 24 symptomatic ...
Kuo-Hsuan Chang, Mei-Ling Cheng, Chi-Jen Lo, Chun-Ming Fan, Yih-Ru Wu, Chiung-Mei Chen   +5 more
doaj   +1 more source

High Density Lipoproteins and Diabetes

Cells, 2021
Epidemiological studies have established that a high plasma high density lipoprotein cholesterol (HDL-C) level is associated with reduced cardiovascular risk. However, recent randomised clinical trials of interventions that increase HDL-C levels have failed to establish a causal basis for this relationship.
Cochran, BJ, Ong, KL, Manandhar, B, Rye, KA   +3 more
openaire   +4 more sources

High-density lipoprotein cholesterol: How High

Indian Journal of Endocrinology and Metabolism, 2012
The high-density lipoprotein cholesterol (HDL-C) is considered anti-atherogenic good cholesterol. It is involved in reverse transport of lipids. Epidemiological studies have found inverse relationship of HDL-C and coronary heart disease (CHD) risk.
G Rajagopal, V Suresh, Alok Sachan
doaj   +1 more source

Beyond HDL-cholesterol increase: phospholipid enrichment and shift from HDL3 to HDL2 in alcohol consumers

Journal of Lipid Research, 2007
The reduction of cardiovascular mortality associated with moderate alcohol consumption is chiefly thought to be mediated by an increase of high density lipoprotein cholesterol (HDL-CH).
Christian Schäfer, Alexandr Parlesak, Joachim Eckoldt, Christiane Bode, Johann Christian Bode, Winfried März, Karl Winkler   +6 more
doaj   +1 more source

Changes in high-density lipoprotein cholesterol with risk of Cardiovascular Disease among initially high-density lipoprotein-high participants

Cardiovascular Diabetology, 2023
Background High-density lipoprotein cholesterol’s (HDL-C) long-held status as a cardiovascular disease (CVD) preventative has been called into question. Most of the evidence, however, focused on either the risk of death from CVD, or on single time point ...
Hye Jun Kim, Seogsong Jeong, Yun Hwan Oh, Sun Jae Park, Yoosun Cho, Sang Min Park   +5 more
doaj   +1 more source

High-Density Lipoprotein and Heart Failure

Reviews in Cardiovascular Medicine, 2023
The protective effect of high-density lipoprotein (HDL) on atherosclerosis is well known, and its mechanisms of action has been extensively studied. However, the impact of HDL on heart failure and its mechanisms are still controversial or unknown.
Liyun Xing, Yixuan Liu, Jiayu Wang, Peiqing Tian, Ping Liu   +4 more
doaj   +1 more source

Maturation of high-density lipoproteins

Journal of The Royal Society Interface, 2009
Human high-density lipoproteins (HDLs) are involved in the transport of cholesterol. The mechanism by which HDL assembles and functions is not well understood owing to a lack of structural information on circulating spherical HDL. Here, we report a series of molecular dynamics simulations that describe the maturation of discoidal HDL into spherical HDL
Amy Y, Shih, Stephen G, Sligar, Klaus, Schulten   +2 more
openaire   +3 more sources