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High-Density Lipoprotein Mimetics: Focus on Synthetic High-Density Lipoprotein
The American Journal of Cardiology, 2007Epidemiologic studies show an inverse relation between high-density lipoprotein (HDL) cholesterol levels and coronary artery disease, and proof-of-concept experimental studies suggest that HDL and its apolipoproteins, specifically apolipoprotein (apo) A-I , have atheroprotective effects.
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High density lipoprotein in octogenarians
Biochemical Medicine, 1983High density lipoprotein (HDL) cholesterol, total cholesterol, and total triglyceride levels were assayed in the plasma of 42 octogenarians. No differences were found in the levels of HDL cholesterol and total triglycerides when comparing subjects with and without ischemic heart disease.
D, Ron, M, Aviram, J G, Brook
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Exercise and High-Density Lipoproteins
JAMA: The Journal of the American Medical Association, 1979Ever since high-density lipoprotein (HDL)-cholesterol, as a measure of the HDLs, was found to be elevated in crosscountry skiers 1 and marathon runners, 2 investigators have debated whether this is a self-selection phenomenon, ie, skinny athletic persons naturally have higher HDL levels and are attracted to long-distance competitive sports because they
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Diet and high density lipoproteins
Lipids, 1981AbstractThe acute and subacute effects of different diets on serum high density lipoprotein (HDL) cholesterol concentration and/or HDL composition are described. In obese normolipemic, hypercholesterolemic (type II) and hypertriglyceridemic (type IV) patients, low HDL cholesterol values remained low during total starvation for 2 weeks. Prudent diets in
P, Oster +5 more
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Genetics of high-density lipoproteins
Current Opinion in Cardiology, 2006High-density lipoproteins have multi-factorial anti-atherosclerosis properties: they have potent anti-oxidant effects and prevent the oxidation of low-density lipoproteins; they have anti-inflammatory effects; they modulate vascular endothelial cell function and transport cholesterol back to the liver for excretion into the bile - a process called ...
Zari, Dastani +3 more
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High-density lipoproteins and atherosclerosis
The American Journal of Cardiology, 2002High-density lipoproteins (HDLs) are strongly related to risk of atherosclerotic cardiovascular disease. Low levels of HDL cholesterol are a major cardiovascular risk factor, and overexpression of the major HDL protein, apolipoprotein (apo) A-I, markedly inhibits progression and even induces regression of atherosclerosis in animal models. Clinical data
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High Density Lipoproteins in Cholestasis
Scandinavian Journal of Gastroenterology, 1974Blomhoff, J. P. High density lipoproteins in cholestasis. Scand. J. Gastroent. 1974, 9, 591–596.Two patients with cholestasis with increased concentration of plasma free cholesterol and phospholipi...
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High Density Lipoproteins in Diabetes
Diabetes, 1981The concentration of high density lipoproteins (HDL) in patients with diabetes mellitus is highly variable. Subnormal HDL cholesterol levels are present in untreated patients with insulin-deficient juvenile diabetes, but the values return to the normal range after beginning insulin therapy.
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Antidiabetic role of high density lipoproteins
Biomeditsinskaya Khimiya, 2018Disturbance in lipid metabolism can be both a cause and a consequence of the development of diabetes mellitus (DM). One of the most informative indicator of lipid metabolism is the ratio of atherogenic and antiatherogenic fractions of lipoproteins and their protein components.
O N, Poteryaeva, I F, Usynin
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Proteomic analysis of high‐density lipoprotein
PROTEOMICS, 2006AbstractPlasma lipoproteins, such as high‐density lipoprotein (HDL), can serve as carriers for a wide range of proteins that are involved in processes such as lipid metabolism, thrombosis, inflammation and atherosclerosis. The identification of HDL‐associated proteins is essential with regards to understanding these processes at the molecular level. In
Rezaee, Farhad +4 more
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